pempidine-2172 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pempidine-2172 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACSL6 acyl-CoA synthetase long-chain family member 6
ADGRE1 adhesion G protein-coupled receptor E1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATP10B ATPase, class V, type 10B
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BCAS3 breast carcinoma amplified sequence 3
C14ORF1 chromosome 14 open reading frame 1
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CEP250 centrosomal protein 250kDa
CLTA clathrin, light chain A
CLU clusterin
COL10A1 collagen, type X, alpha 1
COPE coatomer protein complex, subunit epsilon
CREBZF CREB/ATF bZIP transcription factor
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DEFA4 defensin, alpha 4, corticostatin
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD2 dopamine receptor D2
ELOVL5 ELOVL fatty acid elongase 5
ELSPBP1 epididymal sperm binding protein 1
EML2 echinoderm microtubule associated protein like 2
FABP3 fatty acid binding protein 3, muscle and heart
FAM49A family with sequence similarity 49, member A
FAM49B family with sequence similarity 49, member B
FBXL2 F-box and leucine-rich repeat protein 2
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FXYD2 FXYD domain containing ion transport regulator 2
GRM1 glutamate receptor, metabotropic 1
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H3G histone cluster 1, H3g
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPB3 heat shock 27kDa protein 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IQSEC1 IQ motif and Sec7 domain 1
IRX4 iroquois homeobox 4
ISG20 interferon stimulated exonuclease gene 20kDa
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIFC3 kinesin family member C3
LAMP3 lysosomal-associated membrane protein 3
LINC00652 long intergenic non-protein coding RNA 652
LMF1 lipase maturation factor 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MECOM MDS1 and EVI1 complex locus
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MNX1 motor neuron and pancreas homeobox 1
MTMR8 myotubularin related protein 8
MXD4 MAX dimerization protein 4
MYOM1 myomesin 1
NCLN nicalin
NDRG2 NDRG family member 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NNAT neuronatin
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PDE10A phosphodiesterase 10A
PDGFB platelet-derived growth factor beta polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKNOX2 PBX/knotted 1 homeobox 2
PLCH1 phospholipase C, eta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLSCR4 phospholipid scramblase 4
PRSS53 protease, serine, 53
PSG1 pregnancy specific beta-1-glycoprotein 1
PXDC1 PX domain containing 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RDX radixin
REC8 REC8 meiotic recombination protein
RIN2 Ras and Rab interactor 2
RPL18 ribosomal protein L18
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIN3B SIN3 transcription regulator family member B
SKAP1 src kinase associated phosphoprotein 1
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC45A2 solute carrier family 45, member 2
SORBS3 sorbin and SH3 domain containing 3
SPRR2B small proline-rich protein 2B
SPTB spectrin, beta, erythrocytic
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SYN2 synapsin II
T T, brachyury homolog (mouse)
TBX6 T-box 6
TMEM140 transmembrane protein 140
TMOD1 tropomodulin 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNIK TRAF2 and NCK interacting kinase
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UTS2 urotensin 2
VEGFA vascular endothelial growth factor A
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX2 zinc finger homeobox 2

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRG2 adhesion G protein-coupled receptor G2
ANAPC2 anaphase promoting complex subunit 2
APH1B APH1B gamma secretase subunit
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
BATF basic leucine zipper transcription factor, ATF-like
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN15 calpain 15
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNT1 cyclin T1
CD320 CD320 molecule
CD37 CD37 molecule
CDA cytidine deaminase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP295 centrosomal protein 295kDa
CST3 cystatin C
CTRL chymotrypsin-like
DCAF13 DDB1 and CUL4 associated factor 13
DDN dendrin
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DGKG diacylglycerol kinase, gamma 90kDa
DOLK dolichol kinase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF5A2 eukaryotic translation initiation factor 5A2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FOSL1 FOS-like antigen 1
G6PD glucose-6-phosphate dehydrogenase
GALK1 galactokinase 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR22 G protein-coupled receptor 22
GRPR gastrin-releasing peptide receptor
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1E histone cluster 1, H1e
HMGB3P1 high mobility group box 3 pseudogene 1
HP1BP3 heterochromatin protein 1, binding protein 3
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD20 potassium channel tetramerization domain containing 20
KCTD7 potassium channel tetramerization domain containing 7
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIMS2 LIM and senescent cell antigen-like domains 2
LIN7A lin-7 homolog A (C. elegans)
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAK male germ cell-associated kinase
MDM4 MDM4, p53 regulator
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MOSPD3 motile sperm domain containing 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPS34 mitochondrial ribosomal protein S34
MVD mevalonate (diphospho) decarboxylase
NARFL nuclear prelamin A recognition factor-like
NCALD neurocalcin delta
NCS1 neuronal calcium sensor 1
NKX3-2 NK3 homeobox 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI2 peptidyl arginine deiminase, type II
PCDHGA10 protocadherin gamma subfamily A, 10
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PGM3 phosphoglucomutase 3
PGP phosphoglycolate phosphatase
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PLP1 proteolipid protein 1
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBM42 RNA binding motif protein 42
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAMP5 secretory carrier membrane protein 5
SCRN3 secernin 3
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SSBP3 single stranded DNA binding protein 3
STK25 serine/threonine kinase 25
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TESK1 testis-specific kinase 1
THEM6 thioesterase superfamily member 6
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM254 transmembrane protein 254
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TSPAN14 tetraspanin 14
UBIAD1 UbiA prenyltransferase domain containing 1
VSIG10 V-set and immunoglobulin domain containing 10
WNT16 wingless-type MMTV integration site family, member 16
ZBTB10 zinc finger and BTB domain containing 10
ZBTB22 zinc finger and BTB domain containing 22
ZNF219 zinc finger protein 219
ZNF34 zinc finger protein 34
ZNF606 zinc finger protein 606
ZNF668 zinc finger protein 668