| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the parthenolide-5105 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADM | adrenomedullin |
| AHI1 | Abelson helper integration site 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARG2 | arginase 2 |
| ATF3 | activating transcription factor 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BRD2 | bromodomain containing 2 |
| BTG2 | BTG family, member 2 |
| CBX4 | chromobox homolog 4 |
| CCNE1 | cyclin E1 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| COL8A1 | collagen, type VIII, alpha 1 |
| CREM | cAMP responsive element modulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| EFNB2 | ephrin-B2 |
| EGR1 | early growth response 1 |
| FAM46A | family with sequence similarity 46, member A |
| FAM46C | family with sequence similarity 46, member C |
| FAM53C | family with sequence similarity 53, member C |
| FGF18 | fibroblast growth factor 18 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| FZD7 | frizzled class receptor 7 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFI1 | growth factor independent 1 transcription repressor |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GLS | glutaminase |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IRS2 | insulin receptor substrate 2 |
| JMJD6 | jumonji domain containing 6 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL21 | kelch-like family member 21 |
| KLHL24 | kelch-like family member 24 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC157562 | uncharacterized LOC157562 |
| LRP2BP | LRP2 binding protein |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MIR22HG | MIR22 host gene |
| MTRF1 | mitochondrial translational release factor 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAV3 | neuron navigator 3 |
| NXF1 | nuclear RNA export factor 1 |
| OSER1 | oxidative stress responsive serine-rich 1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PLEK | pleckstrin |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAI2 | retinoic acid induced 2 |
| RAPSN | receptor-associated protein of the synapse |
| RASAL2 | RAS protein activator like 2 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGCC | regulator of cell cycle |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RNF103 | ring finger protein 103 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SETD4 | SET domain containing 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMEM2 | transmembrane protein 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM26 | tripartite motif containing 26 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF235 | zinc finger protein 235 |
| Symbol | Name |
|---|---|
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BCOR | BCL6 corepressor |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CCNJ | cyclin J |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DBR1 | debranching RNA lariats 1 |
| DUSP4 | dual specificity phosphatase 4 |
| E2F8 | E2F transcription factor 8 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM169A | family with sequence similarity 169, member A |
| FJX1 | four jointed box 1 (Drosophila) |
| GBX2 | gastrulation brain homeobox 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLCE | glucuronic acid epimerase |
| GPR137B | G protein-coupled receptor 137B |
| GRAMD1B | GRAM domain containing 1B |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| GSPT2 | G1 to S phase transition 2 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HELLS | helicase, lymphoid-specific |
| HIST1H1D | histone cluster 1, H1d |
| HMGA2 | high mobility group AT-hook 2 |
| HOXA10 | homeobox A10 |
| HOXA5 | homeobox A5 |
| HOXA9 | homeobox A9 |
| HOXC6 | homeobox C6 |
| IER3 | immediate early response 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IMPACT | impact RWD domain protein |
| IRS1 | insulin receptor substrate 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LIF | leukemia inhibitory factor |
| LMNB1 | lamin B1 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAGEF1 | melanoma antigen family F1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEIS1 | Meis homeobox 1 |
| MGC12488 | |
| MKL2 | MKL/myocardin-like 2 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| NAP1L3 | nucleosome assembly protein 1-like 3 |
| NDP | Norrie disease (pseudoglioma) |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NHLRC2 | NHL repeat containing 2 |
| NKRF | NFKB repressing factor |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PALMD | palmdelphin |
| PAX6 | paired box 6 |
| PCTP | phosphatidylcholine transfer protein |
| PGAP1 | post-GPI attachment to proteins 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PROS1 | protein S (alpha) |
| PRR3 | proline rich 3 |
| PSKH1 | protein serine kinase H1 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 |
| RAB20 | RAB20, member RAS oncogene family |
| RIN2 | Ras and Rab interactor 2 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| SALL2 | spalt-like transcription factor 2 |
| SCAF8 | SR-related CTD-associated factor 8 |
| SETD6 | SET domain containing 6 |
| SHROOM2 | shroom family member 2 |
| SIX1 | SIX homeobox 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| ST5 | suppression of tumorigenicity 5 |
| STK16 | serine/threonine kinase 16 |
| TGFB3 | transforming growth factor, beta 3 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM168 | transmembrane protein 168 |
| TMEM177 | transmembrane protein 177 |
| TRIM25 | tripartite motif containing 25 |
| TRIM32 | tripartite motif containing 32 |
| ZFHX4 | zinc finger homeobox 4 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF215 | zinc finger protein 215 |
| ZNF273 | zinc finger protein 273 |
| ZNF33B | zinc finger protein 33B |
| ZNF443 | zinc finger protein 443 |
| ZNF552 | zinc finger protein 552 |
| ZNF652 | zinc finger protein 652 |
| ZNF85 | zinc finger protein 85 |
