| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.152127 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.141236 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.138237 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.123779 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.11237 |
| GRB10 | growth factor receptor-bound protein 10 | 0.111946 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.10624 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0926178 |
| LOX | lysyl oxidase | 0.0908231 |
| TMSB10 | thymosin beta 10 | 0.0904191 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0882659 |
| VIM | vimentin | 0.0877353 |
| FAM20C | family with sequence similarity 20, member C | 0.0843241 |
| NAV2 | neuron navigator 2 | 0.0840932 |
| LOXL2 | lysyl oxidase-like 2 | 0.0783569 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0779822 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0776794 |
| CDH13 | cadherin 13 | 0.0759874 |
| CD44 | CD44 molecule (Indian blood group) | 0.0735474 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0690405 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0674393 |
| FAM107B | family with sequence similarity 107, member B | 0.0662801 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0659841 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.065983 |
| HMGA2 | high mobility group AT-hook 2 | 0.0649532 |
| SMAD3 | SMAD family member 3 | 0.0620198 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0618374 |
| CA12 | carbonic anhydrase XII | 0.0615095 |
| SEPTIN9 | septin 9 | 0.0612815 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0611737 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0593913 |
| PGK1 | phosphoglycerate kinase 1 | 0.0583753 |
| RAI14 | retinoic acid induced 14 | 0.0580551 |
| AHNAK | AHNAK nucleoprotein | 0.0558186 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0550438 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0545919 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0545581 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0534283 |
| TGFB1 | transforming growth factor, beta 1 | 0.0505905 |
| FBN1 | fibrillin 1 | 0.0502164 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0493432 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0459933 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0457526 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0457214 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0456607 |
| SYT1 | synaptotagmin I | 0.0453438 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.044242 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0440338 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.04386 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0428236 |
| SQSTM1 | sequestosome 1 | 0.0425434 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0424 |
| STC1 | stanniocalcin 1 | 0.0418257 |
| ATXN1 | ataxin 1 | 0.0417627 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0409114 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0407922 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0406329 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0404261 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.040339 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0403332 |
| SVIL | supervillin | 0.0402939 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0402616 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.040092 |
| MAP1B | microtubule-associated protein 1B | 0.0400712 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0397242 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0395724 |
| MEF2A | myocyte enhancer factor 2A | 0.0392184 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0391767 |
| NDRG1 | N-myc downstream regulated 1 | 0.0388963 |
| HLA-B | major histocompatibility complex, class I, B | 0.0382927 |
| RNF213 | ring finger protein 213 | 0.0378452 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0378015 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0373078 |
| ENO1 | enolase 1, (alpha) | 0.0372254 |
| PLIN2 | perilipin 2 | 0.0370113 |
| PLEC | plectin | 0.0369502 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.036874 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0364508 |
| EMP1 | epithelial membrane protein 1 | 0.036444 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0358241 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0356573 |
| EGFR | epidermal growth factor receptor | 0.0356235 |
| EZR | ezrin | 0.0355956 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0354614 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0353009 |
| LDHA | lactate dehydrogenase A | 0.0350326 |
| PFKP | phosphofructokinase, platelet | 0.0349442 |
| SYNJ2 | synaptojanin 2 | 0.0346365 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0343036 |
| JUN | jun proto-oncogene | 0.0340794 |
| ANGPTL4 | angiopoietin-like 4 | 0.0339731 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0332996 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0332383 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0331528 |
| NRG1 | neuregulin 1 | 0.0326503 |
| EHBP1 | EH domain binding protein 1 | 0.0325629 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0324691 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0323788 |
| PRKCA | protein kinase C, alpha | 0.0322322 |
| NAV1 | neuron navigator 1 | 0.031855 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.14365 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.108027 |
| RBM39 | RNA binding motif protein 39 | -0.0910015 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0526085 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0523196 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0507985 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.04908 |
| USP34 | ubiquitin specific peptidase 34 | -0.0475884 |
| GOLGA4 | golgin A4 | -0.0444353 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0414016 |
| RPS2 | ribosomal protein S2 | -0.0394983 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0378319 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.037727 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0359879 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0338555 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0326932 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0313613 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0310871 |
| SPAG9 | sperm associated antigen 9 | -0.0309783 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.030792 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0307607 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0298389 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0293095 |
| MT2A | metallothionein 2A | -0.0292155 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0290039 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0289448 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0281842 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0275532 |
| PCNX1 | pecanex 1 | -0.0274608 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0274327 |
| SBF2 | SET binding factor 2 | -0.0270082 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0267902 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0267717 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0262199 |
| NCOA7 | nuclear receptor coactivator 7 | -0.025065 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0250072 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0249075 |
| PHIP | pleckstrin homology domain interacting protein | -0.0248815 |
| NEK7 | NIMA-related kinase 7 | -0.0248624 |
| COG5 | component of oligomeric golgi complex 5 | -0.0248226 |
| CCNL1 | cyclin L1 | -0.0246386 |
| XPO1 | exportin 1 | -0.0245017 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0243759 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0241861 |
| STK38L | serine/threonine kinase 38 like | -0.0237242 |
| SRP54 | signal recognition particle 54kDa | -0.0236935 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0235749 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0234736 |
| RBM25 | RNA binding motif protein 25 | -0.0233422 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0228875 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.022746 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0224956 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.022426 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.022196 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0217369 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0216415 |
| MSN | moesin | -0.021376 |
| JAK1 | Janus kinase 1 | -0.021176 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0210659 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0209203 |
| AHR | aryl hydrocarbon receptor | -0.0208569 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0208431 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.020664 |
| OGA | O-GlcNAcase | -0.0206603 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0204062 |
| HELZ | helicase with zinc finger | -0.0203269 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0203031 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0202715 |
| JMJD1C | jumonji domain containing 1C | -0.0201647 |
| HAS2 | hyaluronan synthase 2 | -0.0199597 |
| ATP13A3 | ATPase type 13A3 | -0.0198223 |
| USP3 | ubiquitin specific peptidase 3 | -0.0196333 |
| PTMA | prothymosin, alpha | -0.0196153 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0195962 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.019505 |
| RNF145 | ring finger protein 145 | -0.0193085 |
| FAM3C | family with sequence similarity 3, member C | -0.0192567 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0192103 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0190689 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0190522 |
| YBX3 | Y box binding protein 3 | -0.0188041 |
| RASA2 | RAS p21 protein activator 2 | -0.0186657 |
| UBXN4 | UBX domain protein 4 | -0.0186522 |
| SEPTIN7 | septin 7 | -0.0186367 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0186285 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0185255 |
| SUCO | SUN domain containing ossification factor | -0.0185092 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0184207 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0183952 |
| FOXJ3 | forkhead box J3 | -0.0183717 |
| RNF149 | ring finger protein 149 | -0.0183458 |
| PDE8A | phosphodiesterase 8A | -0.0181893 |
| CLTC | clathrin, heavy chain (Hc) | -0.0181711 |
| CDK17 | cyclin-dependent kinase 17 | -0.018095 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0177843 |
| NEMF | nuclear export mediator factor | -0.0176565 |
| PNN | pinin, desmosome associated protein | -0.0176038 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0175708 |
| CDC73 | cell division cycle 73 | -0.0175583 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0173483 |
