| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.136739 |
| SMAD3 | SMAD family member 3 | 0.0829699 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0770392 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0715557 |
| SQSTM1 | sequestosome 1 | 0.0675334 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0670735 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0639757 |
| ANXA1 | annexin A1 | 0.0629142 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0589415 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0584418 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0549727 |
| PLEC | plectin | 0.0520938 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0503466 |
| SVIL | supervillin | 0.0492615 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0480228 |
| HLA-B | major histocompatibility complex, class I, B | 0.0472344 |
| PRKCA | protein kinase C, alpha | 0.0470214 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0465149 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.04637 |
| ZNF638 | zinc finger protein 638 | 0.0460669 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0447888 |
| CEP250 | centrosomal protein 250kDa | 0.0430802 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.043016 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0421213 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0414486 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0412497 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0408487 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0407751 |
| SON | SON DNA binding protein | 0.0406472 |
| TLE4 | transducin-like enhancer of split 4 | 0.0401458 |
| RUNX1 | runt-related transcription factor 1 | 0.0401254 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.040011 |
| HLA-A | major histocompatibility complex, class I, A | 0.0379757 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0370559 |
| FNIP1 | folliculin interacting protein 1 | 0.0369436 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0359756 |
| ANO6 | anoctamin 6 | 0.0358518 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0346263 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0345344 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0334306 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0328848 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0328175 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0324715 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0321864 |
| GOLGA4 | golgin A4 | 0.0318641 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0317447 |
| AHR | aryl hydrocarbon receptor | 0.0315297 |
| EZR | ezrin | 0.0310961 |
| IDS | iduronate 2-sulfatase | 0.0310017 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0306685 |
| B2M | beta-2-microglobulin | 0.0305464 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0305243 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0299401 |
| KLHL29 | kelch-like family member 29 | 0.0287442 |
| BRD2 | bromodomain containing 2 | 0.0286202 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.028517 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0280913 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0273684 |
| RNF145 | ring finger protein 145 | 0.0272639 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.0271843 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0271829 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0271151 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.026882 |
| CTTN | cortactin | 0.0268246 |
| CPNE1 | copine I | 0.0268111 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0267554 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0267327 |
| GOLGB1 | golgin B1 | 0.0265712 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0265113 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0263538 |
| FMNL2 | formin-like 2 | 0.0261722 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0259027 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0257205 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0255807 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0255216 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0254728 |
| WHRN | whirlin | 0.0249722 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0249016 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0248785 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0247405 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0246235 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0246161 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0245002 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0243993 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.0243289 |
| WWOX | WW domain containing oxidoreductase | 0.0242622 |
| DCUN1D5 | DCN1, defective in cullin neddylation 1, domain containing 5 | 0.0237147 |
| JMJD1C | jumonji domain containing 1C | 0.0236767 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0234558 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0232364 |
| EXOC6B | exocyst complex component 6B | 0.023204 |
| DIAPH1 | diaphanous-related formin 1 | 0.0231992 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0231007 |
| TRAM2 | translocation associated membrane protein 2 | 0.0228186 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0227756 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0227552 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0226068 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0225484 |
| OPTN | optineurin | 0.0225446 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.0225147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.192866 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134405 |
| PTMA | prothymosin, alpha | -0.10293 |
| TMSB10 | thymosin beta 10 | -0.0944153 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0858588 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0816426 |
| LDHA | lactate dehydrogenase A | -0.0717253 |
| HMGA2 | high mobility group AT-hook 2 | -0.0652145 |
| TPM4 | tropomyosin 4 | -0.0633404 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0620323 |
| SDC4 | syndecan 4 | -0.06001 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.059712 |
| DNER | delta/notch-like EGF repeat containing | -0.05879 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0576537 |
| RAI14 | retinoic acid induced 14 | -0.0568849 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0549924 |
| MT2A | metallothionein 2A | -0.0544311 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0530917 |
| CANX | calnexin | -0.0518606 |
| CD44 | CD44 molecule (Indian blood group) | -0.0518432 |
| TMEM123 | transmembrane protein 123 | -0.05172 |
| NDRG1 | N-myc downstream regulated 1 | -0.0484372 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0477326 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0434212 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0430335 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0429076 |
| FMN1 | formin 1 | -0.0425418 |
| SEPTIN7 | septin 7 | -0.0417575 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0415551 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0403057 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0400802 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0400185 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0399548 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0398481 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0391996 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0391905 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0385859 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0373723 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0370079 |
| FLNB | filamin B, beta | -0.0368275 |
| PRELID2 | PRELI domain containing 2 | -0.0355742 |
| IGF2 | insulin-like growth factor 2 | -0.0349492 |
| TPX2 | TPX2, microtubule-associated | -0.0348847 |
| CAVIN1 | caveolae associated protein 1 | -0.0347336 |
| ACER3 | alkaline ceramidase 3 | -0.0342316 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.034069 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.033929 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.033556 |
| GNAS | GNAS complex locus | -0.0334531 |
| RBM39 | RNA binding motif protein 39 | -0.0331796 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0331531 |
| DIAPH3 | diaphanous-related formin 3 | -0.0328646 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0327652 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0326949 |
| YBX1 | Y box binding protein 1 | -0.0323702 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0322122 |
| ERBIN | erbb2 interacting protein | -0.0322019 |
| RPLP0 | ribosomal protein, large, P0 | -0.0320888 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0319924 |
| ATG7 | autophagy related 7 | -0.0316607 |
| RDX | radixin | -0.0315796 |
| RANBP17 | RAN binding protein 17 | -0.0313874 |
| ENO1 | enolase 1, (alpha) | -0.0310578 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0308864 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0308541 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0305696 |
| OSMR | oncostatin M receptor | -0.0305239 |
| CENPF | centromere protein F, 350/400kDa | -0.0302613 |
| ANGPTL4 | angiopoietin-like 4 | -0.0299858 |
| RPL30 | ribosomal protein L30 | -0.0298805 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0291757 |
| ANLN | anillin, actin binding protein | -0.0290198 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289051 |
| SBF2 | SET binding factor 2 | -0.0288125 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0288084 |
| MKI67 | marker of proliferation Ki-67 | -0.0286476 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0283207 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0282991 |
| FBXO11 | F-box protein 11 | -0.0282125 |
| NF1 | neurofibromin 1 | -0.0280659 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0279532 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0274739 |
| WDR45B | WD repeat domain 45B | -0.0269433 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0268267 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0268169 |
| VCL | vinculin | -0.0268098 |
| AHNAK | AHNAK nucleoprotein | -0.0267198 |
| PYGL | phosphorylase, glycogen, liver | -0.0266309 |
| PTK2 | protein tyrosine kinase 2 | -0.0264275 |
| MEF2A | myocyte enhancer factor 2A | -0.0262976 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0260179 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0256891 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0256163 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0255988 |
| LAMB1 | laminin, beta 1 | -0.0255092 |
| RRBP1 | ribosome binding protein 1 | -0.0254327 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.025052 |
| ECT2 | epithelial cell transforming 2 | -0.0250337 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0248653 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0248631 |
