pathophysiological Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
Downloads & Tools

Genes

220 genes co-occuring with the biological term pathophysiological in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE2 angiotensin I converting enzyme 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR2 adiponectin receptor 2
ADM2 adrenomedullin 2
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANXA2 annexin A2
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ARHGAP22 Rho GTPase activating protein 22
BCHE butyrylcholinesterase
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
C9ORF72 chromosome 9 open reading frame 72
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCA calcitonin-related polypeptide alpha
CASQ2 calsequestrin 2 (cardiac muscle)
CCKBR cholecystokinin B receptor
CCL3 chemokine (C-C motif) ligand 3
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDT1 chromatin licensing and DNA replication factor 1
CEL carboxyl ester lipase
CLRN1 clarin 1
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CTSK cathepsin K
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCR1 chemokine (C-X-C motif) receptor 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAOA D-amino acid oxidase activator
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB4A defensin, beta 4A
DMD dystrophin
DNM2 dynamin 2
DRD1 dopamine receptor D1
EDN1 endothelin 1
ELAVL1 ELAV like RNA binding protein 1
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FBXO7 F-box protein 7
FLG filaggrin
FOXO3 forkhead box O3
FPR1 formyl peptide receptor 1
GATA2 GATA binding protein 2
GGT1 gamma-glutamyltransferase 1
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GNRHR gonadotropin-releasing hormone receptor
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP5 glycoprotein V (platelet)
GP9 glycoprotein IX (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPR55 G protein-coupled receptor 55
GRHL1 grainyhead-like 1 (Drosophila)
GRM3 glutamate receptor, metabotropic 3
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HABP2 hyaluronan binding protein 2
HBA1 hemoglobin, alpha 1
HCAR2 hydroxycarboxylic acid receptor 2
HEXIM1 hexamethylene bis-acetamide inducible 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HRG histidine-rich glycoprotein
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICAM1 intercellular adhesion molecule 1
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFNL1 interferon, lambda 1
IFNL2 interferon, lambda 2
IFNL3 interferon, lambda 3
IGFBP1 insulin-like growth factor binding protein 1
IL17A interleukin 17A
IL17F interleukin 17F
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL27 interleukin 27
IL32 interleukin 32
IL6 interleukin 6
INHBA inhibin, beta A
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KISS1 KiSS-1 metastasis-suppressor
KITLG KIT ligand
KLF6 Kruppel-like factor 6
LAMB1 laminin, beta 1
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LHCGR luteinizing hormone/choriogonadotropin receptor
LITAF lipopolysaccharide-induced TNF factor
LMNA lamin A/C
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MEDAG mesenteric estrogen-dependent adipogenesis
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR134 microRNA 134
MIR196A2 microRNA 196a-2
MIR208A microRNA 208a
MIR210 microRNA 210
MIR499A microRNA 499a
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MPP1 membrane protein, palmitoylated 1, 55kDa
MST1R macrophage stimulating 1 receptor
MTAP methylthioadenosine phosphorylase
MUC1 mucin 1, cell surface associated
NAMPT nicotinamide phosphoribosyltransferase
NEFM neurofilament, medium polypeptide
NKX2-5 NK2 homeobox 5
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPS neuropeptide S
NPSR1 neuropeptide S receptor 1
NPY1R neuropeptide Y receptor Y1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
NTF3 neurotrophin 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA1 optic atrophy 1 (autosomal dominant)
OPRD1 opioid receptor, delta 1
OPTN optineurin
PAEP progestagen-associated endometrial protein
PANX1 pannexin 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PML promyelocytic leukemia
PNPLA2 patatin-like phospholipase domain containing 2
PNPT1 polyribonucleotide nucleotidyltransferase 1
POMC proopiomelanocortin
PON1 paraoxonase 1
PON2 paraoxonase 2
PON3 paraoxonase 3
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRDX4 peroxiredoxin 4
PRNP prion protein
PTPRD protein tyrosine phosphatase, receptor type, D
PYY peptide YY
REG1A regenerating islet-derived 1 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RGN regucalcin
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RYK receptor-like tyrosine kinase
S100B S100 calcium binding protein B
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SIRT1 sirtuin 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SPP1 secreted phosphoprotein 1
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STC1 stanniocalcin 1
STK4 serine/threonine kinase 4
TAC1 tachykinin, precursor 1
TARDBP TAR DNA binding protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFF1 trefoil factor 1
TH tyrosine hydroxylase
TMEM109 transmembrane protein 109
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TXN thioredoxin
UBQLN2 ubiquilin 2
UTS2 urotensin 2
UTS2R urotensin 2 receptor
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
VWF von Willebrand factor
XBP1 X-box binding protein 1