pempidine-4307 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pempidine-4307 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADGRG1 adhesion G protein-coupled receptor G1
ADRA1A adrenoceptor alpha 1A
AGRN agrin
APOE apolipoprotein E
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BATF basic leucine zipper transcription factor, ATF-like
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CASZ1 castor zinc finger 1
CBS cystathionine-beta-synthase
CCL27 chemokine (C-C motif) ligand 27
CD34 CD34 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFAP69 cilia and flagella associated protein 69
CFAP70 cilia and flagella associated protein 70
CLCN4 chloride channel, voltage-sensitive 4
CLTA clathrin, light chain A
COL8A1 collagen, type VIII, alpha 1
CPZ carboxypeptidase Z
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DKFZP434C153 DKFZP434C153 protein
DPY19L1P1 DPY19L1 pseudogene 1
EXPH5 exophilin 5
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF16 fibroblast growth factor 16
FGFR4 fibroblast growth factor receptor 4
FKBP1A FK506 binding protein 1A, 12kDa
GGT1 gamma-glutamyltransferase 1
GPR19 G protein-coupled receptor 19
GRIK5 glutamate receptor, ionotropic, kainate 5
H2AFX H2A histone family, member X
HFE hemochromatosis
HPX hemopexin
HRASLS2 HRAS-like suppressor 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL12B interleukin 12B
IQCC IQ motif containing C
IQSEC2 IQ motif and Sec7 domain 2
JAK3 Janus kinase 3
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF4 Kruppel-like factor 4 (gut)
KLHL25 kelch-like family member 25
LEF1 lymphoid enhancer-binding factor 1
LIME1 Lck interacting transmembrane adaptor 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MED25 mediator complex subunit 25
NDRG4 NDRG family member 4
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PASK PAS domain containing serine/threonine kinase
PBX1 pre-B-cell leukemia homeobox 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4A phosphodiesterase 4A, cAMP-specific
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PER1 period circadian clock 1
PGP phosphoglycolate phosphatase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCH1 phospholipase C, eta 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PROX1 prospero homeobox 1
PRTN3 proteinase 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB28 RAB28, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAPSN receptor-associated protein of the synapse
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS4 regulator of G-protein signaling 4
RNF126P1 ring finger protein 126 pseudogene 1
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPRED2 sprouty-related, EVH1 domain containing 2
SSX1 synovial sarcoma, X breakpoint 1
STATH statherin
SZT2 seizure threshold 2 homolog (mouse)
TBC1D22B TBC1 domain family, member 22B
TBR1 T-box, brain, 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCP11L1 t-complex 11, testis-specific-like 1
TEF thyrotrophic embryonic factor
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TM4SF5 transmembrane 4 L six family member 5
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRAF3IP3 TRAF3 interacting protein 3
TRIM15 tripartite motif containing 15
TRIM3 tripartite motif containing 3
WDR55 WD repeat domain 55
WFDC2 WAP four-disulfide core domain 2
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF407 zinc finger protein 407
ZNF549 zinc finger protein 549
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ACVR2B activin A receptor, type IIB
ADGRB2 adhesion G protein-coupled receptor B2
ADGRF1 adhesion G protein-coupled receptor F1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD36 ankyrin repeat domain 36
ASAP1-IT1 ASAP1 intronic transcript 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C17ORF53 chromosome 17 open reading frame 53
C17ORF70 chromosome 17 open reading frame 70
C5ORF45 chromosome 5 open reading frame 45
C9ORF9 chromosome 9 open reading frame 9
CCDC71 coiled-coil domain containing 71
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP295 centrosomal protein 295kDa
CES3 carboxylesterase 3
CTC1 CTS telomere maintenance complex component 1
CUEDC1 CUE domain containing 1
CXCL3 chemokine (C-X-C motif) ligand 3
DBF4B DBF4 zinc finger B
DCAF16 DDB1 and CUL4 associated factor 16
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC4 excision repair cross-complementation group 4
FBXL7 F-box and leucine-rich repeat protein 7
FBXW12 F-box and WD repeat domain containing 12
FKBP14 FK506 binding protein 14, 22 kDa
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HINFP histone H4 transcription factor
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2BM histone cluster 1, H2bm
HIST1H4C histone cluster 1, H4c
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IFI6 interferon, alpha-inducible protein 6
IRAK4 interleukin-1 receptor-associated kinase 4
KIRREL kin of IRRE like (Drosophila)
LOC730101 uncharacterized LOC730101
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP2 low density lipoprotein receptor-related protein 2
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A3 leucine rich repeat containing 37, member A3
MAGEA6 melanoma antigen family A6
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MIS18BP1 MIS18 binding protein 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NUP62CL nucleoporin 62kDa C-terminal like
PAIP2B poly(A) binding protein interacting protein 2B
PCYOX1 prenylcysteine oxidase 1
PGPEP1 pyroglutamyl-peptidase I
PMCH pro-melanin-concentrating hormone
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR14L proline rich 14-like
PTPRH protein tyrosine phosphatase, receptor type, H
PWAR5 Prader Willi/Angelman region RNA 5
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFWD3 ring finger and WD repeat domain 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIDR scaffolding protein involved in DNA repair
SPIN1 spindlin 1
SPRYD7 SPRY domain containing 7
STRA6 stimulated by retinoic acid 6
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNC syncoilin, intermediate filament protein
TAOK1 TAO kinase 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TTBK2 tau tubulin kinase 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
VN1R1 vomeronasal 1 receptor 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB38 zinc finger and BTB domain containing 38
ZNF124 zinc finger protein 124
ZNF160 zinc finger protein 160
ZNF426 zinc finger protein 426
ZNF652 zinc finger protein 652
ZNF667 zinc finger protein 667
ZNF668 zinc finger protein 668
ZNF669 zinc finger protein 669
ZNF721 zinc finger protein 721
ZNF74 zinc finger protein 74
ZNF91 zinc finger protein 91