pentetic acid-3387 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the pentetic acid-3387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ANK1 ankyrin 1, erythrocytic
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ARSD arylsulfatase D
ARTN artemin
AVPR1A arginine vasopressin receptor 1A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C1ORF61 chromosome 1 open reading frame 61
CA5B carbonic anhydrase VB, mitochondrial
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCL21 chemokine (C-C motif) ligand 21
CD6 CD6 molecule
CD70 CD70 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDC42 cell division cycle 42
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH8 cadherin 8, type 2
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP295 centrosomal protein 295kDa
CFAP45 cilia and flagella associated protein 45
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CIB2 calcium and integrin binding family member 2
CTRB2 chymotrypsinogen B2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGKE diacylglycerol kinase, epsilon 64kDa
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ECE1 endothelin converting enzyme 1
ELL2 elongation factor, RNA polymerase II, 2
EXT1 exostosin glycosyltransferase 1
FAM188A family with sequence similarity 188, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXG1 forkhead box G1
FRMD1 FERM domain containing 1
FRY furry homolog (Drosophila)
FSTL1 follistatin-like 1
GPM6A glycoprotein M6A
GSTP1 glutathione S-transferase pi 1
HAB1 B1 for mucin
HDAC6 histone deacetylase 6
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HFE hemochromatosis
HIST1H2BM histone cluster 1, H2bm
IFFO1 intermediate filament family orphan 1
IHH indian hedgehog
ITGB5 integrin, beta 5
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KANK1 KN motif and ankyrin repeat domains 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLK3 kallikrein-related peptidase 3
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KREMEN2 kringle containing transmembrane protein 2
KRT2 keratin 2, type II
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LLGL1 lethal giant larvae homolog 1 (Drosophila)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP11 matrix metallopeptidase 11
MYOF myoferlin
MYOZ3 myozenin 3
NME5 NME/NM23 family member 5
NPHP1 nephronophthisis 1 (juvenile)
NPTX2 neuronal pentraxin II
NTM neurotrimin
PADI3 peptidyl arginine deiminase, type III
PCDHB11 protocadherin beta 11
PCDHGC3 protocadherin gamma subfamily C, 3
PDE4B phosphodiesterase 4B, cAMP-specific
PGLYRP4 peptidoglycan recognition protein 4
PHTF2 putative homeodomain transcription factor 2
PLXNA2 plexin A2
PROSC proline synthetase co-transcribed homolog (bacterial)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVR poliovirus receptor
PYY peptide YY
RAB6A RAB6A, member RAS oncogene family
RECQL5 RecQ protein-like 5
RNF122 ring finger protein 122
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RTEL1 regulator of telomere elongation helicase 1
SAFB scaffold attachment factor B
SCLY selenocysteine lyase
SCNN1B sodium channel, non voltage gated 1 beta subunit
SENP7 SUMO1/sentrin specific peptidase 7
SH2D3A SH2 domain containing 3A
SIRPB1 signal-regulatory protein beta 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPTBN5 spectrin, beta, non-erythrocytic 5
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TEX14 testis expressed 14
TLDC1 TBC/LysM-associated domain containing 1
TYRO3 TYRO3 protein tyrosine kinase
XYLB xylulokinase homolog (H. influenzae)

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADTRP androgen-dependent TFPI-regulating protein
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
AXIN1 axin 1
B9D2 B9 protein domain 2
BMP15 bone morphogenetic protein 15
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC134 coiled-coil domain containing 134
CD82 CD82 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CGREF1 cell growth regulator with EF-hand domain 1
CLCN6 chloride channel, voltage-sensitive 6
CRLF1 cytokine receptor-like factor 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNAL4 dynein, axonemal, light chain 4
EFNA1 ephrin-A1
EGFL7 EGF-like-domain, multiple 7
ELOVL4 ELOVL fatty acid elongase 4
FAM131A family with sequence similarity 131, member A
FAM204A family with sequence similarity 204, member A
FAM212B family with sequence similarity 212, member B
FBXO2 F-box protein 2
FLT4 fms-related tyrosine kinase 4
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GLB1L galactosidase, beta 1-like
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH2L G patch domain containing 2-like
GPR143 G protein-coupled receptor 143
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AL histone cluster 1, H2al
HIST1H4A histone cluster 1, H4a
HOXC8 homeobox C8
HPX hemopexin
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCTD17 potassium channel tetramerization domain containing 17
KLC2 kinesin light chain 2
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LIME1 Lck interacting transmembrane adaptor 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MMRN2 multimerin 2
MST1R macrophage stimulating 1 receptor
NDRG1 N-myc downstream regulated 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
NYNRIN NYN domain and retroviral integrase containing
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PACS1 phosphofurin acidic cluster sorting protein 1
PDIA3 protein disulfide isomerase family A, member 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PRODH proline dehydrogenase (oxidase) 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS20 regulator of G-protein signaling 20
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN2 Ras and Rab interactor 2
RLN1 relaxin 1
RND1 Rho family GTPase 1
RNF208 ring finger protein 208
RUNDC3B RUN domain containing 3B
SCARA3 scavenger receptor class A, member 3
SCGB2A2 secretoglobin, family 2A, member 2
SERGEF secretion regulating guanine nucleotide exchange factor
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SPEG SPEG complex locus
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STBD1 starch binding domain 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBKBP1 TBK1 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TMC5 transmembrane channel-like 5
TMPRSS4 transmembrane protease, serine 4
TSC22D4 TSC22 domain family, member 4
TYRP1 tyrosinase-related protein 1
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VIPR1 vasoactive intestinal peptide receptor 1
WDR33 WD repeat domain 33
XDH xanthine dehydrogenase
ZBTB48 zinc finger and BTB domain containing 48
ZNF134 zinc finger protein 134
ZNF16 zinc finger protein 16
ZNF304 zinc finger protein 304
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747
ZNF750 zinc finger protein 750
ZSWIM1 zinc finger, SWIM-type containing 1