pathogen Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A biological agent that causes disease or illness to its host (Experimental Factor Ontology, EFO_0000643)
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Genes

93 genes co-occuring with the biological term pathogen in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AIM2 absent in melanoma 2
APOL1 apolipoprotein L, 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AVP arginine vasopressin
BPIFA1 BPI fold containing family A, member 1
BSG basigin (Ok blood group)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CAMP cathelicidin antimicrobial peptide
CCL17 chemokine (C-C motif) ligand 17
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD163 CD163 molecule
CD207 CD207 molecule, langerin
CD209 CD209 molecule
CD274 CD274 molecule
CD46 CD46 molecule, complement regulatory protein
CEL carboxyl ester lipase
CNOT8 CCR4-NOT transcription complex, subunit 8
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRNN cornulin
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR4 chemokine (C-X-C motif) receptor 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB4A defensin, beta 4A
DMBT1 deleted in malignant brain tumors 1
FCAR Fc fragment of IgA receptor
FLOT1 flotillin 1
FN1 fibronectin 1
FPR2 formyl peptide receptor 2
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGH immunoglobulin heavy locus
IL10 interleukin 10
IL17A interleukin 17A
IL1B interleukin 1, beta
IL6 interleukin 6
INS insulin
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LTF lactotransferrin
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCL1 myeloid cell leukemia 1
MEFV Mediterranean fever
MMP2 matrix metallopeptidase 2
NAIP NLR family, apoptosis inhibitory protein
NCAM1 neural cell adhesion molecule 1
NCR1 natural cytotoxicity triggering receptor 1
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
OXT oxytocin/neurophysin I prepropeptide
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PPARG peroxisome proliferator-activated receptor gamma
PRAME preferentially expressed antigen in melanoma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTX3 pentraxin 3, long
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SELE selectin E
SIGLEC7 sialic acid binding Ig-like lectin 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAT1 signal transducer and activator of transcription 1, 91kDa
SYK spleen tyrosine kinase
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TREM1 triggering receptor expressed on myeloid cells 1
TYROBP TYRO protein tyrosine kinase binding protein
VCP valosin containing protein
XDH xanthine dehydrogenase