pancytopenia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

187 genes co-occuring with the disease pancytopenia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.89499
CD34 CD34 molecule 1.41534
TPMT thiopurine S-methyltransferase 1.40745
FTH1 ferritin, heavy polypeptide 1 1.3952
FTL ferritin, light polypeptide 1.3952
THPO thrombopoietin 1.37861
NAAA N-acylethanolamine acid amidase 1.33894
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.32367
FANCA Fanconi anemia, complementation group A 1.28523
NCAM1 neural cell adhesion molecule 1 1.2495
MPL MPL proto-oncogene, thrombopoietin receptor 1.24906
CD5 CD5 molecule 1.20959
CD4 CD4 molecule 1.15368
CD19 CD19 molecule 1.15283
CD33 CD33 molecule 1.13543
RARS arginyl-tRNA synthetase 1.12319
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.12193
CSF3 colony stimulating factor 3 (granulocyte) 1.1051
CD59 CD59 molecule, complement regulatory protein 1.1051
PRF1 perforin 1 (pore forming protein) 1.07908
CD7 CD7 molecule 1.05597
IL3 interleukin 3 0.997814
GPR156 G protein-coupled receptor 156 0.98011
TCN2 transcobalamin II 0.977585
IL2RA interleukin 2 receptor, alpha 0.974642
SMR3B submaxillary gland androgen regulated protein 3B 0.947019
FANCC Fanconi anemia, complementation group C 0.942443
AGO2 argonaute RISC catalytic component 2 0.929173
UNC13D unc-13 homolog D (C. elegans) 0.921323
DKC1 dyskeratosis congenita 1, dyskerin 0.918436
GIF gastric intrinsic factor (vitamin B synthesis) 0.894589
ACPP acid phosphatase, prostate 0.892948
MNX1 motor neuron and pancreas homeobox 1 0.856087
B3GAT1 beta-1,3-glucuronyltransferase 1 0.845031
RAB27A RAB27A, member RAS oncogene family 0.843392
SH2D1A SH2 domain containing 1A 0.834788
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.822897
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.806077
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.797462
CD79A CD79a molecule, immunoglobulin-associated alpha 0.784345
LYZ lysozyme 0.783526
FANCD2 Fanconi anemia, complementation group D2 0.777795
HP haptoglobin 0.771252
HPR haptoglobin-related protein 0.764718
MPO myeloperoxidase 0.761454
STX11 syntaxin 11 0.751271
ALPP alkaline phosphatase, placental 0.750457
RGMA repulsive guidance molecule family member a 0.740705
ALPPL2 alkaline phosphatase, placental-like 2 0.732191
ALPL alkaline phosphatase, liver/bone/kidney 0.730976
SBDS Shwachman-Bodian-Diamond syndrome 0.709975
FLT3 fms-related tyrosine kinase 3 0.699116
CLCN7 chloride channel, voltage-sensitive 7 0.688291
GBA glucosidase, beta, acid 0.683493
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.654858
KRT83 keratin 83, type II 0.648928
MCEE methylmalonyl CoA epimerase 0.646953
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 0.642615
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.626103
HLA-C major histocompatibility complex, class I, C 0.625319
CHL1 cell adhesion molecule L1-like 0.624927
IFNA1 interferon, alpha 1 0.6214
CLASP2 cytoplasmic linker associated protein 2 0.613183
FANCF Fanconi anemia, complementation group F 0.595233
IVL involucrin 0.594454
CD68 CD68 molecule 0.581996
RPL27A ribosomal protein L27a 0.57655
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 0.575383
RARA retinoic acid receptor, alpha 0.57305
IL2 interleukin 2 0.571884
GATA2 GATA binding protein 2 0.565666
TNF tumor necrosis factor 0.562946
OSTM1 osteopetrosis associated transmembrane protein 1 0.555568
FANCE Fanconi anemia, complementation group E 0.550134
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.549747
PRODH proline dehydrogenase (oxidase) 1 0.545868
NFRKB nuclear factor related to kappaB binding protein 0.520731
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.51919
C8B complement component 8, beta polypeptide 0.517265
HOXB4 homeobox B4 0.517265
EPO erythropoietin 0.513033
MIR4315-1 microRNA 4315-1 0.499614
MIR4315-2 microRNA 4315-2 0.499614
SERINC5 serine incorporator 5 0.494648
CRP C-reactive protein, pentraxin-related 0.490835
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 0.489311
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.483604
CP ceruloplasmin (ferroxidase) 0.479047
ALB albumin 0.479047
BCR breakpoint cluster region 0.474877
NHEJ1 nonhomologous end-joining factor 1 0.468819
SP110 SP110 nuclear body protein 0.465416
LIG4 ligase IV, DNA, ATP-dependent 0.463527
CLEC5A C-type lectin domain family 5, member A 0.458996
MYO5A myosin VA (heavy chain 12, myoxin) 0.455224
F2 coagulation factor II (thrombin) 0.445805
IL6 interleukin 6 0.440914
TALDO1 transaldolase 1 0.436778
CD320 CD320 molecule 0.42739
IFNA10 interferon, alpha 10 0.425514
F3 coagulation factor III (thromboplastin, tissue factor) 0.42364
KTN1 kinectin 1 (kinesin receptor) 0.421765
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.418768
CD52 CD52 molecule 0.415024
EPAS1 endothelial PAS domain protein 1 0.409787
CD22 CD22 molecule 0.398962
RUNX1 runt-related transcription factor 1 0.398216
FHL2 four and a half LIM domains 2 0.396353
MOBP myelin-associated oligodendrocyte basic protein 0.381852
HOXA9 homeobox A9 0.372958
ADA adenosine deaminase 0.359289
EMILIN1 elastin microfibril interfacer 1 0.354868
IL3RA interleukin 3 receptor, alpha (low affinity) 0.353027
AHSG alpha-2-HS-glycoprotein 0.350084
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.348614
CD48 CD48 molecule 0.347511
GYPA glycophorin A (MNS blood group) 0.344207
HMP19 HMP19 protein 0.33651
ITSN1 intersectin 1 (SH3 domain protein) 0.33651
S100A9 S100 calcium binding protein A9 0.323365
MUT methylmalonyl CoA mutase 0.321909
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.320454
CLC Charcot-Leyden crystal galectin 0.319726
STXBP2 syntaxin binding protein 2 0.317909
SAA1 serum amyloid A1 0.316456
PGK1 phosphoglycerate kinase 1 0.312827
CD38 CD38 molecule 0.310652
MIXL1 Mix paired-like homeobox 0.310652
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.30848
MGMT O-6-methylguanine-DNA methyltransferase 0.306672
CXXC5 CXXC finger protein 5 0.291898
RAD51B RAD51 paralog B 0.288668
MMD monocyte to macrophage differentiation-associated 0.28831
MEIS1 Meis homeobox 1 0.277584
LDHA lactate dehydrogenase A 0.277584
EPOR erythropoietin receptor 0.277227
FASLG Fas ligand (TNF superfamily, member 6) 0.276514
FAM131C family with sequence similarity 131, member C 0.275801
NUP98 nucleoporin 98kDa 0.268687
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.268687
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.267977
FANCG Fanconi anemia, complementation group G 0.267622
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.259477
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.255946
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.255594
DOT1L DOT1-like histone H3K79 methyltransferase 0.242245
DNTT DNA nucleotidylexotransferase 0.241895
CYGB cytoglobin 0.241895
TBX21 T-box 21 0.240497
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.240148
HDAC7 histone deacetylase 7 0.229024
F8 coagulation factor VIII, procoagulant component 0.227297
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.226262
CD163 CD163 molecule 0.226262
GSR glutathione reductase 0.225229
FSCN3 fascin actin-bundling protein 3, testicular 0.224884
CYTIP cytohesin 1 interacting protein 0.22454
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.216672
RAD50 RAD50 homolog (S. cerevisiae) 0.213959
SLC46A1 solute carrier family 46 (folate transporter), member 1 0.210253
GDF6 growth differentiation factor 6 0.203604
JAK2 Janus kinase 2 0.20229
FSCN2 fascin actin-bundling protein 2, retinal 0.200982
F11 coagulation factor XI 0.196779
IVD isovaleryl-CoA dehydrogenase 0.19582
ARTN artemin 0.19582
TOP3A topoisomerase (DNA) III alpha 0.193915
KAT8 K(lysine) acetyltransferase 8 0.1936
HOXD9 homeobox D9 0.190476
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.18591
CCL3 chemokine (C-C motif) ligand 3 0.183835
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.182666
LAT linker for activation of T cells 0.18151
POU3F4 POU class 3 homeobox 4 0.178403
NLRC4 NLR family, CARD domain containing 4 0.177029
ZC3H12D zinc finger CCCH-type containing 12D 0.173832
PTPRC protein tyrosine phosphatase, receptor type, C 0.173832
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.171535
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.16933
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.168381
CDA cytidine deaminase 0.166095
PYCARD PYD and CARD domain containing 0.165874
HLA-B major histocompatibility complex, class I, B 0.165655
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.164786
GGT1 gamma-glutamyltransferase 1 0.163111
DHFR dihydrofolate reductase 0.161912
ZFY zinc finger protein, Y-linked 0.160761