pappa Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description pregnancy-associated plasma protein A, pappalysin 1|This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5069)
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Genes

28 genes co-occuring with the biological term pappa in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAM12 ADAM metallopeptidase domain 12
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
ALB albumin
CGB chorionic gonadotropin, beta polypeptide
CRP C-reactive protein, pentraxin-related
GDF15 growth differentiation factor 15
HMGB1 high mobility group box 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
INHA inhibin, alpha
INS insulin
LGALS13 lectin, galactoside-binding, soluble, 13
MIR214 microRNA 214
MIR490 microRNA 490
MMP2 matrix metallopeptidase 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PPARG peroxisome proliferator-activated receptor gamma
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SCARB1 scavenger receptor class B, member 1
SELE selectin E
TNFRSF4 tumor necrosis factor receptor superfamily, member 4