papaverine-2747 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the papaverine-2747 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRL1 adhesion G protein-coupled receptor L1
ATP10A ATPase, class V, type 10A
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BCAP29 B-cell receptor-associated protein 29
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BGN biglycan
C16ORF45 chromosome 16 open reading frame 45
C1QB complement component 1, q subcomponent, B chain
CCDC71 coiled-coil domain containing 71
CCNG2 cyclin G2
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CIC capicua transcriptional repressor
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CSF1R colony stimulating factor 1 receptor
CT62 cancer/testis antigen 62
CYLD cylindromatosis (turban tumor syndrome)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRD2 dopamine receptor D2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
EVA1B eva-1 homolog B (C. elegans)
FBLN1 fibulin 1
FHL3 four and a half LIM domains 3
FKBP8 FK506 binding protein 8, 38kDa
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HAP1 huntingtin-associated protein 1
HCRP1 hepatocellular carcinoma-related HCRP1
HMG20B high mobility group 20B
HOMER3 homer scaffolding protein 3
ICA1 islet cell autoantigen 1, 69kDa
IFNA14 interferon, alpha 14
IL11 interleukin 11
IL1B interleukin 1, beta
IL4R interleukin 4 receptor
KAT6A K(lysine) acetyltransferase 6A
KAZN kazrin, periplakin interacting protein
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LARP4B La ribonucleoprotein domain family, member 4B
LHX2 LIM homeobox 2
LYST lysosomal trafficking regulator
MAGEA6 melanoma antigen family A6
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1A microtubule-associated protein 1A
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP11 matrix metallopeptidase 11
MUC3B mucin 3B, cell surface associated
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDRG2 NDRG family member 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPR2 natriuretic peptide receptor 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NYX nyctalopin
OSBPL10 oxysterol binding protein-like 10
PAWR PRKC, apoptosis, WT1, regulator
PER1 period circadian clock 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
POU5F1B POU class 5 homeobox 1B
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRODH2 proline dehydrogenase (oxidase) 2
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RGS10 regulator of G-protein signaling 10
RPL7 ribosomal protein L7
RPS4Y1 ribosomal protein S4, Y-linked 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SHANK1 SH3 and multiple ankyrin repeat domains 1
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMYD2 SET and MYND domain containing 2
SNCAIP synuclein, alpha interacting protein
SPAG8 sperm associated antigen 8
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSTR5 somatostatin receptor 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
STX7 syntaxin 7
THBS3 thrombospondin 3
TMEM45A transmembrane protein 45A
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WIPF1 WAS/WASL interacting protein family, member 1
YIPF4 Yip1 domain family, member 4
ZER1 zyg-11 related, cell cycle regulator
ZNF117 zinc finger protein 117
ZNF384 zinc finger protein 384
ZNF516 zinc finger protein 516

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ADCY6 adenylate cyclase 6
ADM adrenomedullin
AKAP12 A kinase (PRKA) anchor protein 12
ARHGAP11A Rho GTPase activating protein 11A
ARL4A ADP-ribosylation factor-like 4A
BCL9 B-cell CLL/lymphoma 9
BCORL1 BCL6 corepressor-like 1
BFSP1 beaded filament structural protein 1, filensin
BRPF1 bromodomain and PHD finger containing, 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C3ORF52 chromosome 3 open reading frame 52
C5AR2 complement component 5a receptor 2
CALCOCO1 calcium binding and coiled-coil domain 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CENPB centromere protein B, 80kDa
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCLRE1A DNA cross-link repair 1A
DSCAM Down syndrome cell adhesion molecule
ELOVL4 ELOVL fatty acid elongase 4
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM188A family with sequence similarity 188, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FIP1L1 factor interacting with PAPOLA and CPSF1
FJX1 four jointed box 1 (Drosophila)
FOLR1 folate receptor 1 (adult)
FPGS folylpolyglutamate synthase
GALT galactose-1-phosphate uridylyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H4F histone cluster 1, H4f
HMOX1 heme oxygenase 1
HSPA1L heat shock 70kDa protein 1-like
IFT22 intraflagellar transport 22
IL22 interleukin 22
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KLHL26 kelch-like family member 26
KPTN kaptin (actin binding protein)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYPD1 LY6/PLAUR domain containing 1
LYPD3 LY6/PLAUR domain containing 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGOHB mago-nashi homolog B (Drosophila)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MITF microphthalmia-associated transcription factor
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
MYO1F myosin IF
NCS1 neuronal calcium sensor 1
NHEJ1 nonhomologous end-joining factor 1
OGFRL1 opioid growth factor receptor-like 1
ONECUT2 one cut homeobox 2
PAIP2B poly(A) binding protein interacting protein 2B
PCDHA9 protocadherin alpha 9
PDIA3 protein disulfide isomerase family A, member 3
PGPEP1 pyroglutamyl-peptidase I
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G10 phospholipase A2, group X
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RNF43 ring finger protein 43
RPAP2 RNA polymerase II associated protein 2
SCAI suppressor of cancer cell invasion
SCUBE2 signal peptide, CUB domain, EGF-like 2
SIX1 SIX homeobox 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SRD5A3 steroid 5 alpha-reductase 3
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STX1A syntaxin 1A (brain)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMPRSS3 transmembrane protease, serine 3
TMSB15A thymosin beta 15a
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM16 tripartite motif containing 16
TSPAN5 tetraspanin 5
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZC3H3 zinc finger CCCH-type containing 3
ZNF250 zinc finger protein 250
ZNF365 zinc finger protein 365
ZNF480 zinc finger protein 480
ZNF544 zinc finger protein 544
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZSCAN31 zinc finger and SCAN domain containing 31