paralysis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Paralysis of voluntary muscles means loss of contraction due to interruption of one or more motor pathways from the brain to the muscle fibers. Although the word paralysis is often used interchangeably to mean either complete or partial loss of muscle strength, it is preferable to use paralysis or plegia for complete or severe loss of muscle strength, and paresis for partial or slight loss. Motor paralysis results from deficits of the upper motor neurons (corticospinal, corticobulbar, or subcorticospinal). Motor paralysis is often accompanied by an impairment in the facility of movement. (Human Phenotype Ontology, HP_0003470)
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Genes

26 genes co-occuring with the biological term paralysis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
BCHE butyrylcholinesterase
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CHD7 chromodomain helicase DNA binding protein 7
CLDN19 claudin 19
FUS FUS RNA binding protein
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
IL16 interleukin 16
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MPZ myelin protein zero
NEFL neurofilament, light polypeptide
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PRX periaxin
SCN4A sodium channel, voltage gated, type IV alpha subunit
SEPT9 septin 9
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SOD1 superoxide dismutase 1, soluble
TARDBP TAR DNA binding protein
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRPV4 transient receptor potential cation channel, subfamily V, member 4
VEGFA vascular endothelial growth factor A