| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0720205 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0551755 |
| CAPRIN2 | caprin family member 2 | 0.048482 |
| HLA-B | major histocompatibility complex, class I, B | 0.0474285 |
| PRELID2 | PRELI domain containing 2 | 0.0326935 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0304659 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0270557 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0267775 |
| SQSTM1 | sequestosome 1 | 0.0242987 |
| MYOF | myoferlin | 0.024294 |
| HOMER1 | homer scaffolding protein 1 | 0.0240078 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0235422 |
| TGM2 | transglutaminase 2 | 0.0235032 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0233351 |
| SPAG9 | sperm associated antigen 9 | 0.0218218 |
| HDAC9 | histone deacetylase 9 | 0.0216039 |
| INTS6 | integrator complex subunit 6 | 0.0214366 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0212424 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0207488 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0205515 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0202106 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0197629 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0194945 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0193145 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0189235 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0189229 |
| PLEC | plectin | 0.01888 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0188303 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0184618 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0171524 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0170711 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0166811 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0166767 |
| TNS3 | tensin 3 | 0.0165112 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0160836 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0158173 |
| RPS12 | ribosomal protein S12 | 0.0156055 |
| ARRDC3 | arrestin domain containing 3 | 0.0148338 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0147841 |
| NDRG1 | N-myc downstream regulated 1 | 0.01432 |
| ATF3 | activating transcription factor 3 | 0.0142924 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0142664 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0140748 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0140227 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0139419 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0138603 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0136755 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.013612 |
| ARFGEF3 | ARFGEF family member 3 | 0.0135359 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0132826 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0131349 |
| ZNF638 | zinc finger protein 638 | 0.0128629 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0127209 |
| EGR1 | early growth response 1 | 0.0125132 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0124487 |
| SMAD3 | SMAD family member 3 | 0.0122579 |
| PRKCE | protein kinase C, epsilon | 0.0122413 |
| NEK10 | NIMA-related kinase 10 | 0.0120451 |
| LOXL2 | lysyl oxidase-like 2 | 0.0120351 |
| GOLGB1 | golgin B1 | 0.0120244 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0118968 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.011843 |
| HLA-C | major histocompatibility complex, class I, C | 0.0116793 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0116722 |
| JMJD1C | jumonji domain containing 1C | 0.0116701 |
| TXNIP | thioredoxin interacting protein | 0.0115775 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0115695 |
| LRRC23 | leucine rich repeat containing 23 | 0.0115694 |
| CTBP2 | C-terminal binding protein 2 | 0.0115263 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0114452 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0113881 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0113102 |
| ADM | adrenomedullin | 0.0111376 |
| HLA-A | major histocompatibility complex, class I, A | 0.0108883 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0108224 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0105208 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0105104 |
| OPTN | optineurin | 0.0103855 |
| VEGFA | vascular endothelial growth factor A | 0.0103336 |
| FAM219A | family with sequence similarity 219, member A | 0.010182 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0101475 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0100974 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0100628 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0100271 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00988819 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.00987603 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.00986651 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.00975034 |
| SVIL | supervillin | 0.00974983 |
| BRD2 | bromodomain containing 2 | 0.00974745 |
| ANK2 | ankyrin 2, neuronal | 0.00973322 |
| IRF1 | interferon regulatory factor 1 | 0.00955824 |
| ANKRD36 | ankyrin repeat domain 36 | 0.00945187 |
| PDE8A | phosphodiesterase 8A | 0.00941947 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00937786 |
| CRY1 | cryptochrome circadian clock 1 | 0.00934474 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.00928097 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00926357 |
| SGMS2 | sphingomyelin synthase 2 | 0.00923239 |
| NOCT | nocturnin | 0.00893231 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.271068 |
| PTMA | prothymosin, alpha | -0.118693 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.093715 |
| RAI1 | retinoic acid induced 1 | -0.0873393 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0833316 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0798467 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0743246 |
| TXNRD1 | thioredoxin reductase 1 | -0.0714741 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0703424 |
| CENPF | centromere protein F, 350/400kDa | -0.0670333 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0662913 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0652433 |
| CD44 | CD44 molecule (Indian blood group) | -0.0585915 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0549137 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0533389 |
| CANX | calnexin | -0.0529773 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.048901 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0482921 |
| MKI67 | marker of proliferation Ki-67 | -0.0475493 |
| MT2A | metallothionein 2A | -0.0469196 |
| TMSB10 | thymosin beta 10 | -0.0457702 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0451309 |
| AHNAK | AHNAK nucleoprotein | -0.0445302 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0425937 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0422769 |
| EHBP1 | EH domain binding protein 1 | -0.0419484 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0402842 |
| ENO1 | enolase 1, (alpha) | -0.0398924 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0388953 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0379919 |
| POTEF | POTE ankyrin domain family, member F | -0.0375075 |
| APP | amyloid beta (A4) precursor protein | -0.03737 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0366341 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0363392 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0359966 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0345211 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.034052 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0329328 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0322256 |
| DIAPH3 | diaphanous-related formin 3 | -0.0311637 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0308435 |
| TOP1 | topoisomerase (DNA) I | -0.0300215 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0299878 |
| SRGN | serglycin | -0.0297541 |
| RBM25 | RNA binding motif protein 25 | -0.0297078 |
| LDHA | lactate dehydrogenase A | -0.0295607 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0294615 |
| RIGI | RNA sensor RIG-I | -0.0294383 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0292574 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0286811 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0280152 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0278496 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0277235 |
| ANLN | anillin, actin binding protein | -0.0275428 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0273788 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0268207 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0267566 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0265786 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264179 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.026312 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0260476 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0258333 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0255673 |
| TMEM123 | transmembrane protein 123 | -0.0255057 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0253422 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0252564 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.025064 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0249604 |
| SEPTIN7 | septin 7 | -0.0247253 |
| XPO1 | exportin 1 | -0.0245839 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0245785 |
| ACTG1 | actin gamma 1 | -0.0245047 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0242449 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0240821 |
| TMSB4X | thymosin beta 4, X-linked | -0.0238084 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0234543 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0230031 |
| IPO7 | importin 7 | -0.0229852 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0228246 |
| TPX2 | TPX2, microtubule-associated | -0.0228178 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0225668 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0224672 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0222286 |
| SRPK2 | SRSF protein kinase 2 | -0.0220546 |
| RTN4 | reticulon 4 | -0.0219957 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0216666 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0216536 |
| FBXO11 | F-box protein 11 | -0.0215752 |
| HMGA1 | high mobility group AT-hook 1 | -0.0215478 |
| SET | SET nuclear proto-oncogene | -0.0215228 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0213097 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0211291 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0210682 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0210424 |
| CDK6 | cyclin-dependent kinase 6 | -0.0209693 |
| TPM4 | tropomyosin 4 | -0.0208125 |
| RACK1 | receptor for activated C kinase 1 | -0.0207969 |
| THOC2 | THO complex 2 | -0.0205752 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0205451 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0205037 |
