pancreatitis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Inflammation of the pancreas.|INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. (Experimental Factor Ontology, EFO_0000278)
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Genes

181 genes co-occuring with the biological term pancreatitis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACE angiotensin I converting enzyme
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AHSG alpha-2-HS-glycoprotein
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMY2A amylase, alpha 2A (pancreatic)
ANGPT2 angiopoietin 2
APOA5 apolipoprotein A-V
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AVP arginine vasopressin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BRAF B-Raf proto-oncogene, serine/threonine kinase
CA2 carbonic anhydrase II
CALCA calcitonin-related polypeptide alpha
CASR calcium-sensing receptor
CCL1 chemokine (C-C motif) ligand 1
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCR8 chemokine (C-C motif) receptor 8
CD14 CD14 molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEL carboxyl ester lipase
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGA chromogranin A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN2 claudin 2
CMKLR1 chemerin chemokine-like receptor 1
COMT catechol-O-methyltransferase
CPA1 carboxypeptidase A1 (pancreatic)
CRISP3 cysteine-rich secretory protein 3
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTRC chymotrypsin C (caldecrin)
CTSB cathepsin B
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEFB1 defensin, beta 1
DEFB104A defensin, beta 104A
EDN1 endothelin 1
EDNRA endothelin receptor type A
EGF epidermal growth factor
ELANE elastase, neutrophil expressed
ENG endoglin
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FPR2 formyl peptide receptor 2
GAS6 growth arrest-specific 6
GCG glucagon
GCH1 GTP cyclohydrolase 1
GDF15 growth differentiation factor 15
GGT1 gamma-glutamyltransferase 1
GP2 glycoprotein 2 (zymogen granule membrane)
GPR32 G protein-coupled receptor 32
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
HSPA1B heat shock 70kDa protein 1B
HSPB1 heat shock 27kDa protein 1
HSPE1 heat shock 10kDa protein 1
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IGHE immunoglobulin heavy constant epsilon
IL10 interleukin 10
IL18 interleukin 18
IL1B interleukin 1, beta
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL33R interleukin 33 receptor
IL6 interleukin 6
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LAMP2 lysosomal-associated membrane protein 2
LCN2 lipocalin 2
LEP leptin
LIPC lipase, hepatic
LPL lipoprotein lipase
LTA lymphotoxin alpha
LTF lactotransferrin
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MUC7 mucin 7, secreted
MYO9B myosin IXB
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
NPTX2 neuronal pentraxin II
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDGFB platelet-derived growth factor beta polypeptide
PNLIP pancreatic lipase
PNLIPRP2 pancreatic lipase-related protein 2
PON1 paraoxonase 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPY pancreatic polypeptide
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
REG1A regenerating islet-derived 1 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RHOA ras homolog family member A
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAA1 serum amyloid A1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SHH sonic hedgehog
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TAC1 tachykinin, precursor 1
TF transferrin
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THPO thrombopoietin
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TPST2 tyrosylprotein sulfotransferase 2
TREM1 triggering receptor expressed on myeloid cells 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
VEGFA vascular endothelial growth factor A
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZEB2 zinc finger E-box binding homeobox 2