palmatine-4957 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the palmatine-4957 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMCX4 armadillo repeat containing, X-linked 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF7 activating transcription factor 7
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCKAR cholecystokinin A receptor
CD248 CD248 molecule, endosialin
CFAP70 cilia and flagella associated protein 70
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNN1 calponin 1, basic, smooth muscle
COL14A1 collagen, type XIV, alpha 1
CPNE7 copine VII
CTNS cystinosin, lysosomal cystine transporter
CXORF21 chromosome X open reading frame 21
DDIT3 DNA-damage-inducible transcript 3
DPF3 D4, zinc and double PHD fingers, family 3
EHD1 EH-domain containing 1
ERCC2 excision repair cross-complementation group 2
EXOSC1 exosome component 1
EXT1 exostosin glycosyltransferase 1
FAM134B family with sequence similarity 134, member B
FAM46C family with sequence similarity 46, member C
FBXO40 F-box protein 40
FLJ11292
FST follistatin
FXYD5 FXYD domain containing ion transport regulator 5
GHRHR growth hormone releasing hormone receptor
GJA8 gap junction protein, alpha 8, 50kDa
GLP1R glucagon-like peptide 1 receptor
GPR153 G protein-coupled receptor 153
GSTM5 glutathione S-transferase mu 5
HDAC7 histone deacetylase 7
HFE hemochromatosis
HIPK2 homeodomain interacting protein kinase 2
HRASLS HRAS-like suppressor
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBA inhibin, beta A
KIF21B kinesin family member 21B
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT19P2 keratin 19 pseudogene 2
LAT2 linker for activation of T cells family, member 2
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00597 long intergenic non-protein coding RNA 597
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MIER2 mesoderm induction early response 1, family member 2
MRPS18C mitochondrial ribosomal protein S18C
MT1G metallothionein 1G
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NCOR2 nuclear receptor corepressor 2
NEUROD1 neuronal differentiation 1
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOVA2 neuro-oncological ventral antigen 2
OLFML2A olfactomedin-like 2A
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDPN podoplanin
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PSCA prostate stem cell antigen
PURA purine-rich element binding protein A
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBBP9 retinoblastoma binding protein 9
RNF126P1 ring finger protein 126 pseudogene 1
SCAPER S-phase cyclin A-associated protein in the ER
SCN10A sodium channel, voltage gated, type X alpha subunit
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMG6 SMG6 nonsense mediated mRNA decay factor
SNTA1 syntrophin, alpha 1
SOX21 SRY (sex determining region Y)-box 21
SP100 SP100 nuclear antigen
SPON1 spondin 1, extracellular matrix protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSX3 synovial sarcoma, X breakpoint 3
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STARD8 StAR-related lipid transfer (START) domain containing 8
STEAP4 STEAP family member 4
TAAR5 trace amine associated receptor 5
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D2 TBC1 domain family, member 2
TBC1D22A TBC1 domain family, member 22A
TDRD3 tudor domain containing 3
TM4SF1 transmembrane 4 L six family member 1
TMCC2 transmembrane and coiled-coil domain family 2
TNC tenascin C
TP53I11 tumor protein p53 inducible protein 11
VN1R1 vomeronasal 1 receptor 1
VWA5A von Willebrand factor A domain containing 5A
ZFP2 ZFP2 zinc finger protein

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADCK3 aarF domain containing kinase 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG4A autophagy related 4A, cysteine peptidase
BSG basigin (Ok blood group)
CAMTA1 calmodulin binding transcription activator 1
CCDC6 coiled-coil domain containing 6
CCNT1 cyclin T1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEP85 centrosomal protein 85kDa
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CIDEC cell death-inducing DFFA-like effector c
CYB5R1 cytochrome b5 reductase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
EFNA3 ephrin-A3
EFNA4 ephrin-A4
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXL15 F-box and leucine-rich repeat protein 15
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GPR87 G protein-coupled receptor 87
GRWD1 glutamate-rich WD repeat containing 1
HMHA1 histocompatibility (minor) HA-1
HOXC10 homeobox C10
HOXC6 homeobox C6
HSPA1L heat shock 70kDa protein 1-like
ISYNA1 inositol-3-phosphate synthase 1
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
LYPD1 LY6/PLAUR domain containing 1
MAGOHB mago-nashi homolog B (Drosophila)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCRS1 microspherule protein 1
MED9 mediator complex subunit 9
METTL16 methyltransferase like 16
METTL2B methyltransferase like 2B
MOSPD3 motile sperm domain containing 3
MVD mevalonate (diphospho) decarboxylase
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NOSIP nitric oxide synthase interacting protein
NPY1R neuropeptide Y receptor Y1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUP62CL nucleoporin 62kDa C-terminal like
PARD6B par-6 family cell polarity regulator beta
PFAS phosphoribosylformylglycinamidine synthase
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIH1D1 PIH1 domain containing 1
PLAC8 placenta-specific 8
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POR P450 (cytochrome) oxidoreductase
PPAN peter pan homolog (Drosophila)
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
RIT1 Ras-like without CAAX 1
SCAND1 SCAN domain containing 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SDAD1 SDA1 domain containing 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC35E3 solute carrier family 35, member E3
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SOWAHC sosondowah ankyrin repeat domain family member C
SPRY2 sprouty homolog 2 (Drosophila)
SREK1IP1 SREK1-interacting protein 1
SSFA2 sperm specific antigen 2
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STX4 syntaxin 4
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTA T-cell leukemia translocation altered
TESK1 testis-specific kinase 1
TET3 tet methylcytosine dioxygenase 3
THOP1 thimet oligopeptidase 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3D tubulin, alpha 3d
UBXN8 UBX domain protein 8
WDR46 WD repeat domain 46
YIPF5 Yip1 domain family, member 5
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT5 zinc finger, matrin-type 5
ZNF574 zinc finger protein 574
ZNHIT2 zinc finger, HIT-type containing 2
ZNRD1-AS1 ZNRD1 antisense RNA 1