| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0972543 |
| EZR | ezrin | 0.0907771 |
| LMO7 | LIM domain 7 | 0.0854419 |
| KRT8 | keratin 8, type II | 0.082932 |
| KRT18 | keratin 18, type I | 0.073735 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0675545 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0647316 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0640072 |
| ATXN1 | ataxin 1 | 0.0627032 |
| TMC5 | transmembrane channel-like 5 | 0.0623466 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0607585 |
| RNF213 | ring finger protein 213 | 0.0602422 |
| HLA-B | major histocompatibility complex, class I, B | 0.0585941 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0572755 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.054484 |
| PLEC | plectin | 0.0526715 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0516961 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0490272 |
| B2M | beta-2-microglobulin | 0.0488658 |
| HYOU1 | hypoxia up-regulated 1 | 0.0487124 |
| LCN2 | lipocalin 2 | 0.0484419 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.047417 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0470936 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0464591 |
| EXT1 | exostosin glycosyltransferase 1 | 0.046275 |
| AHR | aryl hydrocarbon receptor | 0.0458537 |
| GDA | guanine deaminase | 0.0453605 |
| SEPTIN9 | septin 9 | 0.0451308 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0449468 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.043962 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0434917 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0433803 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.042506 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0420204 |
| ANXA1 | annexin A1 | 0.0397805 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0395885 |
| MYOF | myoferlin | 0.0378736 |
| PGK1 | phosphoglycerate kinase 1 | 0.0373652 |
| HLA-A | major histocompatibility complex, class I, A | 0.0363523 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0347095 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0328552 |
| CLDN4 | claudin 4 | 0.0325183 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0322057 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0319819 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0307717 |
| RASEF | RAS and EF-hand domain containing | 0.0303903 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0297915 |
| SMAD3 | SMAD family member 3 | 0.02967 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0292311 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0290574 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0289957 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0282999 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0281876 |
| VMP1 | vacuole membrane protein 1 | 0.0281767 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0280716 |
| GPX2 | glutathione peroxidase 2 | 0.0280512 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0279036 |
| MCU | mitochondrial calcium uniporter | 0.0274897 |
| DHFR | dihydrofolate reductase | 0.0272866 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.026893 |
| ATF3 | activating transcription factor 3 | 0.0267989 |
| PMM2 | phosphomannomutase 2 | 0.0266915 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.026595 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0265842 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0262971 |
| BRD2 | bromodomain containing 2 | 0.0262924 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0262456 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0260502 |
| TXNIP | thioredoxin interacting protein | 0.0260113 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0259789 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0257846 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0256408 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0255485 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0252759 |
| AGR3 | anterior gradient 3 | 0.0252348 |
| MUC1 | mucin 1, cell surface associated | 0.0250384 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0244276 |
| STK24 | serine/threonine kinase 24 | 0.0242833 |
| RPN1 | ribophorin I | 0.0241879 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0241763 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0241476 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.024014 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0239906 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0237991 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0237893 |
| TSPAN3 | tetraspanin 3 | 0.0237822 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0236125 |
| CNKSR3 | CNKSR family member 3 | 0.0235605 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0234588 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0234405 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0232882 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0232335 |
| GOLGB1 | golgin B1 | 0.023217 |
| KRT19 | keratin 19, type I | 0.0231803 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0228724 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0228445 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0228397 |
| EXOC6B | exocyst complex component 6B | 0.0227834 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0227262 |
| ANXA11 | annexin A11 | 0.0225642 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.326311 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.225933 |
| PTMA | prothymosin, alpha | -0.199536 |
| ANLN | anillin, actin binding protein | -0.108524 |
| TMSB10 | thymosin beta 10 | -0.0876241 |
| MKI67 | marker of proliferation Ki-67 | -0.0848865 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0822092 |
| TMEM123 | transmembrane protein 123 | -0.0770297 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0755896 |
| DEK | DEK proto-oncogene | -0.0727425 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0712723 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0681806 |
| S100A6 | S100 calcium binding protein A6 | -0.0617404 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0588217 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0580742 |
| DIAPH3 | diaphanous-related formin 3 | -0.0573526 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0531362 |
| RPLP1 | ribosomal protein, large, P1 | -0.0524192 |
| EHBP1 | EH domain binding protein 1 | -0.0523146 |
| RRM2 | ribonucleotide reductase M2 | -0.0518694 |
| S100A10 | S100 calcium binding protein A10 | -0.0513334 |
| GNAS | GNAS complex locus | -0.051177 |
| H1-0 | H1.0 linker histone | -0.0509044 |
| HMGA1 | high mobility group AT-hook 1 | -0.0508182 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0495948 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0470448 |
| HMGB1 | high mobility group box 1 | -0.0458433 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0452665 |
| BRCA1 | breast cancer 1, early onset | -0.0439191 |
| RPS24 | ribosomal protein S24 | -0.0430746 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0424633 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0413838 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0410385 |
| WDR45B | WD repeat domain 45B | -0.0405122 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0401093 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0400852 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0394875 |
| EPCAM | epithelial cell adhesion molecule | -0.0394722 |
| ITGA6 | integrin, alpha 6 | -0.0390993 |
| ECT2 | epithelial cell transforming 2 | -0.0390392 |
| TPX2 | TPX2, microtubule-associated | -0.0386968 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0381613 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0371408 |
| TUBA1B | tubulin, alpha 1b | -0.0370295 |
| CBX3 | chromobox homolog 3 | -0.0369798 |
| TES | testin LIM domain protein | -0.0367004 |
| RAI1 | retinoic acid induced 1 | -0.0365832 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0365724 |
| RPS25 | ribosomal protein S25 | -0.0358293 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0345303 |
| HMGB2 | high mobility group box 2 | -0.0342645 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0338529 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.033756 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0335829 |
| TFRC | transferrin receptor | -0.0334065 |
| CENPP | centromere protein P | -0.0332597 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0322291 |
| FRMD5 | FERM domain containing 5 | -0.0319254 |
| RPL34 | ribosomal protein L34 | -0.0316339 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0316127 |
| TPM4 | tropomyosin 4 | -0.0313652 |
| RPS6 | ribosomal protein S6 | -0.0307028 |
| CENPF | centromere protein F, 350/400kDa | -0.0305857 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0303427 |
| FANCI | Fanconi anemia, complementation group I | -0.0292278 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0290995 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0287142 |
| ANXA2 | annexin A2 | -0.0286899 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0285671 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0285663 |
| AHNAK | AHNAK nucleoprotein | -0.0285525 |
| RPL12 | ribosomal protein L12 | -0.0279941 |
| FLNB | filamin B, beta | -0.0277966 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.027124 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0268676 |
| S100A11 | S100 calcium binding protein A11 | -0.0268122 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0267849 |
| RAD51B | RAD51 paralog B | -0.0264753 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0262747 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0262655 |
| ASPH | aspartate beta-hydroxylase | -0.0262333 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0261539 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0260585 |
| CCND1 | cyclin D1 | -0.0258909 |
| RPS19 | ribosomal protein S19 | -0.0258621 |
| HELLS | helicase, lymphoid-specific | -0.0258183 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0257431 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0257183 |
| RPL35A | ribosomal protein L35a | -0.0256557 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0254072 |
| XPO1 | exportin 1 | -0.0253426 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0251899 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0249219 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.024887 |
| RPS21 | ribosomal protein S21 | -0.0245975 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.024593 |
| AGR2 | anterior gradient 2 | -0.0242698 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0241377 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0238857 |
| KLK10 | kallikrein-related peptidase 10 | -0.0238069 |
