paromomycin-3356 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the paromomycin-3356 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD26 ankyrin repeat domain 26
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARID5A AT rich interactive domain 5A (MRF1-like)
ASIC1 acid sensing (proton gated) ion channel 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CCDC85B coiled-coil domain containing 85B
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CIB2 calcium and integrin binding family member 2
CLIC2 chloride intracellular channel 2
CNR2 cannabinoid receptor 2 (macrophage)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSNK1G1 casein kinase 1, gamma 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNS cystinosin, lysosomal cystine transporter
CTSZ cathepsin Z
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DEAF1 DEAF1 transcription factor
DMXL2 Dmx-like 2
DUSP1 dual specificity phosphatase 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERCC2 excision repair cross-complementation group 2
EZR ezrin
FCMR Fc fragment of IgM receptor
FGF5 fibroblast growth factor 5
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK3P glycerol kinase 3 pseudogene
GRM7 glutamate receptor, metabotropic 7
HAND1 heart and neural crest derivatives expressed 1
HIF3A hypoxia inducible factor 3, alpha subunit
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL22 kelch-like family member 22
KRIT1 KRIT1, ankyrin repeat containing
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LINC01587 long intergenic non-protein coding RNA 1587
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGEA5 melanoma antigen family A5
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAPT microtubule-associated protein tau
MC5R melanocortin 5 receptor
MR1 major histocompatibility complex, class I-related
MRPL41 mitochondrial ribosomal protein L41
MST1L macrophage stimulating 1-like
MYOF myoferlin
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPFF neuropeptide FF-amide peptide precursor
NR2F1 nuclear receptor subfamily 2, group F, member 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PARD6B par-6 family cell polarity regulator beta
PER3 period circadian clock 3
PKNOX1 PBX/knotted 1 homeobox 1
PLXNB1 plexin B1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRB1 proline-rich protein BstNI subfamily 1
PRKCE protein kinase C, epsilon
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAI2 retinoic acid induced 2
RASAL2 RAS protein activator like 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS2 regulator of G-protein signaling 2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAFB2 scaffold attachment factor B2
SAG S-antigen; retina and pineal gland (arrestin)
SDC2 syndecan 2
SECTM1 secreted and transmembrane 1
SERHL2 serine hydrolase-like 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPRR1B small proline-rich protein 1B
SPRY4 sprouty homolog 4 (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
SRSF7 serine/arginine-rich splicing factor 7
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT2 synaptotagmin II
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TTLL4 tubulin tyrosine ligase-like family member 4
UBQLN4 ubiquilin 4
VPS13B vacuolar protein sorting 13 homolog B (yeast)
XYLT1 xylosyltransferase I
YY2 YY2 transcription factor
ZC3H7B zinc finger CCCH-type containing 7B
ZNF175 zinc finger protein 175
ZNF280A zinc finger protein 280A
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACVR2B activin A receptor, type IIB
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHCC1 BAH domain and coiled-coil containing 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP4 bone morphogenetic protein 4
C10ORF95 chromosome 10 open reading frame 95
C22ORF46 chromosome 22 open reading frame 46
C5AR2 complement component 5a receptor 2
CCDC25 coiled-coil domain containing 25
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPO centromere protein O
CHRM3 cholinergic receptor, muscarinic 3
CLCN6 chloride channel, voltage-sensitive 6
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNTN1 contactin 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CUL9 cullin 9
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCAF4 DDB1 and CUL4 associated factor 4
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM1 dynamin 1
DYSF dysferlin
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
EXOC6B exocyst complex component 6B
F2R coagulation factor II (thrombin) receptor
FAM155B family with sequence similarity 155, member B
FGL1 fibrinogen-like 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXI1 forkhead box I1
FOXN2 forkhead box N2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR143 G protein-coupled receptor 143
HCFC2 host cell factor C2
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC8 homeobox C8
IQCG IQ motif containing G
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLF7 Kruppel-like factor 7 (ubiquitous)
LIG4 ligase IV, DNA, ATP-dependent
LMCD1 LIM and cysteine-rich domains 1
LPXN leupaxin
LRP2 low density lipoprotein receptor-related protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MEFV Mediterranean fever
MTA2 metastasis associated 1 family, member 2
MYL5 myosin, light chain 5, regulatory
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PDE8B phosphodiesterase 8B
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POPDC3 popeye domain containing 3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTCD2 pentatricopeptide repeat domain 2
RECQL4 RecQ protein-like 4
RHOBTB2 Rho-related BTB domain containing 2
RPGR retinitis pigmentosa GTPase regulator
RPGRIP1L RPGRIP1-like
SKI SKI proto-oncogene
SMIM14 small integral membrane protein 14
ST5 suppression of tumorigenicity 5
TBC1D2 TBC1 domain family, member 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX19 T-box 19
TESC tescalcin
TFF2 trefoil factor 2
THRB thyroid hormone receptor, beta
TMC5 transmembrane channel-like 5
TMEM212 transmembrane protein 212
TONSL tonsoku-like, DNA repair protein
TRAIP TRAF interacting protein
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
WDR25 WD repeat domain 25
XDH xanthine dehydrogenase
ZBTB22 zinc finger and BTB domain containing 22
ZNF37BP zinc finger protein 37B, pseudogene
ZNF446 zinc finger protein 446