| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pempidine-3832 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ARSD | arylsulfatase D |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C5AR1 | complement component 5a receptor 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLDN11 | claudin 11 |
| CLEC4A | C-type lectin domain family 4, member A |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COL1A1 | collagen, type I, alpha 1 |
| CPA4 | carboxypeptidase A4 |
| CPNE7 | copine VII |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYTH1 | cytohesin 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIXDC1 | DIX domain containing 1 |
| EPS8L3 | EPS8-like 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| ESR1 | estrogen receptor 1 |
| EZR | ezrin |
| FSTL1 | follistatin-like 1 |
| FUT9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
| GATA4 | GATA binding protein 4 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| HIST1H2BB | histone cluster 1, H2bb |
| HOXA11 | homeobox A11 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IRS4 | insulin receptor substrate 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KITLG | KIT ligand |
| KLF8 | Kruppel-like factor 8 |
| KLHL25 | kelch-like family member 25 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCOLN1 | mucolipin 1 |
| MED27 | mediator complex subunit 27 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MZF1 | myeloid zinc finger 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NMT1 | N-myristoyltransferase 1 |
| NOX1 | NADPH oxidase 1 |
| NUP188 | nucleoporin 188kDa |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PAX8 | paired box 8 |
| PCM1 | pericentriolar material 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PGAP3 | post-GPI attachment to proteins 3 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLK3 | polo-like kinase 3 |
| PLXNB3 | plexin B3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PXDC1 | PX domain containing 1 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RBM34 | RNA binding motif protein 34 |
| RGS12 | regulator of G-protein signaling 12 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPL10 | ribosomal protein L10 |
| RRBP1 | ribosome binding protein 1 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLAMF8 | SLAM family member 8 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SP1 | Sp1 transcription factor |
| SPPL2B | signal peptide peptidase like 2B |
| SSTR2 | somatostatin receptor 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TNPO2 | transportin 2 |
| TOP3B | topoisomerase (DNA) III beta |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TTC39A | tetratricopeptide repeat domain 39A |
| TWF1 | twinfilin actin binding protein 1 |
| UROD | uroporphyrinogen decarboxylase |
| VEGFA | vascular endothelial growth factor A |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WSCD1 | WSC domain containing 1 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADCY7 | adenylate cyclase 7 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APOD | apolipoprotein D |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C4BPA | complement component 4 binding protein, alpha |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALML5 | calmodulin-like 5 |
| CCDC25 | coiled-coil domain containing 25 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CXORF56 | chromosome X open reading frame 56 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DMTN | dematin actin binding protein |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYM | dymeclin |
| EFNA3 | ephrin-A3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLB1L | galactosidase, beta 1-like |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H4C | histone cluster 1, H4c |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| IFNA14 | interferon, alpha 14 |
| IL22 | interleukin 22 |
| IRF1 | interferon regulatory factor 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JADE3 | jade family PHD finger 3 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA1107 | KIAA1107 |
| KRT16 | keratin 16, type I |
| LAMA3 | laminin, alpha 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LHX1 | LIM homeobox 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPXN | leupaxin |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MFAP2 | microfibrillar-associated protein 2 |
| MGC12488 | |
| MMP2 | matrix metallopeptidase 2 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PCDHB3 | protocadherin beta 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POLM | polymerase (DNA directed), mu |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRPH | peripherin |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QSER1 | glutamine and serine rich 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RNF208 | ring finger protein 208 |
| RRAGB | Ras-related GTP binding B |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC35E3 | solute carrier family 35, member E3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPAG4 | sperm associated antigen 4 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STX1A | syntaxin 1A (brain) |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TFF2 | trefoil factor 2 |
| TLN1 | talin 1 |
| TMC5 | transmembrane channel-like 5 |
| TONSL | tonsoku-like, DNA repair protein |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBA3C | tubulin, alpha 3c |
| TYRP1 | tyrosinase-related protein 1 |
| UPK2 | uroplakin 2 |
| USP6NL | USP6 N-terminal like |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF358 | zinc finger protein 358 |
| ZNF442 | zinc finger protein 442 |
| ZNF639 | zinc finger protein 639 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
