palmatine-6612 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the palmatine-6612 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
A4GALT alpha 1,4-galactosyltransferase
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACTN2 actinin, alpha 2
ADCK2 aarF domain containing kinase 2
ANGPT1 angiopoietin 1
APOC1 apolipoprotein C-I
ARG1 arginase 1
ARHGAP35 Rho GTPase activating protein 35
ARSD arylsulfatase D
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMPR1B bone morphogenetic protein receptor, type IB
BTG2 BTG family, member 2
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CEP41 centrosomal protein 41kDa
CERS4 ceramide synthase 4
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCN1 chloride channel, voltage-sensitive 1
CNGA1 cyclic nucleotide gated channel alpha 1
COL5A1 collagen, type V, alpha 1
CP ceruloplasmin (ferroxidase)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCLK1 doublecortin-like kinase 1
DGKG diacylglycerol kinase, gamma 90kDa
DHODH dihydroorotate dehydrogenase (quinone)
DPF3 D4, zinc and double PHD fingers, family 3
EFNA3 ephrin-A3
ELOVL2 ELOVL fatty acid elongase 2
EVI2A ecotropic viral integration site 2A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLRT2 fibronectin leucine rich transmembrane protein 2
FUT2 fucosyltransferase 2 (secretor status included)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GFI1 growth factor independent 1 transcription repressor
GLB1L galactosidase, beta 1-like
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GYPB glycophorin B (MNS blood group)
IL17RB interleukin 17 receptor B
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKA inositol-trisphosphate 3-kinase A
KIFC3 kinesin family member C3
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIN28A lin-28 homolog A (C. elegans)
LRP2 low density lipoprotein receptor-related protein 2
LTBP4 latent transforming growth factor beta binding protein 4
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MPL MPL proto-oncogene, thrombopoietin receptor
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NKX3-1 NK3 homeobox 1
NRF1 nuclear respiratory factor 1
NRTN neurturin
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PADI2 peptidyl arginine deiminase, type II
PALM paralemmin
PDGFA platelet-derived growth factor alpha polypeptide
PHLDB1 pleckstrin homology-like domain, family B, member 1
PML promyelocytic leukemia
PPARA peroxisome proliferator-activated receptor alpha
PQBP1 polyglutamine binding protein 1
PTCRA pre T-cell antigen receptor alpha
PTN pleiotrophin
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB33A RAB33A, member RAS oncogene family
RASAL2 RAS protein activator like 2
RGS5 regulator of G-protein signaling 5
RNGTT RNA guanylyltransferase and 5'-phosphatase
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3BP2 SH3-domain binding protein 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC22A14 solute carrier family 22, member 14
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOS2 son of sevenless homolog 2 (Drosophila)
STAT4 signal transducer and activator of transcription 4
SYNJ1 synaptojanin 1
TCF3 transcription factor 3
THAP9 THAP domain containing 9
TLK1 tousled-like kinase 1
TLR2 toll-like receptor 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSC2 tuberous sclerosis 2
TTC12 tetratricopeptide repeat domain 12
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UHRF1BP1L UHRF1 binding protein 1-like
WT1-AS WT1 antisense RNA
YBX2 Y box binding protein 2
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACVR2B activin A receptor, type IIB
ALG12 ALG12, alpha-1,6-mannosyltransferase
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
C16ORF62 chromosome 16 open reading frame 62
CBX4 chromobox homolog 4
CDON cell adhesion associated, oncogene regulated
CINP cyclin-dependent kinase 2 interacting protein
CORT cortistatin
CREB5 cAMP responsive element binding protein 5
DBF4B DBF4 zinc finger B
DDN dendrin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DSPP dentin sialophosphoprotein
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXL15 F-box and leucine-rich repeat protein 15
FBXO2 F-box protein 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALK1 galactokinase 1
GCHFR GTP cyclohydrolase I feedback regulator
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H2AFJ H2A histone family, member J
HAMP hepcidin antimicrobial peptide
HINFP histone H4 transcription factor
HIST1H2AM histone cluster 1, H2am
HIST1H2BJ histone cluster 1, H2bj
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
IFI44L interferon-induced protein 44-like
IL12B interleukin 12B
IPO8 importin 8
JMJD4 jumonji domain containing 4
KDM7A lysine (K)-specific demethylase 7A
LAMC3 laminin, gamma 3
LINS lines homolog (Drosophila)
MNX1 motor neuron and pancreas homeobox 1
MXD3 MAX dimerization protein 3
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NME5 NME/NM23 family member 5
NOL6 nucleolar protein 6 (RNA-associated)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
ONECUT2 one cut homeobox 2
OSMR oncostatin M receptor
PADI1 peptidyl arginine deiminase, type I
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDZK1 PDZ domain containing 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11B RAB11B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RPGRIP1L RPGRIP1-like
RPP25 ribonuclease P/MRP 25kDa subunit
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SCG2 secretogranin II
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SIX3 SIX homeobox 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SND1-IT1 SND1 intronic transcript 1
SPAG7 sperm associated antigen 7
SPRYD7 SPRY domain containing 7
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMC5 transmembrane channel-like 5
TMEM212 transmembrane protein 212
TMEM8A transmembrane protein 8A
TPRA1 transmembrane protein, adipocyte asscociated 1
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP20 ubiquitin specific peptidase 20
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFHX3 zinc finger homeobox 3
ZNF280D zinc finger protein 280D
ZNF415 zinc finger protein 415
ZNF446 zinc finger protein 446
ZNF862 zinc finger protein 862