| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the penbutolol-2972 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ATXN2L | ataxin 2-like |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CD200 | CD200 molecule |
| CDC14A | cell division cycle 14A |
| CDK6 | cyclin-dependent kinase 6 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEP164 | centrosomal protein 164kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DEPDC5 | DEP domain containing 5 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ENO3 | enolase 3 (beta, muscle) |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FOXO1 | forkhead box O1 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPR132 | G protein-coupled receptor 132 |
| GTPBP4 | GTP binding protein 4 |
| HABP4 | hyaluronan binding protein 4 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4E | histone cluster 1, H4e |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IL5RA | interleukin 5 receptor, alpha |
| KHK | ketohexokinase (fructokinase) |
| KLHL22 | kelch-like family member 22 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGED2 | melanoma antigen family D2 |
| MAX | MYC associated factor X |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MIR22HG | MIR22 host gene |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NF2 | neurofibromin 2 (merlin) |
| NOX1 | NADPH oxidase 1 |
| NUP188 | nucleoporin 188kDa |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PCDH9 | protocadherin 9 |
| PDAP1 | PDGFA associated protein 1 |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLCD1 | phospholipase C, delta 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTAFR | platelet-activating factor receptor |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| PYGB | phosphorylase, glycogen; brain |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB6A | RAB6A, member RAS oncogene family |
| REC8 | REC8 meiotic recombination protein |
| RORA | RAR-related orphan receptor A |
| RPS28 | ribosomal protein S28 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMAD3 | SMAD family member 3 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTB | spectrin, beta, erythrocytic |
| SURF1 | surfeit 1 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TBRG4 | transforming growth factor beta regulator 4 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCF3 | transcription factor 3 |
| THTPA | thiamine triphosphatase |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM63A | transmembrane protein 63A |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIM16 | tripartite motif containing 16 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| USP53 | ubiquitin specific peptidase 53 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZNF446 | zinc finger protein 446 |
| ZNF512B | zinc finger protein 512B |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADORA3 | adenosine A3 receptor |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| BEND5 | BEN domain containing 5 |
| BNC2 | basonuclin 2 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC186 | coiled-coil domain containing 186 |
| CDCP1 | CUB domain containing protein 1 |
| CEP97 | centrosomal protein 97kDa |
| CES3 | carboxylesterase 3 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLGN | calmegin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRYL1 | crystallin, lambda 1 |
| DDN | dendrin |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DVL1 | dishevelled segment polarity protein 1 |
| EPHA4 | EPH receptor A4 |
| FBXO31 | F-box protein 31 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FHL3 | four and a half LIM domains 3 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GID4 | GID complex subunit 4 |
| GK3P | glycerol kinase 3 pseudogene |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4D | histone cluster 1, H4d |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HP | haptoglobin |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT81 | intraflagellar transport 81 |
| IL24 | interleukin 24 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPP | intracisternal A particle-promoted polypeptide |
| ITGA10 | integrin, alpha 10 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MICALL2 | MICAL-like 2 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NKX3-2 | NK3 homeobox 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDGFD | platelet derived growth factor D |
| PDLIM1 | PDZ and LIM domain 1 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PMP22 | peripheral myelin protein 22 |
| PNOC | prepronociceptin |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS13 | regulator of G-protein signaling 13 |
| RHOB | ras homolog family member B |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SERINC5 | serine incorporator 5 |
| SHPK | sedoheptulokinase |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPAG4 | sperm associated antigen 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| THEM6 | thioesterase superfamily member 6 |
| TMEM120B | transmembrane protein 120B |
| TMEM53 | transmembrane protein 53 |
| TRAF1 | TNF receptor-associated factor 1 |
| TUFT1 | tuftelin 1 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF215 | zinc finger protein 215 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
