Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the parbendazole-4357 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADCY9 | adenylate cyclase 9 |
AFF3 | AF4/FMR2 family, member 3 |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
ANK1 | ankyrin 1, erythrocytic |
APOL6 | apolipoprotein L, 6 |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
ATN1 | atrophin 1 |
BIN1 | bridging integrator 1 |
BTBD7 | BTB (POZ) domain containing 7 |
C19ORF26 | chromosome 19 open reading frame 26 |
C7ORF69 | chromosome 7 open reading frame 69 |
CALB1 | calbindin 1, 28kDa |
CCL2 | chemokine (C-C motif) ligand 2 |
CCNJL | cyclin J-like |
CD1E | CD1e molecule |
CD53 | CD53 molecule |
CDON | cell adhesion associated, oncogene regulated |
CFB | complement factor B |
CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
CLTC | clathrin, heavy chain (Hc) |
CNR2 | cannabinoid receptor 2 (macrophage) |
CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 |
CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
DAPK1 | death-associated protein kinase 1 |
DIO2 | deiodinase, iodothyronine, type II |
DOCK6 | dedicator of cytokinesis 6 |
EDA2R | ectodysplasin A2 receptor |
EHD2 | EH-domain containing 2 |
ELOVL5 | ELOVL fatty acid elongase 5 |
EMC3 | ER membrane protein complex subunit 3 |
FAM182B | family with sequence similarity 182, member B |
FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
GGT1 | gamma-glutamyltransferase 1 |
GLRA1 | glycine receptor, alpha 1 |
GLYAT | glycine-N-acyltransferase |
GP1BB | glycoprotein Ib (platelet), beta polypeptide |
GPR4 | G protein-coupled receptor 4 |
H2AFX | H2A histone family, member X |
HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
ICOSLG | inducible T-cell co-stimulator ligand |
IFI6 | interferon, alpha-inducible protein 6 |
IGLJ3 | immunoglobulin lambda joining 3 |
ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
ITIH4 | inter-alpha-trypsin inhibitor heavy chain family, member 4 |
KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
KIF13A | kinesin family member 13A |
KIF25 | kinesin family member 25 |
KLHDC8A | kelch domain containing 8A |
KRT15 | keratin 15, type I |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
MAPK8 | mitogen-activated protein kinase 8 |
MBD2 | methyl-CpG binding domain protein 2 |
MEF2D | myocyte enhancer factor 2D |
MSR1 | macrophage scavenger receptor 1 |
MT1G | metallothionein 1G |
MXD4 | MAX dimerization protein 4 |
MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
NKX2-5 | NK2 homeobox 5 |
NLGN4X | neuroligin 4, X-linked |
NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
PALM | paralemmin |
PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
PKP1 | plakophilin 1 |
PLCL2 | phospholipase C-like 2 |
PLXDC1 | plexin domain containing 1 |
PNPLA3 | patatin-like phospholipase domain containing 3 |
PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
RHO | rhodopsin |
RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
SLC43A3 | solute carrier family 43, member 3 |
SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
SSX3 | synovial sarcoma, X breakpoint 3 |
TBC1D29 | TBC1 domain family, member 29 |
TBRG4 | transforming growth factor beta regulator 4 |
TBX3 | T-box 3 |
TBXA2R | thromboxane A2 receptor |
THPO | thrombopoietin |
TMPRSS6 | transmembrane protease, serine 6 |
TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
TTC38 | tetratricopeptide repeat domain 38 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
UTS2 | urotensin 2 |
WSCD1 | WSC domain containing 1 |
ZC4H2 | zinc finger, C4H2 domain containing |
ZG16 | zymogen granule protein 16 |
Symbol | Name |
---|---|
A1CF | APOBEC1 complementation factor |
ACTL8 | actin-like 8 |
AMT | aminomethyltransferase |
ANP32A-IT1 | ANP32A intronic transcript 1 |
ATAD5 | ATPase family, AAA domain containing 5 |
ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
BAHCC1 | BAH domain and coiled-coil containing 1 |
BEX4 | brain expressed, X-linked 4 |
BHLHE41 | basic helix-loop-helix family, member e41 |
CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
CEP85 | centrosomal protein 85kDa |
CHKB | choline kinase beta |
CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
CNGB3 | cyclic nucleotide gated channel beta 3 |
CORO7 | coronin 7 |
CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
DBF4B | DBF4 zinc finger B |
DCAF13 | DDB1 and CUL4 associated factor 13 |
DGKE | diacylglycerol kinase, epsilon 64kDa |
DUSP8 | dual specificity phosphatase 8 |
EFNA3 | ephrin-A3 |
F2R | coagulation factor II (thrombin) receptor |
FBRS | fibrosin |
FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
FGL1 | fibrinogen-like 1 |
GAS2 | growth arrest-specific 2 |
GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
GUSBP3 | glucuronidase, beta pseudogene 3 |
HDAC5 | histone deacetylase 5 |
HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
HIST1H2AM | histone cluster 1, H2am |
IQCG | IQ motif containing G |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
KRT16 | keratin 16, type I |
LINC00115 | long intergenic non-protein coding RNA 115 |
LOC257152 | uncharacterized LOC257152 |
LYRM9 | LYR motif containing 9 |
MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
MGC12488 | |
MOSPD3 | motile sperm domain containing 3 |
MTCP1 | mature T-cell proliferation 1 |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NPIPB3 | nuclear pore complex interacting protein family, member B3 |
NT5E | 5'-nucleotidase, ecto (CD73) |
NXPH4 | neurexophilin 4 |
OLFML2A | olfactomedin-like 2A |
OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
OVGP1 | oviductal glycoprotein 1, 120kDa |
PCDHB8 | protocadherin beta 8 |
PICK1 | protein interacting with PRKCA 1 |
PITX2 | paired-like homeodomain 2 |
PMCH | pro-melanin-concentrating hormone |
PODNL1 | podocan-like 1 |
PORCN | porcupine homolog (Drosophila) |
PPT2 | palmitoyl-protein thioesterase 2 |
QPCT | glutaminyl-peptide cyclotransferase |
RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RAD54L2 | RAD54-like 2 (S. cerevisiae) |
RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
SAYSD1 | SAYSVFN motif domain containing 1 |
SCARA3 | scavenger receptor class A, member 3 |
SETD1B | SET domain containing 1B |
SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
SOWAHC | sosondowah ankyrin repeat domain family member C |
SPRYD7 | SPRY domain containing 7 |
SRD5A3 | steroid 5 alpha-reductase 3 |
STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
TBC1D19 | TBC1 domain family, member 19 |
TCHH | trichohyalin |
TESC | tescalcin |
THBS3 | thrombospondin 3 |
THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
THRAP3 | thyroid hormone receptor associated protein 3 |
TMEM183A | transmembrane protein 183A |
TMEM209 | transmembrane protein 209 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
TTBK2 | tau tubulin kinase 2 |
TWF2 | twinfilin actin binding protein 2 |
ZBTB25 | zinc finger and BTB domain containing 25 |
ZNF134 | zinc finger protein 134 |
ZNF37BP | zinc finger protein 37B, pseudogene |
ZNF428 | zinc finger protein 428 |
ZNF432 | zinc finger protein 432 |
ZNF571 | zinc finger protein 571 |
ZNF623 | zinc finger protein 623 |
ZNF778 | zinc finger protein 778 |
ZNRD1-AS1 | ZNRD1 antisense RNA 1 |