papaverine-5769 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the papaverine-5769 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADGRB2 adhesion G protein-coupled receptor B2
ADRBK2 adrenergic, beta, receptor kinase 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ALPK1 alpha-kinase 1
ARNT aryl hydrocarbon receptor nuclear translocator
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CD79B CD79b molecule, immunoglobulin-associated beta
CDC14B cell division cycle 14B
CDHR2 cadherin-related family member 2
CELA2A chymotrypsin-like elastase family, member 2A
CLCN7 chloride channel, voltage-sensitive 7
CLDN10 claudin 10
CLMN calmin (calponin-like, transmembrane)
COL6A1 collagen, type VI, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPPED1 calcineurin-like phosphoesterase domain containing 1
CXORF21 chromosome X open reading frame 21
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DHRS9 dehydrogenase/reductase (SDR family) member 9
DOK2 docking protein 2, 56kDa
DUSP1 dual specificity phosphatase 1
DZIP1 DAZ interacting zinc finger protein 1
EDN1 endothelin 1
FABP3 fatty acid binding protein 3, muscle and heart
FOXG1 forkhead box G1
GGT1 gamma-glutamyltransferase 1
GK glycerol kinase
GNRHR gonadotropin-releasing hormone receptor
GPR85 G protein-coupled receptor 85
GPSM3 G-protein signaling modulator 3
HDAC11 histone deacetylase 11
HHAT hedgehog acyltransferase
HIP1 huntingtin interacting protein 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HOMER3 homer scaffolding protein 3
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICOSLG inducible T-cell co-stimulator ligand
IGF1R insulin-like growth factor 1 receptor
IGHM immunoglobulin heavy constant mu
IL11 interleukin 11
ING2 inhibitor of growth family, member 2
ISG20 interferon stimulated exonuclease gene 20kDa
KLK2 kallikrein-related peptidase 2
KRT2 keratin 2, type II
MAPK8 mitogen-activated protein kinase 8
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPT microtubule-associated protein tau
MBNL2 muscleblind-like splicing regulator 2
MED25 mediator complex subunit 25
MFAP3 microfibrillar-associated protein 3
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTRF1L mitochondrial translational release factor 1-like
MUC8 mucin 8
NEB nebulin
NUDC nudC nuclear distribution protein
ONECUT2 one cut homeobox 2
PADI2 peptidyl arginine deiminase, type II
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKCA protein kinase C, alpha
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVT1 Pvt1 oncogene (non-protein coding)
RAB6A RAB6A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RIF1 replication timing regulatory factor 1
RIMS3 regulating synaptic membrane exocytosis 3
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPS4Y1 ribosomal protein S4, Y-linked 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERHL2 serine hydrolase-like 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC22A14 solute carrier family 22, member 14
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
STS steroid sulfatase (microsomal), isozyme S
TCF15 transcription factor 15 (basic helix-loop-helix)
TMF1 TATA element modulatory factor 1
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TP63 tumor protein p63
TRD T cell receptor delta locus
TTC12 tetratricopeptide repeat domain 12
UBE2I ubiquitin-conjugating enzyme E2I
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF224 zinc finger protein 224
ZNF529 zinc finger protein 529
ZNF550 zinc finger protein 550

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADRB2 adrenoceptor beta 2, surface
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAHCC1 BAH domain and coiled-coil containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BEX1 brain expressed, X-linked 1
C17ORF53 chromosome 17 open reading frame 53
C1RL complement component 1, r subcomponent-like
C3ORF18 chromosome 3 open reading frame 18
C9ORF3 chromosome 9 open reading frame 3
C9ORF40 chromosome 9 open reading frame 40
CCDC68 coiled-coil domain containing 68
CCDC71 coiled-coil domain containing 71
CCNO cyclin O
CD3EAP CD3e molecule, epsilon associated protein
CD82 CD82 molecule
CES3 carboxylesterase 3
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CYB5R2 cytochrome b5 reductase 2
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAH17 dynein, axonemal, heavy chain 17
DNAH7 dynein, axonemal, heavy chain 7
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
EYA4 EYA transcriptional coactivator and phosphatase 4
FMO4 flavin containing monooxygenase 4
FMOD fibromodulin
FUZ fuzzy planar cell polarity protein
GBX2 gastrulation brain homeobox 2
GPATCH3 G patch domain containing 3
GRPR gastrin-releasing peptide receptor
HDAC9 histone deacetylase 9
HIRA histone cell cycle regulator
HIST1H3G histone cluster 1, H3g
HOXC11 homeobox C11
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT54 intraflagellar transport 54
IL2 interleukin 2
IQCG IQ motif containing G
KIF20A kinesin family member 20A
KRT15 keratin 15, type I
KRT9 keratin 9, type I
LOC257152 uncharacterized LOC257152
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
LYRM9 LYR motif containing 9
MMP3 matrix metallopeptidase 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
NID2 nidogen 2 (osteonidogen)
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCOLCE procollagen C-endopeptidase enhancer
PDE12 phosphodiesterase 12
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLXNB3 plexin B3
POMT2 protein-O-mannosyltransferase 2
POU3F2 POU class 3 homeobox 2
PRSS22 protease, serine, 22
RANBP17 RAN binding protein 17
RUSC2 RUN and SH3 domain containing 2
SCARA3 scavenger receptor class A, member 3
SCG2 secretogranin II
SCG5 secretogranin V
SDC3 syndecan 3
SLC46A3 solute carrier family 46, member 3
SPEG SPEG complex locus
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
SUGCT succinyl-CoA:glutarate-CoA transferase
THRB thyroid hormone receptor, beta
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRABD TraB domain containing
TRAF2 TNF receptor-associated factor 2
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UGT8 UDP glycosyltransferase 8
VASH1 vasohibin 1
WDR33 WD repeat domain 33
YPEL1 yippee-like 1 (Drosophila)
ZNF205 zinc finger protein 205
ZNF492 zinc finger protein 492