| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the paromomycin-4420 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADRA1D | adrenoceptor alpha 1D |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| CCDC87 | coiled-coil domain containing 87 |
| CD6 | CD6 molecule |
| CEP112 | centrosomal protein 112kDa |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLEC7A | C-type lectin domain family 7, member A |
| CLSTN3 | calsyntenin 3 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL1A1 | collagen, type I, alpha 1 |
| COL8A2 | collagen, type VIII, alpha 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CTSZ | cathepsin Z |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYTH4 | cytohesin 4 |
| DAPK2 | death-associated protein kinase 2 |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DOPEY2 | dopey family member 2 |
| E2F2 | E2F transcription factor 2 |
| FAM163A | family with sequence similarity 163, member A |
| FGL2 | fibrinogen-like 2 |
| FST | follistatin |
| GGT1 | gamma-glutamyltransferase 1 |
| GM2A | GM2 ganglioside activator |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR85 | G protein-coupled receptor 85 |
| GUCY2D | guanylate cyclase 2D, membrane (retina-specific) |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HCRT | hypocretin (orexin) neuropeptide precursor |
| HDLBP | high density lipoprotein binding protein |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HOXA6 | homeobox A6 |
| IL36G | interleukin 36, gamma |
| IVL | involucrin |
| KIAA1109 | KIAA1109 |
| KLHDC8A | kelch domain containing 8A |
| LARGE | like-glycosyltransferase |
| LEFTY1 | left-right determination factor 1 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LYZL6 | lysozyme-like 6 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCAM | melanoma cell adhesion molecule |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYH8 | myosin, heavy chain 8, skeletal muscle, perinatal |
| MYO9B | myosin IXB |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NEFM | neurofilament, medium polypeptide |
| NTF3 | neurotrophin 3 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PLXNB1 | plexin B1 |
| POU2F2 | POU class 2 homeobox 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RARA | retinoic acid receptor, alpha |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIF1 | replication timing regulatory factor 1 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RUNX1 | runt-related transcription factor 1 |
| RUNX3 | runt-related transcription factor 3 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SELE | selectin E |
| SH3BP1 | SH3-domain binding protein 1 |
| SHOX2 | short stature homeobox 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPTB | spectrin, beta, erythrocytic |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| THY1 | Thy-1 cell surface antigen |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TP63 | tumor protein p63 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| VN1R1 | vomeronasal 1 receptor 1 |
| VNN1 | vanin 1 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AFAP1 | actin filament associated protein 1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARMC4 | armadillo repeat containing 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAX | BCL2-associated X protein |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CTSF | cathepsin F |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DIXDC1 | DIX domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| ERCC6 | excision repair cross-complementation group 6 |
| ETV6 | ets variant 6 |
| FAM204A | family with sequence similarity 204, member A |
| FBXO31 | F-box protein 31 |
| FER | fer (fps/fes related) tyrosine kinase |
| FOXJ2 | forkhead box J2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GAMT | guanidinoacetate N-methyltransferase |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIRA | histone cell cycle regulator |
| HIST1H2BC | histone cluster 1, H2bc |
| HOXB2 | homeobox B2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT22 | intraflagellar transport 22 |
| IFT54 | intraflagellar transport 54 |
| IPO8 | importin 8 |
| IRF9 | interferon regulatory factor 9 |
| KIAA0895 | KIAA0895 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT24 | keratin 24, type I |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMNB1 | lamin B1 |
| LOC157562 | uncharacterized LOC157562 |
| MBTD1 | mbt domain containing 1 |
| MEGF6 | multiple EGF-like-domains 6 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| NBEA | neurobeachin |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NLRX1 | NLR family member X1 |
| NME5 | NME/NM23 family member 5 |
| NRSN2 | neurensin 2 |
| OLFML2A | olfactomedin-like 2A |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PITX2 | paired-like homeodomain 2 |
| PLCD1 | phospholipase C, delta 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKCE | protein kinase C, epsilon |
| PROS1 | protein S (alpha) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A2 | S100 calcium binding protein A2 |
| S100A4 | S100 calcium binding protein A4 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SKI | SKI proto-oncogene |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STRA6 | stimulated by retinoic acid 6 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM120B | transmembrane protein 120B |
| TPSG1 | tryptase gamma 1 |
| TRIM36 | tripartite motif containing 36 |
| TSGA10 | testis specific, 10 |
| TTC17 | tetratricopeptide repeat domain 17 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VLDLR | very low density lipoprotein receptor |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| ZNF286A | zinc finger protein 286A |
| ZNF623 | zinc finger protein 623 |
| ZNF675 | zinc finger protein 675 |
