| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.274683 |
| INTS6 | integrator complex subunit 6 | 0.141904 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.133871 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.125657 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.100991 |
| SMAD3 | SMAD family member 3 | 0.0976278 |
| ANXA2 | annexin A2 | 0.0863966 |
| MYO1E | myosin IE | 0.083385 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0826393 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0798565 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0768534 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0768364 |
| EZR | ezrin | 0.0669895 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0627651 |
| PLSCR2 | phospholipid scramblase 2 | 0.0605132 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0583518 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.058168 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0559179 |
| RNF213 | ring finger protein 213 | 0.0551952 |
| LCN2 | lipocalin 2 | 0.054706 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0540702 |
| EFNB2 | ephrin-B2 | 0.0535801 |
| EXT1 | exostosin glycosyltransferase 1 | 0.052724 |
| ATXN1 | ataxin 1 | 0.0517965 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.05158 |
| MCU | mitochondrial calcium uniporter | 0.0486859 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.04531 |
| VMP1 | vacuole membrane protein 1 | 0.0448379 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0443056 |
| DSCAM | Down syndrome cell adhesion molecule | 0.044133 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0439913 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.043772 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0436815 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0423105 |
| YAP1 | Yes-associated protein 1 | 0.042293 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0419342 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0413608 |
| RUNX1 | runt-related transcription factor 1 | 0.0413131 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0410204 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0399612 |
| TRIM2 | tripartite motif containing 2 | 0.0392931 |
| TJP1 | tight junction protein 1 | 0.0387467 |
| TUFT1 | tuftelin 1 | 0.0382576 |
| DUSP10 | dual specificity phosphatase 10 | 0.0379542 |
| STK24 | serine/threonine kinase 24 | 0.0377374 |
| MYO5B | myosin VB | 0.0370281 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0365889 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0320477 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0319156 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.031776 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0313786 |
| KYNU | kynureninase | 0.0313625 |
| SEPTIN9 | septin 9 | 0.0310818 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0309212 |
| IRF1 | interferon regulatory factor 1 | 0.0308672 |
| TRIB1 | tribbles pseudokinase 1 | 0.0302234 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0300928 |
| VCL | vinculin | 0.0299702 |
| MUC13 | mucin 13, cell surface associated | 0.0294927 |
| SERINC5 | serine incorporator 5 | 0.0290339 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0289047 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0288855 |
| TOX3 | TOX high mobility group box family member 3 | 0.0285004 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0283907 |
| NEBL | nebulette | 0.0274638 |
| ANXA1 | annexin A1 | 0.0272518 |
| SIK3 | SIK family kinase 3 | 0.0272137 |
| HKDC1 | hexokinase domain containing 1 | 0.0271251 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0269515 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0269506 |
| PDZD8 | PDZ domain containing 8 | 0.0267809 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.026435 |
| DPP4 | dipeptidyl-peptidase 4 | 0.02603 |
| ATOSA | atos homolog A | 0.0259522 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0256152 |
| TLE4 | transducin-like enhancer of split 4 | 0.0254778 |
| KIAA1217 | KIAA1217 | 0.0253963 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.025324 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0251858 |
| PMM2 | phosphomannomutase 2 | 0.0250586 |
| GOLGB1 | golgin B1 | 0.0243271 |
| ATF6 | activating transcription factor 6 | 0.0242843 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.02408 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 0.0239902 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0234248 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0233363 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0232074 |
| NABP1 | nucleic acid binding protein 1 | 0.0231952 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0231451 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0230152 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0226906 |
| ATF3 | activating transcription factor 3 | 0.0226886 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.022623 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0225858 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.022327 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0222527 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0220588 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0217867 |
| COG6 | component of oligomeric golgi complex 6 | 0.0215997 |
| NCKAP5 | NCK-associated protein 5 | 0.021556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.142611 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.106717 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0912283 |
| B2M | beta-2-microglobulin | -0.0844254 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0791268 |
| LYZ | lysozyme | -0.0709455 |
| NPSR1 | neuropeptide S receptor 1 | -0.0646885 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0566952 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0552048 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0504037 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0472741 |
| RPS6 | ribosomal protein S6 | -0.0440066 |
| S100A6 | S100 calcium binding protein A6 | -0.0434698 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0414462 |
| SLC38A1 | solute carrier family 38, member 1 | -0.040726 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0397427 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0396325 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0390303 |
| HMGB1 | high mobility group box 1 | -0.0381474 |
| SSH2 | slingshot protein phosphatase 2 | -0.0380807 |
| XAF1 | XIAP associated factor 1 | -0.038023 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0378737 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0374953 |
| DIAPH3 | diaphanous-related formin 3 | -0.0373785 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0368067 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0364853 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0363059 |
| RPL35A | ribosomal protein L35a | -0.03626 |
| PTGR1 | prostaglandin reductase 1 | -0.0351569 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0349421 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0344871 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0342809 |
| RPL34 | ribosomal protein L34 | -0.0330962 |
| EPCAM | epithelial cell adhesion molecule | -0.0321672 |
| TMSB10 | thymosin beta 10 | -0.0315286 |
| BRCA2 | breast cancer 2, early onset | -0.0312136 |
| MKI67 | marker of proliferation Ki-67 | -0.0305851 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0295108 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0294294 |
| TNS4 | tensin 4 | -0.0290728 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0290425 |
| SP100 | SP100 nuclear antigen | -0.0286012 |
| ANXA4 | annexin A4 | -0.0283863 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0282808 |
| DEK | DEK proto-oncogene | -0.027379 |
| ITGA1 | integrin, alpha 1 | -0.027349 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0272602 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0270806 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0267814 |
| TXNRD1 | thioredoxin reductase 1 | -0.0266987 |
| APOL1 | apolipoprotein L, 1 | -0.026593 |
| MUC20 | mucin 20, cell surface associated | -0.0265434 |
| ENO1 | enolase 1, (alpha) | -0.0264028 |
| TFRC | transferrin receptor | -0.0262848 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0259376 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0256502 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255134 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0254728 |
| ITGA6 | integrin, alpha 6 | -0.0252601 |
| RPS24 | ribosomal protein S24 | -0.0251534 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0247485 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0246366 |
| ABLIM1 | actin binding LIM protein 1 | -0.0244447 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0242933 |
| RRM2 | ribonucleotide reductase M2 | -0.0242881 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0242274 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0239767 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0233902 |
| IER3 | immediate early response 3 | -0.0233683 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0233621 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0232773 |
| GLO1 | glyoxalase I | -0.0231604 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0230347 |
| RPL23 | ribosomal protein L23 | -0.0229861 |
| TPM4 | tropomyosin 4 | -0.0226557 |
| HLA-B | major histocompatibility complex, class I, B | -0.0225811 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0225764 |
| MCM3 | minichromosome maintenance complex component 3 | -0.0224555 |
| GNAS | GNAS complex locus | -0.0222965 |
| TRIM56 | tripartite motif containing 56 | -0.0222949 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0222683 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0222508 |
| FTL | ferritin, light polypeptide | -0.0221879 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0218467 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0216242 |
| PMP22 | peripheral myelin protein 22 | -0.0215656 |
| KRT19 | keratin 19, type I | -0.0214784 |
| MX1 | MX dynamin-like GTPase 1 | -0.0213416 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.021322 |
| BRI3BP | BRI3 binding protein | -0.0212231 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0209655 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0206635 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0206185 |
| TMEM123 | transmembrane protein 123 | -0.020385 |
| RPL37A | ribosomal protein L37a | -0.0203446 |
| BRCA1 | breast cancer 1, early onset | -0.0203072 |
| HLA-E | major histocompatibility complex, class I, E | -0.0202302 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0201561 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0200793 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.01998 |
