| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pentamidine-639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADD2 | adducin 2 (beta) |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATF3 | activating transcription factor 3 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCNG2 | cyclin G2 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAPK1 | death-associated protein kinase 1 |
| DAPK2 | death-associated protein kinase 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DST | dystonin |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 |
| EFCAB1 | EF-hand calcium binding domain 1 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EFNB3 | ephrin-B3 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| ERP44 | endoplasmic reticulum protein 44 |
| FAM162A | family with sequence similarity 162, member A |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GALR3 | galanin receptor 3 |
| GML | glycosylphosphatidylinositol anchored molecule like |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPR35 | G protein-coupled receptor 35 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HLA-E | major histocompatibility complex, class I, E |
| HOXB1 | homeobox B1 |
| HOXC4 | homeobox C4 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KLF15 | Kruppel-like factor 15 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LUZP1 | leucine zipper protein 1 |
| MAGEB2 | melanoma antigen family B2 |
| MEFV | Mediterranean fever |
| MKRN1 | makorin ring finger protein 1 |
| MLN | motilin |
| MRC2 | mannose receptor, C type 2 |
| MTMR2 | myotubularin related protein 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NXPH3 | neurexophilin 3 |
| ONECUT2 | one cut homeobox 2 |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| OR6A2 | olfactory receptor, family 6, subfamily A, member 2 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| POPDC3 | popeye domain containing 3 |
| PRKD3 | protein kinase D3 |
| PVR | poliovirus receptor |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPLP2 | ribosomal protein, large, P2 |
| RPS11 | ribosomal protein S11 |
| RPS2 | ribosomal protein S2 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SYNGR1 | synaptogyrin 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBC1D4 | TBC1 domain family, member 4 |
| TBXA2R | thromboxane A2 receptor |
| TCP11 | t-complex 11, testis-specific |
| TMEM143 | transmembrane protein 143 |
| TMEM161A | transmembrane protein 161A |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPT1 | tumor protein, translationally-controlled 1 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VEGFA | vascular endothelial growth factor A |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WDR48 | WD repeat domain 48 |
| WISP1 | WNT1 inducible signaling pathway protein 1 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF652 | zinc finger protein 652 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ACOT9 | acyl-CoA thioesterase 9 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| AQP8 | aquaporin 8 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| AXIN1 | axin 1 |
| BAGE | B melanoma antigen |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BCL9 | B-cell CLL/lymphoma 9 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CA7 | carbonic anhydrase VII |
| CBX2 | chromobox homolog 2 |
| CCNL2 | cyclin L2 |
| CLDN15 | claudin 15 |
| COG7 | component of oligomeric golgi complex 7 |
| CPTP | ceramide-1-phosphate transfer protein |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DRP2 | dystrophin related protein 2 |
| EDC3 | enhancer of mRNA decapping 3 |
| EMID1 | EMI domain containing 1 |
| EPHA4 | EPH receptor A4 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EXOSC9 | exosome component 9 |
| FANCF | Fanconi anemia, complementation group F |
| FBXO31 | F-box protein 31 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GJA5 | gap junction protein, alpha 5, 40kDa |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GSTT1 | glutathione S-transferase theta 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL28 | kelch-like family member 28 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LOC100272216 | uncharacterized LOC100272216 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| OSMR | oncostatin M receptor |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PAX1 | paired box 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PMP22 | peripheral myelin protein 22 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PRKCD | protein kinase C, delta |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBM14 | RNA binding motif protein 14 |
| RECQL4 | RecQ protein-like 4 |
| RHBDD3 | rhomboid domain containing 3 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF39 | ring finger protein 39 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SETBP1 | SET binding protein 1 |
| SGCE | sarcoglycan, epsilon |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNX6 | sorting nexin 6 |
| SPAG1 | sperm associated antigen 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAC | SH3 and cysteine rich domain |
| SUSD4 | sushi domain containing 4 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| THBS3 | thrombospondin 3 |
| THBS4 | thrombospondin 4 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM127 | transmembrane protein 127 |
| TRABD | TraB domain containing |
| TTC26 | tetratricopeptide repeat domain 26 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR46 | WD repeat domain 46 |
| ZNF35 | zinc finger protein 35 |
| ZNF573 | zinc finger protein 573 |
| ZNF668 | zinc finger protein 668 |
