| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the parthenolide-5530 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AEN | apoptosis enhancing nuclease |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BAIAP2 | BAI1-associated protein 2 |
| BANP | BTG3 associated nuclear protein |
| BRD2 | bromodomain containing 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C5AR1 | complement component 5a receptor 1 |
| CBR3 | carbonyl reductase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CREM | cAMP responsive element modulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DAPK3 | death-associated protein kinase 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EMC3 | ER membrane protein complex subunit 3 |
| EPHA2 | EPH receptor A2 |
| EXOC6B | exocyst complex component 6B |
| FAM53C | family with sequence similarity 53, member C |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| FSCN1 | fascin actin-bundling protein 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HOXB3 | homeobox B3 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL6R | interleukin 6 receptor |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JMJD6 | jumonji domain containing 6 |
| JRK | Jrk homolog (mouse) |
| KDM3A | lysine (K)-specific demethylase 3A |
| KLF2 | Kruppel-like factor 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LYST | lysosomal trafficking regulator |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MICB | MHC class I polypeptide-related sequence B |
| MIR22HG | MIR22 host gene |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MTA2 | metastasis associated 1 family, member 2 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RIT1 | Ras-like without CAAX 1 |
| RRBP1 | ribosome binding protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERTAD2 | SERTA domain containing 2 |
| SESN1 | sestrin 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOCS1 | suppressor of cytokine signaling 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TBL2 | transducin (beta)-like 2 |
| TES | testin LIM domain protein |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNIK | TRAF2 and NCK interacting kinase |
| TOR1AIP1 | torsin A interacting protein 1 |
| TULP3 | tubby like protein 3 |
| TXNRD1 | thioredoxin reductase 1 |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| UNC119 | unc-119 homolog (C. elegans) |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZFP36 | ZFP36 ring finger protein |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF10 | zinc finger protein 10 |
| ZNF230 | zinc finger protein 230 |
| ZNF335 | zinc finger protein 335 |
| ZNF45 | zinc finger protein 45 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACOT8 | acyl-CoA thioesterase 8 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| B3GNT1 | |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| CBX7 | chromobox homolog 7 |
| CCDC170 | coiled-coil domain containing 170 |
| CDC7 | cell division cycle 7 |
| CFD | complement factor D (adipsin) |
| CHKB | choline kinase beta |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| E2F8 | E2F transcription factor 8 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPN3 | epsin 3 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| FAM111A | family with sequence similarity 111, member A |
| FBXO5 | F-box protein 5 |
| FJX1 | four jointed box 1 (Drosophila) |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FZD2 | frizzled class receptor 2 |
| FZD4 | frizzled class receptor 4 |
| GLI3 | GLI family zinc finger 3 |
| GOLGA8B | golgin A8 family, member B |
| GPR137B | G protein-coupled receptor 137B |
| GPR19 | G protein-coupled receptor 19 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2I | general transcription factor IIi |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H2AFJ | H2A histone family, member J |
| HEATR6 | HEAT repeat containing 6 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4C | histone cluster 1, H4c |
| HOXC11 | homeobox C11 |
| HOXC6 | homeobox C6 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIAA0556 | KIAA0556 |
| KIF18A | kinesin family member 18A |
| LAMA5 | laminin, alpha 5 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOC730101 | uncharacterized LOC730101 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| METTL21B | methyltransferase like 21B |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MICALL2 | MICAL-like 2 |
| MKL2 | MKL/myocardin-like 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NKRF | NFKB repressing factor |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| PCBP4 | poly(rC) binding protein 4 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLK2 | polo-like kinase 2 |
| PMP22 | peripheral myelin protein 22 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PROCR | protein C receptor, endothelial |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RGS16 | regulator of G-protein signaling 16 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RLN2 | relaxin 2 |
| RNF2 | ring finger protein 2 |
| SALL2 | spalt-like transcription factor 2 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SP140L | SP140 nuclear body protein-like |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| TMEM168 | transmembrane protein 168 |
| TMEM223 | transmembrane protein 223 |
| TMSB15A | thymosin beta 15a |
| TRPS1 | trichorhinophalangeal syndrome I |
| TUBA3D | tubulin, alpha 3d |
| TXNIP | thioredoxin interacting protein |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZIC1 | Zic family member 1 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF141 | zinc finger protein 141 |
| ZNF165 | zinc finger protein 165 |
| ZNF248 | zinc finger protein 248 |
| ZNF33B | zinc finger protein 33B |
| ZNF652 | zinc finger protein 652 |
| ZNF696 | zinc finger protein 696 |
| ZNF85 | zinc finger protein 85 |
