| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the pentamidine-4396 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADORA3 | adenosine A3 receptor |
| AIM2 | absent in melanoma 2 |
| AJAP1 | adherens junctions associated protein 1 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ASIC2 | acid sensing (proton gated) ion channel 2 |
| C1QB | complement component 1, q subcomponent, B chain |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C8A | complement component 8, alpha polypeptide |
| CD200 | CD200 molecule |
| CD8A | CD8a molecule |
| CFAP69 | cilia and flagella associated protein 69 |
| CLSTN3 | calsyntenin 3 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYTH4 | cytohesin 4 |
| DMPK | dystrophia myotonica-protein kinase |
| DUSP6 | dual specificity phosphatase 6 |
| ECE1 | endothelin converting enzyme 1 |
| EPN1 | epsin 1 |
| FOXF1 | forkhead box F1 |
| FUT9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GHRH | growth hormone releasing hormone |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GOLGA6A | golgin A6 family, member A |
| GPR4 | G protein-coupled receptor 4 |
| GRAP | GRB2-related adaptor protein |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| ICOS | inducible T-cell co-stimulator |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL11RA | interleukin 11 receptor, alpha |
| IRF8 | interferon regulatory factor 8 |
| ITM2C | integral membrane protein 2C |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KLF13 | Kruppel-like factor 13 |
| KLF6 | Kruppel-like factor 6 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMK1 | LIM domain kinase 1 |
| MAOA | monoamine oxidase A |
| MARS | methionyl-tRNA synthetase |
| MDFI | MyoD family inhibitor |
| MED25 | mediator complex subunit 25 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MORN1 | MORN repeat containing 1 |
| MRC2 | mannose receptor, C type 2 |
| MYLK | myosin light chain kinase |
| OLFM1 | olfactomedin 1 |
| ONECUT2 | one cut homeobox 2 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PAX8 | paired box 8 |
| PCDH1 | protocadherin 1 |
| PCNX | pecanex homolog (Drosophila) |
| PGAP3 | post-GPI attachment to proteins 3 |
| PML | promyelocytic leukemia |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTX3 | pentraxin 3, long |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB36 | RAB36, member RAS oncogene family |
| RARA | retinoic acid receptor, alpha |
| RGS4 | regulator of G-protein signaling 4 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RUNX1 | runt-related transcription factor 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SMAD6 | SMAD family member 6 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| STAC | SH3 and cysteine rich domain |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| TAOK2 | TAO kinase 2 |
| TBKBP1 | TBK1 binding protein 1 |
| TBX10 | T-box 10 |
| TLR2 | toll-like receptor 2 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNS1 | tensin 1 |
| TPP1 | tripeptidyl peptidase I |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZNF277 | zinc finger protein 277 |
| ZNF358 | zinc finger protein 358 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| AFAP1 | actin filament associated protein 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAX | BCL2-associated X protein |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BST2 | bone marrow stromal cell antigen 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CENPQ | centromere protein Q |
| CEP97 | centrosomal protein 97kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CRYGC | crystallin, gamma C |
| CSF1R | colony stimulating factor 1 receptor |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYSF | dysferlin |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV6 | ets variant 6 |
| FAAH | fatty acid amide hydrolase |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR143 | G protein-coupled receptor 143 |
| GRAMD1C | GRAM domain containing 1C |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HHAT | hedgehog acyltransferase |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H4D | histone cluster 1, H4d |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL22 | interleukin 22 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF6 | interferon regulatory factor 6 |
| IRF9 | interferon regulatory factor 9 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LMNB1 | lamin B1 |
| LRRC20 | leucine rich repeat containing 20 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP1S | microtubule-associated protein 1S |
| MAP9 | microtubule-associated protein 9 |
| MED9 | mediator complex subunit 9 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MX2 | MX dynamin-like GTPase 2 |
| NLRX1 | NLR family member X1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHB3 | protocadherin beta 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PRAMEF11 | PRAME family member 11 |
| QSER1 | glutamine and serine rich 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RNF122 | ring finger protein 122 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SIX1 | SIX homeobox 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SP1 | Sp1 transcription factor |
| SSPN | sarcospan |
| STK16 | serine/threonine kinase 16 |
| STRA6 | stimulated by retinoic acid 6 |
| TARP | TCR gamma alternate reading frame protein |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TPSG1 | tryptase gamma 1 |
| TRIM5 | tripartite motif containing 5 |
| TSC22D4 | TSC22 domain family, member 4 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VIM | vimentin |
| ZFHX2 | zinc finger homeobox 2 |
| ZIC3 | Zic family member 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |