pea15 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description phosphoprotein enriched in astrocytes 15|This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 8682)
Similar Terms
Downloads & Tools

Genes

9 genes co-occuring with the biological term pea15 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
HSPB1 heat shock 27kDa protein 1
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
PEA15 phosphoprotein enriched in astrocytes 15
PTEN phosphatase and tensin homolog
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3