| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the paroxetine-4556 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| C4BPA | complement component 4 binding protein, alpha |
| C5AR1 | complement component 5a receptor 1 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCDC64 | coiled-coil domain containing 64 |
| CCL24 | chemokine (C-C motif) ligand 24 |
| CD7 | CD7 molecule |
| CD80 | CD80 molecule |
| CNN1 | calponin 1, basic, smooth muscle |
| COMMD4 | COMM domain containing 4 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYTH4 | cytohesin 4 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DRD2 | dopamine receptor D2 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| FGFR2 | fibroblast growth factor receptor 2 |
| FH | fumarate hydratase |
| FYB | FYN binding protein |
| GAS7 | growth arrest-specific 7 |
| GHRHR | growth hormone releasing hormone receptor |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPR22 | G protein-coupled receptor 22 |
| HIST1H2BM | histone cluster 1, H2bm |
| HOXD13 | homeobox D13 |
| HOXD3 | homeobox D3 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| HYAL4 | hyaluronoglucosaminidase 4 |
| IFNA14 | interferon, alpha 14 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2 | interleukin 2 |
| ING4 | inhibitor of growth family, member 4 |
| KIF5C | kinesin family member 5C |
| KLK2 | kallikrein-related peptidase 2 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT14 | keratin 14, type I |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LILRP2 | leukocyte immunoglobulin-like receptor pseudogene 2 |
| METTL7A | methyltransferase like 7A |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| MYOZ3 | myozenin 3 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NEUROD1 | neuronal differentiation 1 |
| NF1 | neurofibromin 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| NTF3 | neurotrophin 3 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OCM2 | oncomodulin 2 |
| OLFM1 | olfactomedin 1 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PASK | PAS domain containing serine/threonine kinase |
| PAX8 | paired box 8 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDHB12 | protocadherin beta 12 |
| PDCD2 | programmed cell death 2 |
| PDE10A | phosphodiesterase 10A |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PENK | proenkephalin |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PLA2G5 | phospholipase A2, group V |
| PLK4 | polo-like kinase 4 |
| PLP1 | proteolipid protein 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PYY | peptide YY |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RFXAP | regulatory factor X-associated protein |
| S100A5 | S100 calcium binding protein A5 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SULF1 | sulfatase 1 |
| TFR2 | transferrin receptor 2 |
| TLR4 | toll-like receptor 4 |
| TMEM212 | transmembrane protein 212 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| WDR59 | WD repeat domain 59 |
| ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF518A | zinc finger protein 518A |
| ZNF749 | zinc finger protein 749 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AEN | apoptosis enhancing nuclease |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CDK9 | cyclin-dependent kinase 9 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEP70 | centrosomal protein 70kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUEDC1 | CUE domain containing 1 |
| DBR1 | debranching RNA lariats 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOLPP1 | dolichyldiphosphatase 1 |
| EFNA3 | ephrin-A3 |
| EGR2 | early growth response 2 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERF | Ets2 repressor factor |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM53B | family with sequence similarity 53, member B |
| FANCC | Fanconi anemia, complementation group C |
| FOXC1 | forkhead box C1 |
| FOXK2 | forkhead box K2 |
| FPGS | folylpolyglutamate synthase |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GMIP | GEM interacting protein |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HELZ | helicase with zinc finger |
| HIRA | histone cell cycle regulator |
| HMOX1 | heme oxygenase 1 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFI44L | interferon-induced protein 44-like |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IL17RA | interleukin 17 receptor A |
| IL4R | interleukin 4 receptor |
| JMJD4 | jumonji domain containing 4 |
| KIAA0319L | KIAA0319-like |
| KIAA1462 | KIAA1462 |
| KPTN | kaptin (actin binding protein) |
| LBR | lamin B receptor |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MST1R | macrophage stimulating 1 receptor |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NRTN | neurturin |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PROSER1 | proline and serine rich 1 |
| PSKH1 | protein serine kinase H1 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RNF123 | ring finger protein 123 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SECISBP2 | SECIS binding protein 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMAP1 | small ArfGAP 1 |
| SNX16 | sorting nexin 16 |
| STK16 | serine/threonine kinase 16 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TCTN1 | tectonic family member 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM53 | transmembrane protein 53 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOR4A | torsin family 4, member A |
| TRIM21 | tripartite motif containing 21 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF264 | zinc finger protein 264 |
| ZNF276 | zinc finger protein 276 |
| ZNF358 | zinc finger protein 358 |
