| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the penbutolol-7476 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANKRD26 | ankyrin repeat domain 26 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATF3 | activating transcription factor 3 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B9D2 | B9 protein domain 2 |
| BTG2 | BTG family, member 2 |
| C5AR2 | complement component 5a receptor 2 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCDC64 | coiled-coil domain containing 64 |
| CDC14A | cell division cycle 14A |
| CLDN9 | claudin 9 |
| CLTA | clathrin, light chain A |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DMPK | dystrophia myotonica-protein kinase |
| DNPEP | aspartyl aminopeptidase |
| DUSP4 | dual specificity phosphatase 4 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FAAH | fatty acid amide hydrolase |
| FAM155A | family with sequence similarity 155, member A |
| FAM65A | family with sequence similarity 65, member A |
| FSTL4 | follistatin-like 4 |
| GAS7 | growth arrest-specific 7 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR153 | G protein-coupled receptor 153 |
| HEMK1 | HemK methyltransferase family member 1 |
| HHAT | hedgehog acyltransferase |
| HIST1H2BN | histone cluster 1, H2bn |
| HLA-C | major histocompatibility complex, class I, C |
| HLA-E | major histocompatibility complex, class I, E |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL11 | interleukin 11 |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JAK2 | Janus kinase 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KDM2A | lysine (K)-specific demethylase 2A |
| KIAA0355 | KIAA0355 |
| KLHL22 | kelch-like family member 22 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1A | microtubule-associated protein 1A |
| MAPK14 | mitogen-activated protein kinase 14 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MTCP1 | mature T-cell proliferation 1 |
| MZF1 | myeloid zinc finger 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PARD6B | par-6 family cell polarity regulator beta |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLXNB1 | plexin B1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB40C | RAB40C, member RAS oncogene family |
| RECQL5 | RecQ protein-like 5 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SERHL2 | serine hydrolase-like 2 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SHARPIN | SHANK-associated RH domain interactor |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAT5B | signal transducer and activator of transcription 5B |
| STK11 | serine/threonine kinase 11 |
| STK17B | serine/threonine kinase 17b |
| TBC1D2B | TBC1 domain family, member 2B |
| TFIP11 | tuftelin interacting protein 11 |
| THBD | thrombomodulin |
| TOP3B | topoisomerase (DNA) III beta |
| TRIL | TLR4 interactor with leucine-rich repeats |
| VEGFB | vascular endothelial growth factor B |
| VN1R1 | vomeronasal 1 receptor 1 |
| YY1 | YY1 transcription factor |
| ZNF134 | zinc finger protein 134 |
| ZNF442 | zinc finger protein 442 |
| ZNF484 | zinc finger protein 484 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ACVR2A | activin A receptor, type IIA |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| BAG4 | BCL2-associated athanogene 4 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAPN15 | calpain 15 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD82 | CD82 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CFD | complement factor D (adipsin) |
| CHKB | choline kinase beta |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL4A5 | collagen, type IV, alpha 5 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNM1 | dynamin 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXO31 | F-box protein 31 |
| FOXC1 | forkhead box C1 |
| FOXD1 | forkhead box D1 |
| FUZ | fuzzy planar cell polarity protein |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR27 | G protein-coupled receptor 27 |
| GPX2 | glutathione peroxidase 2 |
| HDAC4 | histone deacetylase 4 |
| HIST1H2AG | histone cluster 1, H2ag |
| HTRA1 | HtrA serine peptidase 1 |
| IL17RA | interleukin 17 receptor A |
| IL4R | interleukin 4 receptor |
| IMPACT | impact RWD domain protein |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF6 | interferon regulatory factor 6 |
| IRF7 | interferon regulatory factor 7 |
| LOC642236 | FSHD region gene 1 pseudogene |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBTD1 | mbt domain containing 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| METTL8 | methyltransferase like 8 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MXD3 | MAX dimerization protein 3 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NLRX1 | NLR family member X1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PER3 | period circadian clock 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLEK2 | pleckstrin 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PVRL3 | poliovirus receptor-related 3 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| SAV1 | salvador family WW domain containing protein 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAG3 | stromal antigen 3 |
| TCTN1 | tectonic family member 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TMSB15A | thymosin beta 15a |
| TSPYL2 | TSPY-like 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| UBXN6 | UBX domain protein 6 |
| USB1 | U6 snRNA biogenesis 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VEGFC | vascular endothelial growth factor C |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF219 | zinc finger protein 219 |
| ZNF226 | zinc finger protein 226 |
| ZNF254 | zinc finger protein 254 |
| ZNF273 | zinc finger protein 273 |
| ZNF280D | zinc finger protein 280D |
| ZNF324 | zinc finger protein 324 |
| ZNF365 | zinc finger protein 365 |
| ZNF768 | zinc finger protein 768 |
