paranodal junction Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath. (Gene Ontology, GO_0033010)
External Link http://amigo.geneontology.org/amigo/term/GO:0033010
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Genes

4 proteins localized to the paranodal junction cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
JAM3 junctional adhesion molecule 3
MARVELD2 MARVEL domain containing 2
NFASC neurofascin
SIRT2 sirtuin 2