pam Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description peptidylglycine alpha-amidating monooxygenase|This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5066)
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Genes

10 genes co-occuring with the biological term pam in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NR1D1 nuclear receptor subfamily 1, group D, member 1
PAM peptidylglycine alpha-amidating monooxygenase
PLG plasminogen
SCN4A sodium channel, voltage gated, type IV alpha subunit
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SSB Sjogren syndrome antigen B (autoantigen La)
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2