pempidine-6027 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pempidine-6027 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADCK4 aarF domain containing kinase 4
AGFG2 ArfGAP with FG repeats 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ATN1 atrophin 1
C11ORF21 chromosome 11 open reading frame 21
C14ORF105 chromosome 14 open reading frame 105
C14ORF79 chromosome 14 open reading frame 79
CAMKV CaM kinase-like vesicle-associated
CCL24 chemokine (C-C motif) ligand 24
CCL27 chemokine (C-C motif) ligand 27
CCRL2 chemokine (C-C motif) receptor-like 2
CD1C CD1c molecule
CD52 CD52 molecule
CD70 CD70 molecule
CDA cytidine deaminase
CEP112 centrosomal protein 112kDa
CEP250 centrosomal protein 250kDa
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CLIP2 CAP-GLY domain containing linker protein 2
DEFB1 defensin, beta 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK4 docking protein 4
DTNB dystrobrevin, beta
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EGFL7 EGF-like-domain, multiple 7
ERC2-IT1 ERC2 intronic transcript 1
ETV7 ets variant 7
FABP3 fatty acid binding protein 3, muscle and heart
FAM66D family with sequence similarity 66, member D
FGF6 fibroblast growth factor 6
FSHB follicle stimulating hormone, beta polypeptide
FSTL1 follistatin-like 1
GH1 growth hormone 1
GPR137 G protein-coupled receptor 137
GRIA4 glutamate receptor, ionotropic, AMPA 4
HOXB3 homeobox B3
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL13 interleukin 13
IL33R interleukin 33 receptor
ING4 inhibitor of growth family, member 4
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA9 integrin, alpha 9
JAG1 jagged 1
KALRN kalirin, RhoGEF kinase
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0485 uncharacterized LOC57235
KIF1C kinesin family member 1C
KLHL24 kelch-like family member 24
KLHL25 kelch-like family member 25
KRT2 keratin 2, type II
LOC100131532 uncharacterized LOC100131532
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LTB4R leukotriene B4 receptor
LUZP4 leucine zipper protein 4
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK14 mitogen-activated protein kinase 14
MEGF6 multiple EGF-like-domains 6
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MNDA myeloid cell nuclear differentiation antigen
MYL10 myosin, light chain 10, regulatory
MYO7B myosin VIIB
MYRIP myosin VIIA and Rab interacting protein
NKX2-5 NK2 homeobox 5
NRF1 nuclear respiratory factor 1
OPCML opioid binding protein/cell adhesion molecule-like
OPRK1 opioid receptor, kappa 1
PAX3 paired box 3
PCDHB17P protocadherin beta 17 pseudogene
PCDHGA11 protocadherin gamma subfamily A, 11
PDLIM7 PDZ and LIM domain 7 (enigma)
PNMAL1 paraneoplastic Ma antigen family-like 1
PRMT8 protein arginine methyltransferase 8
PSCA prostate stem cell antigen
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RASAL2 RAS protein activator like 2
RECQL5 RecQ protein-like 5
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCRT1 scratch family zinc finger 1
SECTM1 secreted and transmembrane 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SNED1 sushi, nidogen and EGF-like domains 1
SSX1 synovial sarcoma, X breakpoint 1
STAB1 stabilin 1
STS steroid sulfatase (microsomal), isozyme S
SYT11 synaptotagmin XI
T T, brachyury homolog (mouse)
TAOK2 TAO kinase 2
TAPBP TAP binding protein (tapasin)
TBCD tubulin folding cofactor D
TM4SF5 transmembrane 4 L six family member 5
TPM1 tropomyosin 1 (alpha)
TPMT thiopurine S-methyltransferase
TRD T cell receptor delta locus

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
C12ORF4 chromosome 12 open reading frame 4
C1ORF159 chromosome 1 open reading frame 159
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNO cyclin O
CD3EAP CD3e molecule, epsilon associated protein
CDK20 cyclin-dependent kinase 20
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP7 charged multivesicular body protein 7
CRYGC crystallin, gamma C
CTSF cathepsin F
DDIT3 DNA-damage-inducible transcript 3
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DOC2A double C2-like domains, alpha
DUSP2 dual specificity phosphatase 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHA2 EPH receptor A2
FAM155B family with sequence similarity 155, member B
FAM169A family with sequence similarity 169, member A
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FKBP14 FK506 binding protein 14, 22 kDa
FOXN2 forkhead box N2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GSTCD glutathione S-transferase, C-terminal domain containing
HOXC13 homeobox C13
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPA1L heat shock 70kDa protein 1-like
IFRD1 interferon-related developmental regulator 1
IFT81 intraflagellar transport 81
IPO13 importin 13
IRF6 interferon regulatory factor 6
JMJD4 jumonji domain containing 4
KREMEN2 kringle containing transmembrane protein 2
LIG4 ligase IV, DNA, ATP-dependent
LRRC61 leucine rich repeat containing 61
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
METTL16 methyltransferase like 16
MIR22HG MIR22 host gene
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NRSN2 neurensin 2
OSGIN1 oxidative stress induced growth inhibitor 1
PER3 period circadian clock 3
PGBD5 piggyBac transposable element derived 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PORCN porcupine homolog (Drosophila)
PRICKLE3 prickle homolog 3 (Drosophila)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD51AP1 RAD51 associated protein 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
SETD8 SET domain containing (lysine methyltransferase) 8
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SPAG4 sperm associated antigen 4
STRA6 stimulated by retinoic acid 6
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TESC tescalcin
TH tyrosine hydroxylase
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TPST2 tyrosylprotein sulfotransferase 2
TRIM62 tripartite motif containing 62
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC14 zinc finger, DHHC-type containing 14
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF532 zinc finger protein 532
ZSCAN26 zinc finger and SCAN domain containing 26