| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the paroxetine-4378 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK4 | aarF domain containing kinase 4 |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| APOC1 | apolipoprotein C-I |
| ART1 | ADP-ribosyltransferase 1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CADM4 | cell adhesion molecule 4 |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC7 | coiled-coil domain containing 7 |
| CD47 | CD47 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CEMP1 | cementum protein 1 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLCA1 | chloride channel accessory 1 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| DMWD | dystrophia myotonica, WD repeat containing |
| DOK4 | docking protein 4 |
| DTNA | dystrobrevin, alpha |
| EMID1 | EMI domain containing 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FAM182B | family with sequence similarity 182, member B |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAS7 | growth arrest-specific 7 |
| GK | glycerol kinase |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GUCA1A | guanylate cyclase activator 1A (retina) |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| HYAL3 | hyaluronoglucosaminidase 3 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL36R | interleukin 36 receptor |
| KCNC2 | potassium channel, voltage gated Shaw related subfamily C, member 2 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA0754 | KIAA0754 |
| KRT32 | keratin 32, type I |
| LAMC3 | laminin, gamma 3 |
| LAT2 | linker for activation of T cells family, member 2 |
| LDHC | lactate dehydrogenase C |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MST1 | macrophage stimulating 1 |
| MTMR3 | myotubularin related protein 3 |
| MXD4 | MAX dimerization protein 4 |
| NEUROD6 | neuronal differentiation 6 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPTX2 | neuronal pentraxin II |
| OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| SAPCD1 | suppressor APC domain containing 1 |
| SFTPC | surfactant protein C |
| SHOX2 | short stature homeobox 2 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SYK | spleen tyrosine kinase |
| TARP | TCR gamma alternate reading frame protein |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNPO2 | transportin 2 |
| TRD | T cell receptor delta locus |
| TSC2 | tuberous sclerosis 2 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| XIST | X inactive specific transcript (non-protein coding) |
| YOD1 | YOD1 deubiquitinase |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF682 | zinc finger protein 682 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C3 | complement component 3 |
| C5AR2 | complement component 5a receptor 2 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CBX2 | chromobox homolog 2 |
| CBX8 | chromobox homolog 8 |
| CCDC69 | coiled-coil domain containing 69 |
| CCNO | cyclin O |
| CD70 | CD70 molecule |
| CEL | carboxyl ester lipase |
| CFHR4 | complement factor H-related 4 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CNTFR | ciliary neurotrophic factor receptor |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| DUSP13 | dual specificity phosphatase 13 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| F9 | coagulation factor IX |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GMPR | guanosine monophosphate reductase |
| GRAMD1C | GRAM domain containing 1C |
| GSTP1 | glutathione S-transferase pi 1 |
| HDAC11 | histone deacetylase 11 |
| HDAC7 | histone deacetylase 7 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2BO | histone cluster 1, H2bo |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFNA14 | interferon, alpha 14 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ISL1 | ISL LIM homeobox 1 |
| ITM2C | integral membrane protein 2C |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KIAA1324 | KIAA1324 |
| KIAA1462 | KIAA1462 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LYRM9 | LYR motif containing 9 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MGC2889 | uncharacterized protein MGC2889 |
| NAG18 | NAG18 mRNA |
| NEUROD1 | neuronal differentiation 1 |
| OLFML2A | olfactomedin-like 2A |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSMR | oncostatin M receptor |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIPOX | pipecolic acid oxidase |
| PLA2G3 | phospholipase A2, group III |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POU3F2 | POU class 3 homeobox 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PROL1 | proline rich, lacrimal 1 |
| PTX3 | pentraxin 3, long |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPA4 | replication protein A4, 30kDa |
| SCARA3 | scavenger receptor class A, member 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STEAP4 | STEAP family member 4 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCTN2 | tectonic family member 2 |
| TEX14 | testis expressed 14 |
| TEX40 | testis expressed 40 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRIM68 | tripartite motif containing 68 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF639 | zinc finger protein 639 |