pathologic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

260 genes co-occuring with the biological term pathologic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRE5 adhesion G protein-coupled receptor E5
ADK adenosine kinase
ADM adrenomedullin
ADORA2A adenosine A2a receptor
AGER advanced glycosylation end product-specific receptor
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALPL alkaline phosphatase, liver/bone/kidney
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA1 annexin A1
APAF1 apoptotic peptidase activating factor 1
APOC1 apolipoprotein C-I
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARX aristaless related homeobox
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B2M beta-2-microglobulin
BAG1 BCL2-associated athanogene
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRMS1 breast cancer metastasis suppressor 1
BSG basigin (Ok blood group)
C3 complement component 3
C4B complement component 4B (Chido blood group)
C9ORF72 chromosome 9 open reading frame 72
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD151 CD151 molecule (Raph blood group)
CD177 CD177 molecule
CD24 CD24 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDHR5 cadherin-related family member 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHAD chondroadherin
CHGA chromogranin A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC7A C-type lectin domain family 7, member A
CRP C-reactive protein, pentraxin-related
CRYAA crystallin, alpha A
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CTGF connective tissue growth factor
CTSB cathepsin B
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DIO2 deiodinase, iodothyronine, type II
DIO3 deiodinase, iodothyronine, type III
DMPK dystrophia myotonica-protein kinase
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DYSF dysferlin
EBAG9 estrogen receptor binding site associated, antigen, 9
ECT2 epithelial cell transforming 2
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2 coagulation factor II (thrombin)
FASLG Fas ligand (TNF superfamily, member 6)
FGF23 fibroblast growth factor 23
FGFR3 fibroblast growth factor receptor 3
FLNA filamin A, alpha
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FOXL1 forkhead box L1
FOXP1 forkhead box P1
FUS FUS RNA binding protein
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GJB2 gap junction protein, beta 2, 26kDa
GLUL glutamate-ammonia ligase
GNAS GNAS complex locus
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GRN granulin
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HAVCR1 hepatitis A virus cellular receptor 1
HDAC1 histone deacetylase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HOXB9 homeobox B9
HPCAL1 hippocalcin-like 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IDS iduronate 2-sulfatase
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL18R1 interleukin 18 receptor 1
IL1B interleukin 1, beta
IL33R interleukin 33 receptor
IL6 interleukin 6
JAK2 Janus kinase 2
JAM3 junctional adhesion molecule 3
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNK3 potassium channel, two pore domain subfamily K, member 3
KDR kinase insert domain receptor
KLK15 kallikrein-related peptidase 15
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS1 lectin, galactoside-binding, soluble, 1
LMX1B LIM homeobox transcription factor 1, beta
LOC643387 TAR DNA binding protein pseudogene
LRRK2 leucine-rich repeat kinase 2
MAML2 mastermind-like 2 (Drosophila)
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MED12 mediator complex subunit 12
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MIR155 microRNA 155
MIR214 microRNA 214
MKI67 marker of proliferation Ki-67
MLPH melanophilin
MME membrane metallo-endopeptidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSLN mesothelin
MTNR1A melatonin receptor 1A
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOD1 myogenic differentiation 1
MYOT myotilin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NKX2-5 NK2 homeobox 5
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NREP neuronal regeneration related protein
OPTN optineurin
OR51E2 olfactory receptor, family 51, subfamily E, member 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PAX2 paired box 2
PDGFB platelet-derived growth factor beta polypeptide
PDPN podoplanin
PEBP1 phosphatidylethanolamine binding protein 1
PGR progesterone receptor
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAC1 placenta-specific 1
PLAUR plasminogen activator, urokinase receptor
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCI protein kinase C, iota
PRNP prion protein
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTX3 pentraxin 3, long
RAB27A RAB27A, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RLN2 relaxin 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPGR retinitis pigmentosa GTPase regulator
RPTOR regulatory associated protein of MTOR, complex 1
RYR2 ryanodine receptor 2 (cardiac)
RYR3 ryanodine receptor 3
S1PR2 sphingosine-1-phosphate receptor 2
SELE selectin E
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOAT2 sterol O-acyltransferase 2
SOD1 superoxide dismutase 1, soluble
SPG11 spastic paraplegia 11 (autosomal recessive)
SPOP speckle-type POZ protein
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SST somatostatin
TAC1 tachykinin, precursor 1
TARDBP TAR DNA binding protein
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TIMP1 TIMP metallopeptidase inhibitor 1
TLR3 toll-like receptor 3
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TREM1 triggering receptor expressed on myeloid cells 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TTR transthyretin
TWIST1 twist family bHLH transcription factor 1
TYMS thymidylate synthetase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZEB1 zinc finger E-box binding homeobox 1