pathological gambling Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An impulse control disorder that involves the uncontrollable impulse to gamble, irrespective of the interference the behaviour has on the individual's life. (Human Disease Ontology, DOID_12399)
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Genes

50 genes co-occuring with the disease pathological gambling in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
DRD2 dopamine receptor D2 1.74688
DRD4 dopamine receptor D4 1.60011
EHD2 EH-domain containing 2 1.34504
DRD1 dopamine receptor D1 1.33632
DRD3 dopamine receptor D3 1.24515
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 1.22779
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.17464
FZD10 frizzled class receptor 10 1.03114
IFI44L interferon-induced protein 44-like 1.00879
PPP4C protein phosphatase 4, catalytic subunit 1.0071
MT1X metallothionein 1X 0.97254
FAIM2 Fas apoptotic inhibitory molecule 2 0.956614
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.927105
MAOA monoamine oxidase A 0.922974
ADRA2C adrenoceptor alpha 2C 0.903621
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.857315
LRG1 leucine-rich alpha-2-glycoprotein 1 0.838476
ANKK1 ankyrin repeat and kinase domain containing 1 0.833558
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 0.821667
MAOB monoamine oxidase B 0.803205
DRD5 dopamine receptor D5 0.771252
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.762271
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.741923
PPT1 palmitoyl-protein thioesterase 1 0.712796
COMT catechol-O-methyltransferase 0.711587
PTK7 protein tyrosine kinase 7 (inactive) 0.695905
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.67113
LPP LIM domain containing preferred translocation partner in lipoma 0.658026
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.650903
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.625711
VLDLR very low density lipoprotein receptor 0.624927
MBNL1 muscleblind-like splicing regulator 1 0.57655
SDF4 stromal cell derived factor 4 0.463149
GAL galanin/GMAP prepropeptide 0.361133
BDNF brain-derived neurotrophic factor 0.350452
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.348981
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.324823
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.323365
NAGS N-acetylglutamate synthase 0.321545
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.273664
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.263722
CAMP cathelicidin antimicrobial peptide 0.262306
FLNA filamin A, alpha 0.254183
CBS cystathionine-beta-synthase 0.226607
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.208245
PPY pancreatic polypeptide 0.187719
GGT2 gamma-glutamyltransferase 2 0.181222
C5ORF38 chromosome 5 open reading frame 38 0.164571
SST somatostatin 0.163523
AMH anti-Mullerian hormone 0.15948