pancreatitis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Inflammation of the pancreas.|INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. (Experimental Factor Ontology, EFO_0000278)
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Genes

32 genes associated with the disease pancreatitis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
C18ORF8 chromosome 18 open reading frame 8
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CTRC chymotrypsin C (caldecrin)
CXCL8 chemokine (C-X-C motif) ligand 8
F5 coagulation factor V (proaccelerin, labile factor)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA1B heat shock 70kDa protein 1B
IFNG interferon, gamma
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
KRT8 keratin 8, type II
LTA lymphotoxin alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
PRSS1 protease, serine, 1 (trypsin 1)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOD2 superoxide dismutase 2, mitochondrial
SPINK1 serine peptidase inhibitor, Kazal type 1
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor