| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the pentamidine-2834 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APC | adenomatous polyposis coli |
| APOM | apolipoprotein M |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATP10B | ATPase, class V, type 10B |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| AUTS2 | autism susceptibility candidate 2 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C3AR1 | complement component 3a receptor 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD177 | CD177 molecule |
| CD58 | CD58 molecule |
| CD82 | CD82 molecule |
| CDC14B | cell division cycle 14B |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CRMP1 | collapsin response mediator protein 1 |
| CROT | carnitine O-octanoyltransferase |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DUSP10 | dual specificity phosphatase 10 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPOR | erythropoietin receptor |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM174B | family with sequence similarity 174, member B |
| FAM50B | family with sequence similarity 50, member B |
| FGFR1 | fibroblast growth factor receptor 1 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| IL23A | interleukin 23, alpha subunit p19 |
| KLHL22 | kelch-like family member 22 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| MAOB | monoamine oxidase B |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR622 | microRNA 622 |
| MITF | microphthalmia-associated transcription factor |
| MST1 | macrophage stimulating 1 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NCOA2 | nuclear receptor coactivator 2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDRG2 | NDRG family member 2 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PLAA | phospholipase A2-activating protein |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLTP | phospholipid transfer protein |
| PON1 | paraoxonase 1 |
| PQBP1 | polyglutamine binding protein 1 |
| PRKCE | protein kinase C, epsilon |
| PTHLH | parathyroid hormone-like hormone |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SDC2 | syndecan 2 |
| SDS | serine dehydratase |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SMC1A | structural maintenance of chromosomes 1A |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOCS6 | suppressor of cytokine signaling 6 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRP72 | signal recognition particle 72kDa |
| STXBP5L | syntaxin binding protein 5-like |
| TBX5 | T-box 5 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TMEM63A | transmembrane protein 63A |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TROVE2 | TROVE domain family, member 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEGFA | vascular endothelial growth factor A |
| VEGFB | vascular endothelial growth factor B |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF419 | zinc finger protein 419 |
| ZNF589 | zinc finger protein 589 |
| ZNF609 | zinc finger protein 609 |
| ZNF639 | zinc finger protein 639 |
| ZNF750 | zinc finger protein 750 |
| ZNF862 | zinc finger protein 862 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CABIN1 | calcineurin binding protein 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CENPT | centromere protein T |
| CHPF | chondroitin polymerizing factor |
| CLDN15 | claudin 15 |
| CLGN | calmegin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP2 | dual specificity phosphatase 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FCHSD2 | FCH and double SH3 domains 2 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FZD4 | frizzled class receptor 4 |
| GRAMD4 | GRAM domain containing 4 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2BO | histone cluster 1, H2bo |
| HYI | hydroxypyruvate isomerase (putative) |
| IMPACT | impact RWD domain protein |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPO8 | importin 8 |
| IRF2 | interferon regulatory factor 2 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM7A | lysine (K)-specific demethylase 7A |
| LHX6 | LIM homeobox 6 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPXN | leupaxin |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MCOLN1 | mucolipin 1 |
| MED9 | mediator complex subunit 9 |
| MT1H | metallothionein 1H |
| MYO1E | myosin IE |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OSMR | oncostatin M receptor |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHGDH | phosphoglycerate dehydrogenase |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PTK6 | protein tyrosine kinase 6 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB36 | RAB36, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RNF123 | ring finger protein 123 |
| RNF2 | ring finger protein 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SPATA2L | spermatogenesis associated 2-like |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBX19 | T-box 19 |
| TESC | tescalcin |
| TH | tyrosine hydroxylase |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMPRSS2 | transmembrane protease, serine 2 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| UNC119 | unc-119 homolog (C. elegans) |
| WDR33 | WD repeat domain 33 |
| YY2 | YY2 transcription factor |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF571 | zinc finger protein 571 |
| ZNF574 | zinc finger protein 574 |
| ZNF623 | zinc finger protein 623 |
