| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the parthenolide-2885 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AEN | apoptosis enhancing nuclease |
| AMOTL2 | angiomotin like 2 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BANP | BTG3 associated nuclear protein |
| BTG2 | BTG family, member 2 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CBR3 | carbonyl reductase 3 |
| CD82 | CD82 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CREM | cAMP responsive element modulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTGF | connective tissue growth factor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAPK3 | death-associated protein kinase 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP5 | dual specificity phosphatase 5 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EGR1 | early growth response 1 |
| EPHA2 | EPH receptor A2 |
| ERP44 | endoplasmic reticulum protein 44 |
| FAM53C | family with sequence similarity 53, member C |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H4H | histone cluster 1, H4h |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER5 | immediate early response 5 |
| IL6R | interleukin 6 receptor |
| JMJD6 | jumonji domain containing 6 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KIAA0368 | KIAA0368 |
| KLF2 | Kruppel-like factor 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL24 | kelch-like family member 24 |
| KLHL25 | kelch-like family member 25 |
| LIF | leukemia inhibitory factor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MEF2D | myocyte enhancer factor 2D |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MIR22HG | MIR22 host gene |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PER1 | period circadian clock 1 |
| PGF | placental growth factor |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| RGS2 | regulator of G-protein signaling 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SESN1 | sestrin 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TES | testin LIM domain protein |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TUFT1 | tuftelin 1 |
| TXNRD1 | thioredoxin reductase 1 |
| ULBP1 | UL16 binding protein 1 |
| VAMP4 | vesicle-associated membrane protein 4 |
| VEGFA | vascular endothelial growth factor A |
| ZFP36 | ZFP36 ring finger protein |
| ZNF10 | zinc finger protein 10 |
| ZNF143 | zinc finger protein 143 |
| ZNF230 | zinc finger protein 230 |
| ZNF329 | zinc finger protein 329 |
| ZNF419 | zinc finger protein 419 |
| ZNF473 | zinc finger protein 473 |
| ZNF606 | zinc finger protein 606 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| B3GNT1 | |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| CCNE2 | cyclin E2 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| E2F8 | E2F transcription factor 8 |
| EGR3 | early growth response 3 |
| EPHA4 | EPH receptor A4 |
| EPN3 | epsin 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EVPL | envoplakin |
| F8 | coagulation factor VIII, procoagulant component |
| FAM172A | family with sequence similarity 172, member A |
| FAM46A | family with sequence similarity 46, member A |
| FBXO5 | F-box protein 5 |
| FJX1 | four jointed box 1 (Drosophila) |
| FKBPL | FK506 binding protein like |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FZD2 | frizzled class receptor 2 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GLCE | glucuronic acid epimerase |
| GPR137B | G protein-coupled receptor 137B |
| GPR19 | G protein-coupled receptor 19 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H4C | histone cluster 1, H4c |
| HJURP | Holliday junction recognition protein |
| HOXC6 | homeobox C6 |
| HTRA1 | HtrA serine peptidase 1 |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IRF2 | interferon regulatory factor 2 |
| IRS1 | insulin receptor substrate 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KITLG | KIT ligand |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LOC100287590 | uncharacterized LOC100287590 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MEIS1 | Meis homeobox 1 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MSMB | microseminoprotein, beta- |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NAV2 | neuron navigator 2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NKRF | NFKB repressing factor |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5DC2 | 5'-nucleotidase domain containing 2 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLK2 | polo-like kinase 2 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PROS1 | protein S (alpha) |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RGS16 | regulator of G-protein signaling 16 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SETD6 | SET domain containing 6 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SYBU | syntabulin (syntaxin-interacting) |
| TMEM168 | transmembrane protein 168 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRIM32 | tripartite motif containing 32 |
| TRIM45 | tripartite motif containing 45 |
| TRIM52 | tripartite motif containing 52 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSPYL5 | TSPY-like 5 |
| TUBA3D | tubulin, alpha 3d |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| TXNIP | thioredoxin interacting protein |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZIC1 | Zic family member 1 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF492 | zinc finger protein 492 |
| ZNF532 | zinc finger protein 532 |
