palmatine-2795 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the palmatine-2795 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX5 arachidonate 5-lipoxygenase
APOE apolipoprotein E
ARHGAP33 Rho GTPase activating protein 33
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASIC3 acid sensing (proton gated) ion channel 3
BCO1 beta-carotene oxygenase 1
BMP5 bone morphogenetic protein 5
C1ORF61 chromosome 1 open reading frame 61
CABIN1 calcineurin binding protein 1
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAV2 caveolin 2
CCNK cyclin K
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLDN1 claudin 1
CLN3 ceroid-lipofuscinosis, neuronal 3
CNTNAP2 contactin associated protein-like 2
DLK2 delta-like 2 homolog (Drosophila)
DNPEP aspartyl aminopeptidase
DOC2A double C2-like domains, alpha
DPYSL4 dihydropyrimidinase-like 4
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
EMC1 ER membrane protein complex subunit 1
EMILIN2 elastin microfibril interfacer 2
ERP44 endoplasmic reticulum protein 44
EVA1B eva-1 homolog B (C. elegans)
FMO5 flavin containing monooxygenase 5
FUZ fuzzy planar cell polarity protein
GK glycerol kinase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRK5 G protein-coupled receptor kinase 5
GYG2 glycogenin 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIPK3 homeodomain interacting protein kinase 3
IFNW1 interferon, omega 1
IQCC IQ motif containing C
ITGA10 integrin, alpha 10
ITGB6 integrin, beta 6
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCTD17 potassium channel tetramerization domain containing 17
KIAA1107 KIAA1107
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LIMCH1 LIM and calponin homology domains 1
LIN7B lin-7 homolog B (C. elegans)
LMF2 lipase maturation factor 2
LMNA lamin A/C
METTL16 methyltransferase like 16
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP3 matrix metallopeptidase 3
MYO1F myosin IF
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NOP16 NOP16 nucleolar protein
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUPR1 nuclear protein, transcriptional regulator, 1
OGFRL1 opioid growth factor receptor-like 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAUR plasminogen activator, urokinase receptor
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PML promyelocytic leukemia
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTMS parathymosin
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB6B RAB6B, member RAS oncogene family
RARA retinoic acid receptor, alpha
RB1 retinoblastoma 1
RNF19B ring finger protein 19B
RPAP1 RNA polymerase II associated protein 1
RYR1 ryanodine receptor 1 (skeletal)
SAG S-antigen; retina and pineal gland (arrestin)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMC4 structural maintenance of chromosomes 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1B small proline-rich protein 1B
STX7 syntaxin 7
TBC1D2 TBC1 domain family, member 2
THBS3 thrombospondin 3
TLDC1 TBC/LysM-associated domain containing 1
TRA T cell receptor alpha locus
TRAK1 trafficking protein, kinesin binding 1
UBXN6 UBX domain protein 6
WDFY3 WD repeat and FYVE domain containing 3
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF236 zinc finger protein 236
ZNF304 zinc finger protein 304
ZYX zyxin

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADCY7 adenylate cyclase 7
AHDC1 AT hook, DNA binding motif, containing 1
AMT aminomethyltransferase
APOD apolipoprotein D
ARMC4 armadillo repeat containing 4
ASB6 ankyrin repeat and SOCS box containing 6
BCAS1 breast carcinoma amplified sequence 1
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF73 chromosome 19 open reading frame 73
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CISH cytokine inducible SH2-containing protein
CLCN6 chloride channel, voltage-sensitive 6
CLEC16A C-type lectin domain family 16, member A
DGKE diacylglycerol kinase, epsilon 64kDa
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FAM188A family with sequence similarity 188, member A
FAM189A2 family with sequence similarity 189, member A2
FAM63A family with sequence similarity 63, member A
FCHO1 FCH domain only 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GFI1 growth factor independent 1 transcription repressor
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRTP1 growth hormone regulated TBC protein 1
GRWD1 glutamate-rich WD repeat containing 1
GSTTP1 glutathione S-transferase theta pseudogene 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H3E histone cluster 1, H3e
HOXC8 homeobox C8
HPS6 Hermansky-Pudlak syndrome 6
HYAL1 hyaluronoglucosaminidase 1
JUNB jun B proto-oncogene
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD7 potassium channel tetramerization domain containing 7
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRC23 leucine rich repeat containing 23
LRRC37A2 leucine rich repeat containing 37, member A2
LY6D lymphocyte antigen 6 complex, locus D
LY6G6C lymphocyte antigen 6 complex, locus G6C
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAV2 neuron navigator 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
NXPE3 neurexophilin and PC-esterase domain family, member 3
OSGIN1 oxidative stress induced growth inhibitor 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLH polymerase (DNA directed), eta
PTDSS2 phosphatidylserine synthase 2
PTPRU protein tyrosine phosphatase, receptor type, U
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS19 regulator of G-protein signaling 19
SENP7 SUMO1/sentrin specific peptidase 7
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLPI secretory leukocyte peptidase inhibitor
SMIM14 small integral membrane protein 14
SPON2 spondin 2, extracellular matrix protein
TBL1Y transducin (beta)-like 1, Y-linked
TCP10 t-complex 10
THRB thyroid hormone receptor, beta
TLN1 talin 1
TMC7 transmembrane channel-like 7
TMEM45A transmembrane protein 45A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOR4A torsin family 4, member A
TRIP10 thyroid hormone receptor interactor 10
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
WDR25 WD repeat domain 25
WDR91 WD repeat domain 91
ZBTB22 zinc finger and BTB domain containing 22
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT5 zinc finger, matrin-type 5
ZNF428 zinc finger protein 428
ZNF862 zinc finger protein 862