papaverine-6245 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the papaverine-6245 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACTN4 actinin, alpha 4
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
ADRBK1 adrenergic, beta, receptor kinase 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP26 Rho GTPase activating protein 26
ATP11A ATPase, class VI, type 11A
ATP13A2 ATPase type 13A2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAIAP3 BAI1-associated protein 3
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CABIN1 calcineurin binding protein 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMKMT calmodulin-lysine N-methyltransferase
CCP110 centriolar coiled coil protein 110kDa
CENPT centromere protein T
CEP97 centrosomal protein 97kDa
CLK1 CDC-like kinase 1
CRELD1 cysteine-rich with EGF-like domains 1
CSHL1 chorionic somatomammotropin hormone-like 1
CTC1 CTS telomere maintenance complex component 1
DDIT3 DNA-damage-inducible transcript 3
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DLX4 distal-less homeobox 4
DNPEP aspartyl aminopeptidase
EGR3 early growth response 3
EPHX2 epoxide hydrolase 2, cytoplasmic
EPS8L1 EPS8-like 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM134B family with sequence similarity 134, member B
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPC3 glypican 3
HMG20A high mobility group 20A
HOMER3 homer scaffolding protein 3
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNIP1 Kv channel interacting protein 1
KIAA0040 KIAA0040
KLF13 Kruppel-like factor 13
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
KRT13 keratin 13, type I
LGALS2 lectin, galactoside-binding, soluble, 2
LMBR1L limb development membrane protein 1-like
LPIN2 lipin 2
LPPR2 lipid phosphate phosphatase-related protein type 2
MANBA mannosidase, beta A, lysosomal
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MET MET proto-oncogene, receptor tyrosine kinase
MID1 midline 1
MST1 macrophage stimulating 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NADK NAD kinase
NDRG2 NDRG family member 2
NFRKB nuclear factor related to kappaB binding protein
NLGN1 neuroligin 1
NRSN2 neurensin 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PGR progesterone receptor
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCE1 phospholipase C, epsilon 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRICKLE3 prickle homolog 3 (Drosophila)
PTGIS prostaglandin I2 (prostacyclin) synthase
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RHOQ ras homolog family member Q
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SFXN3 sideroflexin 3
SLC22A14 solute carrier family 22, member 14
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SPPL2B signal peptide peptidase like 2B
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STRN striatin, calmodulin binding protein
SYBU syntabulin (syntaxin-interacting)
TICAM1 toll-like receptor adaptor molecule 1
TMEM259 transmembrane protein 259
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRD T cell receptor delta locus
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UPK3B uroplakin 3B
VAMP4 vesicle-associated membrane protein 4
VAX2 ventral anterior homeobox 2
WDTC1 WD and tetratricopeptide repeats 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZHX3 zinc fingers and homeoboxes 3
ZNF165 zinc finger protein 165
ZNF277 zinc finger protein 277

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AEN apoptosis enhancing nuclease
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASPHD1 aspartate beta-hydroxylase domain containing 1
BAX BCL2-associated X protein
C11ORF95 chromosome 11 open reading frame 95
C17ORF80 chromosome 17 open reading frame 80
C1ORF35 chromosome 1 open reading frame 35
CAPRIN2 caprin family member 2
CENPC centromere protein C
CIDEB cell death-inducing DFFA-like effector b
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
DBR1 debranching RNA lariats 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF5A2 eukaryotic translation initiation factor 5A2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM172A family with sequence similarity 172, member A
FBRS fibrosin
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H2AG histone cluster 1, H2ag
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3IP1 immediate early response 3 interacting protein 1
INO80D INO80 complex subunit D
KAT2A K(lysine) acetyltransferase 2A
KIAA0355 KIAA0355
KRI1 KRI1 homolog (S. cerevisiae)
LAMB3 laminin, beta 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBIP MAP3K12 binding inhibitory protein 1
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NCAM2 neural cell adhesion molecule 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARD6A par-6 family cell polarity regulator alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PDIA3 protein disulfide isomerase family A, member 3
PECR peroxisomal trans-2-enoyl-CoA reductase
PFDN6 prefoldin subunit 6
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPAN peter pan homolog (Drosophila)
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PTTG3P pituitary tumor-transforming 3, pseudogene
RCOR3 REST corepressor 3
RNF39 ring finger protein 39
RPL13P5 ribosomal protein L13 pseudogene 5
RUFY2 RUN and FYVE domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SH2D4A SH2 domain containing 4A
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC16A6 solute carrier family 16, member 6
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC46A3 solute carrier family 46, member 3
STARD13 StAR-related lipid transfer (START) domain containing 13
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
TEAD3 TEA domain family member 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPST2 tyrosylprotein sulfotransferase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC23 tetratricopeptide repeat domain 23
TTC26 tetratricopeptide repeat domain 26
TXNIP thioredoxin interacting protein
UBQLN4 ubiquilin 4
VAV1 vav 1 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFC vascular endothelial growth factor C
WLS wntless Wnt ligand secretion mediator
ZBTB3 zinc finger and BTB domain containing 3
ZBTB38 zinc finger and BTB domain containing 38
ZNF219 zinc finger protein 219
ZNF273 zinc finger protein 273
ZNF652 zinc finger protein 652
ZXDC ZXD family zinc finger C