pathogenesis Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The set of specific processes that generate the ability of an organism to cause disease in another. (Gene Ontology, GO_0009405)
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Genes

158 proteins co-occuring with the biological term pathogenesis in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACADVL acyl-CoA dehydrogenase, very long chain
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALK anaplastic lymphoma receptor tyrosine kinase
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATXN1 ataxin 1
ATXN10 ataxin 10
ATXN3 ataxin 3
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BTK Bruton agammaglobulinemia tyrosine kinase
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CDK1 cyclin-dependent kinase 1
CDK9 cyclin-dependent kinase 9
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCX doublecortin
DLG1 discs, large homolog 1 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DNM1L dynamin 1-like
DOK2 docking protein 2, 56kDa
DPYSL2 dihydropyrimidinase-like 2
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
FLNA filamin A, alpha
FOXA2 forkhead box A2
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GJA1 gap junction protein, alpha 1, 43kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HSPB1 heat shock 27kDa protein 1
HTRA2 HtrA serine peptidase 2
HTT huntingtin
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INPPL1 inositol polyphosphate phosphatase-like 1
INSR insulin receptor
IRS1 insulin receptor substrate 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KMT2A lysine (K)-specific methyltransferase 2A
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LEPR leptin receptor
LRP6 low density lipoprotein receptor-related protein 6
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MARK2 MAP/microtubule affinity-regulating kinase 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2D myocyte enhancer factor 2D
MID1 midline 1
MITF microphthalmia-associated transcription factor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
NCF1 neutrophil cytosolic factor 1
NCOR1 nuclear receptor corepressor 1
NF2 neurofibromin 2 (merlin)
NFE2L1 nuclear factor, erythroid 2-like 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSF N-ethylmaleimide-sensitive factor
PARK2 parkin RBR E3 ubiquitin protein ligase
PFN2 profilin 2
PHB prohibitin
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKM pyruvate kinase, muscle
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPARG peroxisome proliferator-activated receptor gamma
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRL prolactin
PRLR prolactin receptor
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPRA protein tyrosine phosphatase, receptor type, A
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS6 ribosomal protein S6
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR2 ryanodine receptor 2 (cardiac)
S100A9 S100 calcium binding protein A9
SGK1 serum/glucocorticoid regulated kinase 1
SIRT1 sirtuin 1
SNAPIN SNAP-associated protein
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCAIP synuclein, alpha interacting protein
SNCB synuclein, beta
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STK39 serine threonine kinase 39
STOML2 stomatin (EPB72)-like 2
TARDBP TAR DNA binding protein
TBK1 TANK-binding kinase 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TRAF3IP2 TRAF3 interacting protein 2
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
WWTR1 WW domain containing transcription regulator 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB16 zinc finger and BTB domain containing 16