pathological Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

143 proteins co-occuring with the biological term pathological in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ADRBK1 adrenergic, beta, receptor kinase 1
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOL1 apolipoprotein L, 1
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASIC1 acid sensing (proton gated) ion channel 1
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAV1 caveolin 1, caveolae protein, 22kDa
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK5 cyclin-dependent kinase 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHEK1 checkpoint kinase 1
CREB1 cAMP responsive element binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
DAPK1 death-associated protein kinase 1
DLG4 discs, large homolog 4 (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EGFR epidermal growth factor receptor
ELK1 ELK1, member of ETS oncogene family
EPHA3 EPH receptor A3
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EZR ezrin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLT3 fms-related tyrosine kinase 3
FOXO3 forkhead box O3
FRS2 fibroblast growth factor receptor substrate 2
FTH1 ferritin, heavy polypeptide 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GATA4 GATA binding protein 4
GJA1 gap junction protein, alpha 1, 43kDa
GLI2 GLI family zinc finger 2
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H2AFX H2A histone family, member X
HDAC5 histone deacetylase 5
HRH1 histamine receptor H1
HSPB1 heat shock 27kDa protein 1
HTT huntingtin
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
IRS1 insulin receptor substrate 1
JUN jun proto-oncogene
KARS lysyl-tRNA synthetase
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KDR kinase insert domain receptor
KRT8 keratin 8, type II
LPCAT2 lysophosphatidylcholine acyltransferase 2
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MARK2 MAP/microtubule affinity-regulating kinase 2
MCU mitochondrial calcium uniporter
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLKL mixed lineage kinase domain-like
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MSN moesin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYL9 myosin, light chain 9, regulatory
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPRK1 opioid receptor, kappa 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PKN1 protein kinase N1
PLCG1 phospholipase C, gamma 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKD1 protein kinase D1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PXN paxillin
RACGAP1 Rac GTPase activating protein 1
RCAN1 regulator of calcineurin 1
RDX radixin
RIPK3 receptor-interacting serine-threonine kinase 3
RPL13A ribosomal protein L13a
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR2 ryanodine receptor 2 (cardiac)
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMC1A structural maintenance of chromosomes 1A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP1 Sp1 transcription factor
SPAG5 sperm associated antigen 5
SPHK1 sphingosine kinase 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STK4 serine/threonine kinase 4
STXBP1 syntaxin binding protein 1
SYN1 synapsin I
TARDBP TAR DNA binding protein
TEK TEK tyrosine kinase, endothelial
TH tyrosine hydroxylase
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TPPP tubulin polymerization promoting protein
TRAF1 TNF receptor-associated factor 1
TRIM28 tripartite motif containing 28
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VASP vasodilator-stimulated phosphoprotein
VAV3 vav 3 guanine nucleotide exchange factor
YAP1 Yes-associated protein 1