| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.105273 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0880069 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0873416 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.086992 |
| NAV2 | neuron navigator 2 | 0.0832755 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.072988 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0721432 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0685913 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0645644 |
| SQSTM1 | sequestosome 1 | 0.0538735 |
| SMAD3 | SMAD family member 3 | 0.052723 |
| HDAC9 | histone deacetylase 9 | 0.0508479 |
| FNIP1 | folliculin interacting protein 1 | 0.0480603 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0476105 |
| HLA-B | major histocompatibility complex, class I, B | 0.0475492 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0473237 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0464315 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0437255 |
| OGA | O-GlcNAcase | 0.0435259 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0417413 |
| NDRG1 | N-myc downstream regulated 1 | 0.0410965 |
| PRELID2 | PRELI domain containing 2 | 0.0410898 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0409224 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0393071 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0384337 |
| RND3 | Rho family GTPase 3 | 0.03784 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0376388 |
| PGK1 | phosphoglycerate kinase 1 | 0.0357671 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0342998 |
| FMNL2 | formin-like 2 | 0.0328683 |
| PDE10A | phosphodiesterase 10A | 0.0320879 |
| JMJD1C | jumonji domain containing 1C | 0.0320136 |
| ARRDC3 | arrestin domain containing 3 | 0.0316903 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0315084 |
| FOXO3 | forkhead box O3 | 0.0302233 |
| ARFGEF3 | ARFGEF family member 3 | 0.0299454 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0298162 |
| FLNA | filamin A, alpha | 0.0295379 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0290174 |
| ATXN1 | ataxin 1 | 0.0287099 |
| DUSP10 | dual specificity phosphatase 10 | 0.0285988 |
| ADM | adrenomedullin | 0.028463 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0282412 |
| RUNX1 | runt-related transcription factor 1 | 0.0278748 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0278482 |
| GOLGB1 | golgin B1 | 0.0277706 |
| OPTN | optineurin | 0.0276633 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0274531 |
| MYOF | myoferlin | 0.0272624 |
| FAM219A | family with sequence similarity 219, member A | 0.0268331 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0265534 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0262221 |
| CEP250 | centrosomal protein 250kDa | 0.0262042 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0260879 |
| HLA-C | major histocompatibility complex, class I, C | 0.0260214 |
| ZNF292 | zinc finger protein 292 | 0.0256915 |
| HELZ | helicase with zinc finger | 0.0256375 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0255087 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0252958 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0252673 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0249509 |
| YEATS2 | YEATS domain containing 2 | 0.0249245 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0248553 |
| CANX | calnexin | 0.0248499 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0244792 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.023892 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0238634 |
| SPAG9 | sperm associated antigen 9 | 0.0233692 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0233425 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0231709 |
| ATF3 | activating transcription factor 3 | 0.0230031 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0229793 |
| FLNB | filamin B, beta | 0.0229732 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0228838 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0224047 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0223803 |
| AHR | aryl hydrocarbon receptor | 0.0222178 |
| INTS6 | integrator complex subunit 6 | 0.0222069 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0221154 |
| TRAM2 | translocation associated membrane protein 2 | 0.0217328 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0215542 |
| MLPH | melanophilin | 0.0213179 |
| ZNF638 | zinc finger protein 638 | 0.020882 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0205551 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0203706 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0201762 |
| SFTPA2 | surfactant protein A2 | 0.0200121 |
| NOTCH2 | notch 2 | 0.0199978 |
| KYNU | kynureninase | 0.0197586 |
| PCBP3 | poly(rC) binding protein 3 | 0.0197078 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0197032 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0196784 |
| APP | amyloid beta (A4) precursor protein | 0.0194585 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0194365 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0193738 |
| BRD2 | bromodomain containing 2 | 0.0192832 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0192782 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0191862 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0191782 |
| ANXA1 | annexin A1 | 0.0189554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.260375 |
| FRMD4A | FERM domain containing 4A | -0.171714 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0962812 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0955283 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0894931 |
| GLIS3 | GLIS family zinc finger 3 | -0.0842557 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0633296 |
| TMSB10 | thymosin beta 10 | -0.0601572 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0558562 |
| FN1 | fibronectin 1 | -0.0532765 |
| VCAN | versican | -0.0529241 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0527653 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0504551 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0501233 |
| IER3 | immediate early response 3 | -0.0488798 |
| CD44 | CD44 molecule (Indian blood group) | -0.0471956 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0467778 |
| TPM4 | tropomyosin 4 | -0.0464268 |
| VCL | vinculin | -0.0445278 |
| PTMA | prothymosin, alpha | -0.0445019 |
| HMGA2 | high mobility group AT-hook 2 | -0.0437603 |
| FTL | ferritin, light polypeptide | -0.0430382 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0417151 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0411522 |
| BICC1 | BicC family RNA binding protein 1 | -0.0379816 |
| RAI14 | retinoic acid induced 14 | -0.0377972 |
| DIAPH2 | diaphanous-related formin 2 | -0.0361212 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0361174 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0356143 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0353365 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0351579 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0349731 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0349223 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0342959 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0332792 |
| EGR1 | early growth response 1 | -0.0324637 |
| MKI67 | marker of proliferation Ki-67 | -0.0319039 |
| GNAS | GNAS complex locus | -0.0305725 |
| CLMP | CXADR-like membrane protein | -0.0298788 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0297654 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0295951 |
| RTN4 | reticulon 4 | -0.0289878 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0278569 |
| HMGA1 | high mobility group AT-hook 1 | -0.0272698 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0272527 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.027008 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0268103 |
| COL1A1 | collagen, type I, alpha 1 | -0.0265744 |
| RAI1 | retinoic acid induced 1 | -0.0261383 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0251749 |
| TENM2 | teneurin transmembrane protein 2 | -0.0251251 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0250043 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0248154 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0248132 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0245077 |
| IL6 | interleukin 6 | -0.0241099 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0238048 |
| CTSD | cathepsin D | -0.0237354 |
| DEK | DEK proto-oncogene | -0.0235989 |
| KRT19 | keratin 19, type I | -0.0222168 |
| COL1A2 | collagen, type I, alpha 2 | -0.0219673 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0217788 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0211861 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0210066 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0208298 |
| DIAPH3 | diaphanous-related formin 3 | -0.0207898 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.020542 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.020252 |
| TNNC1 | troponin C type 1 (slow) | -0.0200993 |
| BNC2 | basonuclin 2 | -0.0199677 |
| CENPF | centromere protein F, 350/400kDa | -0.019934 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.019636 |
| DST | dystonin | -0.0195056 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0192872 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0190978 |
| LOX | lysyl oxidase | -0.0190369 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.018796 |
| THBS1 | thrombospondin 1 | -0.018538 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0184542 |
| RPS24 | ribosomal protein S24 | -0.0182614 |
| TUBB | tubulin, beta class I | -0.0182036 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0181796 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0181777 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0180934 |
| TPM1 | tropomyosin 1 (alpha) | -0.0175505 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0174266 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0173606 |
| CBX3 | chromobox homolog 3 | -0.0172806 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0172038 |
| RPLP1 | ribosomal protein, large, P1 | -0.0171563 |
| CALD1 | caldesmon 1 | -0.0171485 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0168854 |
| NAV1 | neuron navigator 1 | -0.0167623 |
| TXNRD1 | thioredoxin reductase 1 | -0.0166915 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0164611 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0163281 |
| RPS6 | ribosomal protein S6 | -0.0162509 |
| EHBP1 | EH domain binding protein 1 | -0.0162254 |
| S100A9 | S100 calcium binding protein A9 | -0.0162104 |
| ERBIN | erbb2 interacting protein | -0.0161797 |
