| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the pentamidine-2473 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACAN | aggrecan |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BMP5 | bone morphogenetic protein 5 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C6 | complement component 6 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD5 | CD5 molecule |
| CDC42 | cell division cycle 42 |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLIC5 | chloride intracellular channel 5 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CPB2 | carboxypeptidase B2 (plasma) |
| CREM | cAMP responsive element modulator |
| CRMP1 | collapsin response mediator protein 1 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| EXOSC2 | exosome component 2 |
| FN1 | fibronectin 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IFNA17 | interferon, alpha 17 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL36 | kelch-like family member 36 |
| KRT9 | keratin 9, type I |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMF1 | lipase maturation factor 1 |
| LOX | lysyl oxidase |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MYO7B | myosin VIIB |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| MYOZ3 | myozenin 3 |
| NEUROD4 | neuronal differentiation 4 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOX1 | NADPH oxidase 1 |
| NPAS2 | neuronal PAS domain protein 2 |
| NPR1 | natriuretic peptide receptor 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NXPH4 | neurexophilin 4 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHF8 | PHD finger protein 8 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| POU2F2 | POU class 2 homeobox 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAMEF11 | PRAME family member 11 |
| PURG | purine-rich element binding protein G |
| RAB26 | RAB26, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RANBP1 | RAN binding protein 1 |
| RBP4 | retinol binding protein 4, plasma |
| REST | RE1-silencing transcription factor |
| RHAG | Rh-associated glycoprotein |
| RUFY3 | RUN and FYVE domain containing 3 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SH2D4A | SH2 domain containing 4A |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SSH3 | slingshot protein phosphatase 3 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TFF2 | trefoil factor 2 |
| THTPA | thiamine triphosphatase |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRPV5 | transient receptor potential cation channel, subfamily V, member 5 |
| TSGA10 | testis specific, 10 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TWF1 | twinfilin actin binding protein 1 |
| WDR55 | WD repeat domain 55 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF235 | zinc finger protein 235 |
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AEN | apoptosis enhancing nuclease |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALS2CL | ALS2 C-terminal like |
| AMDHD2 | amidohydrolase domain containing 2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ATG2B | autophagy related 2B |
| ATG4A | autophagy related 4A, cysteine peptidase |
| AXIN1 | axin 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CARF | calcium responsive transcription factor |
| CD1D | CD1d molecule |
| CDC37L1 | cell division cycle 37-like 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CFP | complement factor properdin |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLEC2D | C-type lectin domain family 2, member D |
| CLEC7A | C-type lectin domain family 7, member A |
| CTSO | cathepsin O |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNM3 | dynamin 3 |
| DSPP | dentin sialophosphoprotein |
| DYSF | dysferlin |
| ENAH | enabled homolog (Drosophila) |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| G0S2 | G0/G1 switch 2 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GID4 | GID complex subunit 4 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL22 | interleukin 22 |
| INO80D | INO80 complex subunit D |
| IREB2 | iron-responsive element binding protein 2 |
| JADE3 | jade family PHD finger 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA1107 | KIAA1107 |
| KPTN | kaptin (actin binding protein) |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSP1 | lymphocyte-specific protein 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP9 | matrix metallopeptidase 9 |
| MREG | melanoregulin |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PANX1 | pannexin 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PODXL2 | podocalyxin-like 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS53 | protease, serine, 53 |
| PYGB | phosphorylase, glycogen; brain |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SNX15 | sorting nexin 15 |
| SPON2 | spondin 2, extracellular matrix protein |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| TAOK1 | TAO kinase 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR4 | toll-like receptor 4 |
| TMEM254 | transmembrane protein 254 |
| TMEM53 | transmembrane protein 53 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRIM25 | tripartite motif containing 25 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TXLNG | taxilin gamma |
| WDR62 | WD repeat domain 62 |
| XAB2 | XPA binding protein 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF155 | zinc finger protein 155 |
| ZNF197 | zinc finger protein 197 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF528 | zinc finger protein 528 |
| ZNF804A | zinc finger protein 804A |
