| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the penbutolol-3534 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRA1A | adrenoceptor alpha 1A |
| ADRA1D | adrenoceptor alpha 1D |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATF3 | activating transcription factor 3 |
| ATN1 | atrophin 1 |
| ATXN3 | ataxin 3 |
| BCAP29 | B-cell receptor-associated protein 29 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BNC2 | basonuclin 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CCDC28B | coiled-coil domain containing 28B |
| CDC25C | cell division cycle 25C |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CFHR4 | complement factor H-related 4 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DOC2B | double C2-like domains, beta |
| DTNA | dystrobrevin, alpha |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ELMO2 | engulfment and cell motility 2 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ETV4 | ets variant 4 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLOT1 | flotillin 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALR3 | galanin receptor 3 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H4C | histone cluster 1, H4c |
| HLA-G | major histocompatibility complex, class I, G |
| HMOX1 | heme oxygenase 1 |
| HNF1A | HNF1 homeobox A |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT140 | intraflagellar transport 140 |
| INHBE | inhibin, beta E |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1107 | KIAA1107 |
| KLHL22 | kelch-like family member 22 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEB | nebulin |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPEPL1 | aminopeptidase-like 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PAPOLA | poly(A) polymerase alpha |
| PHF1 | PHD finger protein 1 |
| PHF14 | PHD finger protein 14 |
| PIDD1 | p53-induced death domain protein 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAU | plasminogen activator, urokinase |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRR4 | proline rich 4 (lacrimal) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIN1 | Ras and Rab interactor 1 |
| RPS2 | ribosomal protein S2 |
| RPS3A | ribosomal protein S3A |
| S100A11 | S100 calcium binding protein A11 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SETD1A | SET domain containing 1A |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPEG | SPEG complex locus |
| SQLE | squalene epoxidase |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STRN | striatin, calmodulin binding protein |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TBC1D17 | TBC1 domain family, member 17 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM259 | transmembrane protein 259 |
| TMEM63A | transmembrane protein 63A |
| TNXB | tenascin XB |
| TREX1 | three prime repair exonuclease 1 |
| UPK2 | uroplakin 2 |
| ZNF609 | zinc finger protein 609 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADM | adrenomedullin |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BAG4 | BCL2-associated athanogene 4 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CASZ1 | castor zinc finger 1 |
| CCDC121 | coiled-coil domain containing 121 |
| CLDN15 | claudin 15 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| DAGLA | diacylglycerol lipase, alpha |
| EN2 | engrailed homeobox 2 |
| EPHA2 | EPH receptor A2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FLNC | filamin C, gamma |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AI | histone cluster 1, H2ai |
| KIAA0319L | KIAA0319-like |
| LHX6 | LIM homeobox 6 |
| LOC730101 | uncharacterized LOC730101 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAP6D1 | MAP6 domain containing 1 |
| MBTD1 | mbt domain containing 1 |
| MCC | mutated in colorectal cancers |
| MFAP2 | microfibrillar-associated protein 2 |
| MGC12488 | |
| MITF | microphthalmia-associated transcription factor |
| MMP2 | matrix metallopeptidase 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ODF2 | outer dense fiber of sperm tails 2 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT2 | one cut homeobox 2 |
| PALM | paralemmin |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PC | pyruvate carboxylase |
| PCDHA9 | protocadherin alpha 9 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POPDC3 | popeye domain containing 3 |
| PROCR | protein C receptor, endothelial |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRR14L | proline rich 14-like |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTDSS2 | phosphatidylserine synthase 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUNDC3B | RUN domain containing 3B |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAI | suppressor of cancer cell invasion |
| SCRN3 | secernin 3 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC41A3 | solute carrier family 41, member 3 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STIM1 | stromal interaction molecule 1 |
| STXBP2 | syntaxin binding protein 2 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAOK1 | TAO kinase 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM45A | transmembrane protein 45A |
| TRAIP | TRAF interacting protein |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3D | tubulin, alpha 3d |
| UBQLN4 | ubiquilin 4 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF324 | zinc finger protein 324 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| ZNF696 | zinc finger protein 696 |
| ZNF721 | zinc finger protein 721 |
