pathological neovascularization Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description the proliferation of blood vessels in abnormal tissues or in abnormal positions (Mammalian Phenotype Ontology, MP_0003711)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003711
Similar Terms
Downloads & Tools

Genes

82 gene mutations causing the pathological neovascularization phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ANGPT2 angiopoietin 2
ANGPTL4 angiopoietin-like 4
ANPEP alanyl (membrane) aminopeptidase
APOE apolipoprotein E
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BCL2 B-cell CLL/lymphoma 2
BMPER BMP binding endothelial regulator
CBS cystathionine-beta-synthase
CCL13 chemokine (C-C motif) ligand 13
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CDH13 cadherin 13
CISD2 CDGSH iron sulfur domain 2
COL4A1 collagen, type IV, alpha 1
CSRP2BP CSRP2 binding protein
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
DLL4 delta-like 4 (Drosophila)
DSTN destrin (actin depolymerizing factor)
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
EDA ectodysplasin A
ERRFI1 ERBB receptor feedback inhibitor 1
F3 coagulation factor III (thromboplastin, tissue factor)
FIGN fidgetin
FLT1 fms-related tyrosine kinase 1
FOXC1 forkhead box C1
FOXE3 forkhead box E3
FOXN1 forkhead box N1
H2AFX H2A histone family, member X
HPSE heparanase
ICAM1 intercellular adhesion molecule 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNG interferon, gamma
IL10 interleukin 10
IL1RN interleukin 1 receptor antagonist
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KLHL20 kelch-like family member 20
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIF leukemia inhibitory factor
LIMK2 LIM domain kinase 2
LMX1B LIM homeobox transcription factor 1, beta
MCPH1 microcephalin 1
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MYH9 myosin, heavy chain 9, non-muscle
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOSTRIN nitric oxide synthase trafficking
NOTCH1 notch 1
NRARP NOTCH-regulated ankyrin repeat protein
NRP1 neuropilin 1
OPTC opticin
PAX6 paired box 6
PEX3 peroxisomal biogenesis factor 3
PGF placental growth factor
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLG plasminogen
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRDX6 peroxiredoxin 6
PRPH2 peripherin 2 (retinal degeneration, slow)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL24 ribosomal protein L24
SFRP2 secreted frizzled-related protein 2
SPNS2 spinster homolog 2 (Drosophila)
TGFA transforming growth factor, alpha
TMC8 transmembrane channel-like 8
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VEGFB vascular endothelial growth factor B
VLDLR very low density lipoprotein receptor