| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.331055 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.131149 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.124992 |
| NDRG1 | N-myc downstream regulated 1 | 0.12395 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.121784 |
| FAM13A | family with sequence similarity 13, member A | 0.114193 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.104813 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.104169 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.100452 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0938623 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0922245 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0888611 |
| ARRDC3 | arrestin domain containing 3 | 0.088802 |
| ADM | adrenomedullin | 0.0870916 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0831357 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0813885 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0811569 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0741157 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0726879 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0675337 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0606748 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0605999 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0602441 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0601525 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0600254 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0592744 |
| ZNF292 | zinc finger protein 292 | 0.0587817 |
| HLA-B | major histocompatibility complex, class I, B | 0.0576539 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0571208 |
| COPA | coatomer protein complex, subunit alpha | 0.0567376 |
| RND3 | Rho family GTPase 3 | 0.0512348 |
| SMAD3 | SMAD family member 3 | 0.0489706 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0484571 |
| ANXA2 | annexin A2 | 0.0478581 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0474285 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0463459 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0458024 |
| NRXN3 | neurexin 3 | 0.0435083 |
| RNF24 | ring finger protein 24 | 0.0424657 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0421766 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0420032 |
| PKM | pyruvate kinase, muscle | 0.0409033 |
| EPAS1 | endothelial PAS domain protein 1 | 0.040728 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0405305 |
| COG5 | component of oligomeric golgi complex 5 | 0.0404992 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0403361 |
| PLEC | plectin | 0.0403294 |
| ZNF395 | zinc finger protein 395 | 0.0396683 |
| OGA | O-GlcNAcase | 0.0396322 |
| RNF145 | ring finger protein 145 | 0.0396225 |
| HELZ | helicase with zinc finger | 0.0393883 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0388285 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0387769 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.038144 |
| LOXL2 | lysyl oxidase-like 2 | 0.0376287 |
| MATR3 | matrin 3 | 0.0375639 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0374766 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0374534 |
| RLF | rearranged L-myc fusion | 0.0374103 |
| CALR | calreticulin | 0.037124 |
| FLNA | filamin A, alpha | 0.0369895 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0369067 |
| CADM1 | cell adhesion molecule 1 | 0.0361029 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0355417 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0352604 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0350751 |
| PGK1 | phosphoglycerate kinase 1 | 0.0349458 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0348204 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0345283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0340799 |
| ANXA1 | annexin A1 | 0.0337419 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0334795 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0334447 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0333504 |
| TXNIP | thioredoxin interacting protein | 0.0332472 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0330028 |
| B2M | beta-2-microglobulin | 0.0329477 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0328872 |
| RBM39 | RNA binding motif protein 39 | 0.032535 |
| SEC24D | SEC24 family member D | 0.0320192 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0312879 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0311319 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0308697 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.030827 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0307561 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0300899 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.02997 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0298053 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.029803 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0297694 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0295081 |
| HBP1 | HMG-box transcription factor 1 | 0.0293071 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0292968 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0290727 |
| SEPTIN9 | septin 9 | 0.0290383 |
| UBC | ubiquitin C | 0.0289841 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0287677 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0287049 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0286874 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0286873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.125928 |
| FN1 | fibronectin 1 | -0.100288 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.100055 |
| MT2A | metallothionein 2A | -0.0968098 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0838251 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0754784 |
| CDH13 | cadherin 13 | -0.0699018 |
| LOX | lysyl oxidase | -0.0683375 |
| HMGA2 | high mobility group AT-hook 2 | -0.0670786 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.065089 |
| POTEF | POTE ankyrin domain family, member F | -0.0537845 |
| TMSB10 | thymosin beta 10 | -0.0523411 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0510147 |
| VCL | vinculin | -0.0485072 |
| ENO1 | enolase 1, (alpha) | -0.0472623 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0412757 |
| PRSS23 | protease, serine, 23 | -0.0403267 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0399765 |
| ASPH | aspartate beta-hydroxylase | -0.0392241 |
| FBXO11 | F-box protein 11 | -0.0374922 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0366566 |
| RAI14 | retinoic acid induced 14 | -0.0366271 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0357396 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.034851 |
| PTMA | prothymosin, alpha | -0.0341045 |
| COL1A2 | collagen, type I, alpha 2 | -0.0315441 |
| RAD51B | RAD51 paralog B | -0.0310032 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0305092 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0294218 |
| CDK13 | cyclin-dependent kinase 13 | -0.0284918 |
| TPM1 | tropomyosin 1 (alpha) | -0.0283622 |
| GNAS | GNAS complex locus | -0.0282434 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0281073 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0280788 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0277508 |
| S100A6 | S100 calcium binding protein A6 | -0.026696 |
| DIAPH3 | diaphanous-related formin 3 | -0.0259855 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0256208 |
| CCDC88A | coiled-coil domain containing 88A | -0.0254666 |
| OSMR | oncostatin M receptor | -0.0248334 |
| TPM4 | tropomyosin 4 | -0.0246768 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0243802 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.024039 |
| CDK6 | cyclin-dependent kinase 6 | -0.0233937 |
| ACTG1 | actin gamma 1 | -0.0231469 |
| VEGFC | vascular endothelial growth factor C | -0.0230156 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0227353 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0226839 |
| MKI67 | marker of proliferation Ki-67 | -0.0224792 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0223344 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0222765 |
| COL5A2 | collagen, type V, alpha 2 | -0.022137 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0221088 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0211195 |
| CENPF | centromere protein F, 350/400kDa | -0.0209263 |
| RASAL2 | RAS protein activator like 2 | -0.0207711 |
| TUBA1B | tubulin, alpha 1b | -0.0204949 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0204505 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0203089 |
| RASA2 | RAS p21 protein activator 2 | -0.0202516 |
| EFNA5 | ephrin-A5 | -0.0202204 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0201368 |
| RPLP1 | ribosomal protein, large, P1 | -0.0201026 |
| CCM2 | cerebral cavernous malformation 2 | -0.0195901 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.019573 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0195648 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0193612 |
| PDE10A | phosphodiesterase 10A | -0.0193456 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0192176 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.0189907 |
| LAMB1 | laminin, beta 1 | -0.0189219 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0188495 |
| RPL31 | ribosomal protein L31 | -0.0188064 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0187972 |
| CCDC18 | coiled-coil domain containing 18 | -0.0187871 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0185848 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0185483 |
| CCND1 | cyclin D1 | -0.0182619 |
| EHBP1 | EH domain binding protein 1 | -0.0181858 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0181355 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0180777 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0179281 |
| PCNX4 | pecanex 4 | -0.0178802 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0177286 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.017661 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0176354 |
| INHBA | inhibin, beta A | -0.0174884 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0173057 |
| CLIC4 | chloride intracellular channel 4 | -0.0171181 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0170681 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0168735 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | -0.0168581 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0168081 |
| NRP1 | neuropilin 1 | -0.0167227 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0166324 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0163859 |
| PYGL | phosphorylase, glycogen, liver | -0.0163789 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0162993 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0161858 |
| CDK14 | cyclin-dependent kinase 14 | -0.0161109 |
