| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the paroxetine-3904 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM2 | adrenomedullin 2 |
| AIRE | autoimmune regulator |
| ALPK1 | alpha-kinase 1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BGN | biglycan |
| BMP5 | bone morphogenetic protein 5 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC57 | coiled-coil domain containing 57 |
| CD53 | CD53 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CRAT | carnitine O-acetyltransferase |
| CREBBP | CREB binding protein |
| CRYM | crystallin, mu |
| CTF1 | cardiotrophin 1 |
| CTSE | cathepsin E |
| CXORF21 | chromosome X open reading frame 21 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DRD2 | dopamine receptor D2 |
| EDNRB | endothelin receptor type B |
| EGR1 | early growth response 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EXOSC1 | exosome component 1 |
| EZR | ezrin |
| FAM182B | family with sequence similarity 182, member B |
| FAM63B | family with sequence similarity 63, member B |
| FCMR | Fc fragment of IgM receptor |
| FGF6 | fibroblast growth factor 6 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FRMD8 | FERM domain containing 8 |
| GGT1 | gamma-glutamyltransferase 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPR25 | G protein-coupled receptor 25 |
| GPSM3 | G-protein signaling modulator 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HOXB9 | homeobox B9 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| ICOS | inducible T-cell co-stimulator |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNA10 | interferon, alpha 10 |
| IL6 | interleukin 6 |
| IL6ST | interleukin 6 signal transducer |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| IRF5 | interferon regulatory factor 5 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| IVL | involucrin |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KRT8 | keratin 8, type II |
| LHB | luteinizing hormone beta polypeptide |
| LOXL3 | lysyl oxidase-like 3 |
| MAGEA5 | melanoma antigen family A5 |
| MMP11 | matrix metallopeptidase 11 |
| MST1 | macrophage stimulating 1 |
| MYO1A | myosin IA |
| NABP1 | nucleic acid binding protein 1 |
| NCOA2 | nuclear receptor coactivator 2 |
| NEFL | neurofilament, light polypeptide |
| NNAT | neuronatin |
| NOTCH4 | notch 4 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NUP214 | nucleoporin 214kDa |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PDE9A | phosphodiesterase 9A |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIGR | polymeric immunoglobulin receptor |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAUR | plasminogen activator, urokinase receptor |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PQLC2 | PQ loop repeat containing 2 |
| PRX | periaxin |
| RORC | RAR-related orphan receptor C |
| RUSC2 | RUN and SH3 domain containing 2 |
| SASH3 | SAM and SH3 domain containing 3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SIRT5 | sirtuin 5 |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| SPEG | SPEG complex locus |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TBXA2R | thromboxane A2 receptor |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX15 | testis expressed 15 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WAPAL | wings apart-like homolog (Drosophila) |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADCY6 | adenylate cyclase 6 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AMT | aminomethyltransferase |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C3 | complement component 3 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC64 | coiled-coil domain containing 64 |
| CCNK | cyclin K |
| CHKB | choline kinase beta |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORO7 | coronin 7 |
| CRLF1 | cytokine receptor-like factor 1 |
| CSF1R | colony stimulating factor 1 receptor |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| EMP3 | epithelial membrane protein 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| ETNK2 | ethanolamine kinase 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM120C | family with sequence similarity 120C |
| FMOD | fibromodulin |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPR176 | G protein-coupled receptor 176 |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H3E | histone cluster 1, H3e |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC10 | homeobox C10 |
| HOXC4 | homeobox C4 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF6 | interferon regulatory factor 6 |
| ITM2C | integral membrane protein 2C |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLK8 | kallikrein-related peptidase 8 |
| KRT13 | keratin 13, type I |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPTX1 | neuronal pentraxin I |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHB3 | protocadherin beta 3 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLA2G3 | phospholipase A2, group III |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PODNL1 | podocan-like 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRAMEF11 | PRAME family member 11 |
| PRSS53 | protease, serine, 53 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB3D | RAB3D, member RAS oncogene family |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF170 | ring finger protein 170 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPGRIP1L | RPGRIP1-like |
| SCARA3 | scavenger receptor class A, member 3 |
| SIRT4 | sirtuin 4 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRPX | sushi-repeat containing protein, X-linked |
| STAB2 | stabilin 2 |
| SYNC | syncoilin, intermediate filament protein |
| TBC1D2 | TBC1 domain family, member 2 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TH | tyrosine hydroxylase |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP6NL | USP6 N-terminal like |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF34 | zinc finger protein 34 |
| ZNF492 | zinc finger protein 492 |
| ZNF623 | zinc finger protein 623 |
