paromomycin-3017 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the paromomycin-3017 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ADAM7 ADAM metallopeptidase domain 7
ADIRF adipogenesis regulatory factor
AKAP6 A kinase (PRKA) anchor protein 6
APLP2 amyloid beta (A4) precursor-like protein 2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
B9D1 B9 protein domain 1
BAIAP2 BAI1-associated protein 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CHMP6 charged multivesicular body protein 6
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CPN2 carboxypeptidase N, polypeptide 2
CRAT carnitine O-acetyltransferase
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNAH3 dynein, axonemal, heavy chain 3
DOCK5 dedicator of cytokinesis 5
DUSP4 dual specificity phosphatase 4
DUSP7 dual specificity phosphatase 7
EGLN3 egl-9 family hypoxia-inducible factor 3
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FDPS farnesyl diphosphate synthase
GAL galanin/GMAP prepropeptide
GMPR guanosine monophosphate reductase
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H2BC histone cluster 1, H2bc
HIST1H3C histone cluster 1, H3c
HIST1H4E histone cluster 1, H4e
HIST2H2AA3 histone cluster 2, H2aa3
HOMER2 homer scaffolding protein 2
HPSE2 heparanase 2 (inactive)
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IL22 interleukin 22
INE1 inactivation escape 1 (non-protein coding)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNIP2 Kv channel interacting protein 2
KIF24 kinesin family member 24
LAMP1 lysosomal-associated membrane protein 1
LIMD2 LIM domain containing 2
LMOD1 leiomodin 1 (smooth muscle)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MCAM melanoma cell adhesion molecule
MCTP2 multiple C2 domains, transmembrane 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MUC4 mucin 4, cell surface associated
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NPR1 natriuretic peptide receptor 1
NPVF neuropeptide VF precursor
NPY4R neuropeptide Y receptor Y4
NRF1 nuclear respiratory factor 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ONECUT2 one cut homeobox 2
OPCML opioid binding protein/cell adhesion molecule-like
PALLD palladin, cytoskeletal associated protein
PARK2 parkin RBR E3 ubiquitin protein ligase
PCDHGA8 protocadherin gamma subfamily A, 8
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDIA2 protein disulfide isomerase family A, member 2
POU1F1 POU class 1 homeobox 1
PRAMEF11 PRAME family member 11
PROS1 protein S (alpha)
PRSS22 protease, serine, 22
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PVR poliovirus receptor
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RARB retinoic acid receptor, beta
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRAD Ras-related associated with diabetes
SCIN scinderin
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH3BP1 SH3-domain binding protein 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A8 solute carrier family 12, member 8
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC39A9 solute carrier family 39, member 9
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SNPH syntaphilin
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRP72 signal recognition particle 72kDa
SSBP2 single-stranded DNA binding protein 2
SSTR4 somatostatin receptor 4
STAP1 signal transducing adaptor family member 1
SVIL supervillin
TEAD3 TEA domain family member 3
TLN2 talin 2
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TP63 tumor protein p63
VCX2 variable charge, X-linked 2
WNT16 wingless-type MMTV integration site family, member 16
WWTR1 WW domain containing transcription regulator 1
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADGRD2 adhesion G protein-coupled receptor D2
ANXA2P3 annexin A2 pseudogene 3
ATAT1 alpha tubulin acetyltransferase 1
BAG4 BCL2-associated athanogene 4
BCAR3 breast cancer anti-estrogen resistance 3
C11ORF63 chromosome 11 open reading frame 63
C11ORF68 chromosome 11 open reading frame 68
C1ORF21 chromosome 1 open reading frame 21
C3ORF14 chromosome 3 open reading frame 14
C3ORF18 chromosome 3 open reading frame 18
C8ORF44 chromosome 8 open reading frame 44
CCDC85C coiled-coil domain containing 85C
CD3D CD3d molecule, delta (CD3-TCR complex)
CD70 CD70 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDHR2 cadherin-related family member 2
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CFAP45 cilia and flagella associated protein 45
CFAP69 cilia and flagella associated protein 69
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CNN1 calponin 1, basic, smooth muscle
CNR2 cannabinoid receptor 2 (macrophage)
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DGAT1 diacylglycerol O-acyltransferase 1
EHD3 EH-domain containing 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM106A family with sequence similarity 106, member A
FANCC Fanconi anemia, complementation group C
FBRS fibrosin
FBXL7 F-box and leucine-rich repeat protein 7
FCHO1 FCH domain only 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAREM GRB2 associated, regulator of MAPK1
HCG4 HLA complex group 4 (non-protein coding)
HIST1H2AJ histone cluster 1, H2aj
HOXA2 homeobox A2
HOXA6 homeobox A6
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA14 interferon, alpha 14
IFT54 intraflagellar transport 54
IL37 interleukin 37
IL4R interleukin 4 receptor
JPH3 junctophilin 3
KIAA1024 KIAA1024
KIAA1107 KIAA1107
KIF13B kinesin family member 13B
KRT12 keratin 12, type I
KRT20 keratin 20, type I
KRT81 keratin 81, type II
LEFTY2 left-right determination factor 2
LPPR1 lipid phosphate phosphatase-related protein type 1
LTBP2 latent transforming growth factor beta binding protein 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUC6 mucin 6, oligomeric mucus/gel-forming
MYH4 myosin, heavy chain 4, skeletal muscle
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NINJ2 ninjurin 2
NLGN1 neuroligin 1
NMUR1 neuromedin U receptor 1
NPFFR1 neuropeptide FF receptor 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHACTR4 phosphatase and actin regulator 4
PKD2L2 polycystic kidney disease 2-like 2
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RAB33A RAB33A, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SFRP5 secreted frizzled-related protein 5
SKA1 spindle and kinetochore associated complex subunit 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLITRK5 SLIT and NTRK-like family, member 5
SNAI1 snail family zinc finger 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STX1A syntaxin 1A (brain)
TEX15 testis expressed 15
THEM6 thioesterase superfamily member 6
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM140 transmembrane protein 140
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UNC13A unc-13 homolog A (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFB vascular endothelial growth factor B
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPREB1 pre-B lymphocyte 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YPEL1 yippee-like 1 (Drosophila)
ZNF280A zinc finger protein 280A